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DTSTART;TZID=America/New_York:20200416T120000
DTEND;TZID=America/New_York:20200416T130000
DTSTAMP:20260423T031501
CREATED:20200226T154726Z
LAST-MODIFIED:20220428T135056Z
UID:2634-1587038400-1587042000@impactcollaboratory.org
SUMMARY:IMPACT Grand Rounds: Health equity as foundational to the design of pragmatic clinical trials
DESCRIPTION:Thursday\, April 16\, 2020\n12:00 – 1:00 pm ET\nAna Quiñones\, PhD\, MS\nAssociate Professor\, Department of Family Medicine\,\nOHSU-PSU School of Public Health\, Oregon Health & Science University \n  \n  \nJonathan Jackson\, PhD\nInstructor in Neurology\, Massachusetts General Hospital\nInstructor\, Harvard Medical School \n  \n  \nZoom Conferencing \nJoin from PC\, Mac\, iOS or Android: https://hebrewseniorlife.zoom.us/j/5479652617     \nDial-In:    +1 646 876 9923 (US Toll) or +1 669 900 6833 (US Toll) \nMeeting ID:  547 965 2617 \nDownload the event flyer \n 
URL:https://impactcollaboratory.org/event/impact-grand-rounds-health-equity-as-foundational-to-the-design-of-pragmatic-clinical-trials/
CATEGORIES:Grand Rounds,upcoming
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200220T120000
DTEND;TZID=America/New_York:20200220T130000
DTSTAMP:20260423T031501
CREATED:20200107T234223Z
LAST-MODIFIED:20200219T212317Z
UID:2441-1582200000-1582203600@impactcollaboratory.org
SUMMARY:Grand Rounds: Modifications and waivers of informed consent in pragmatic clinical trials
DESCRIPTION:Jason Karlawish\, MD\nProfessor of Medicine\, Medical Ethics and Health Policy\, and Neurology\nCo-Director\, Penn Memory Center\, University of Pennsylvania \nThursday\, February 20\, 2020\n12:00 – 1:00 pm EST\n \nJason Karlawish\, MD is a professor of medicine\, medical ethics and health policy\, and neurology at Penn and cares for patients at the Penn Memory Center\, which he co-directs. His research focuses on issues at the intersections of bioethics\, aging and the neurosciences. He leads the Penn Program for Precision Medicine for the Brain (P3MB). P3MB developed standards for Alzheimer’s disease biomarker disclosure and investigates the clinical impacts of this knowledge on persons and their families. He has investigated the psychological and ethical implications of biomarker-based Alzheimer’s disease diagnostics and treatments\, informed consent\, quality of life\, research and treatment decision making\, stigma and voting by persons with cognitive impairment and residents of long term care facilities. \n  \n  \nZoom Conferencing \nJoin from PC\, Mac\, iOS or Android: https://hebrewseniorlife.zoom.us/j/5479652617     \nDial-In:    +1 646 876 9923 (US Toll) or +1 669 900 6833 (US Toll) \nMeeting ID:  547 965 2617
URL:https://impactcollaboratory.org/event/modifications-and-waivers-of-informed-consent-in-pragmatic-clinical-trials/
CATEGORIES:Grand Rounds
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200123T120000
DTEND;TZID=America/New_York:20200123T130000
DTSTAMP:20260423T031501
CREATED:20191219T182348Z
LAST-MODIFIED:20200123T002528Z
UID:2330-1579780800-1579784400@impactcollaboratory.org
SUMMARY:Grand Rounds: Using a Pilot to Test and Refine Your Measurement Strategy
DESCRIPTION:A hallmark of embedded pragmatic trials (ePCTs) is use of existing data sources to evaluate study outcomes. In ePCTs focused on people with dementia\, behavioral outcomes of interest are often under-documented in the existing administrative data. Using a case example\, we describe how a pilot can be used to test the adequacy of existing data for evaluating your ePCT outcome. We also describe a potentially efficient ePCT design that accommodates under-detection in existing data while maintaining large-scale implementation and evaluation. \nSpeaker\nEllen McCreedy\, PhD\, MPH\nAssistant Professor\, Center for Gerontology and Healthcare Research\, Brown University School of Public Health \nEllen McCreedy\, PhD\, MPH is interested in improving the quality of life for people living with advanced dementia. Her research goals are to reduce the amount of futile and burdensome care received at the end of life; and to provide comfort\, meaning\, and moments of joy to people living with dementia and their families. Professor McCreedy received her MPH in Global Health from the University of South Florida\, her PhD in Health Services Research from the University of Minnesota\, and recently completed a postdoctoral research fellowship at Brown University\, Center for Gerontology and Healthcare Research. Dr. McCreedy is directing a pragmatic trial of a personalized music intervention to reduce agitation and isolation in nursing home residents living with dementia. \nLearning Objectives\n\nDescribe how a pilot study can be used to test the adequacy of existing data sources for the purposes of evaluating your ePCT.\nGive three reasons why existing administrative data may suffer from under-detection of behaviors in persons with dementia.\nDiscuss an alternative ePCT design that addresses potential under-detection in existing administrative data sources.\n\nDate & Time\nThursday\, January 23\, 2020\n12:00 – 1:00 pm EST\n \nHow to Join\nZoom Conferencing \nJoin from PC\, Mac\, iOS or Android: https://hebrewseniorlife.zoom.us/j/5479652617     \nDial-In:    +1 646 876 9923 (US Toll) or +1 669 900 6833 (US Toll) \nMeeting ID:  547 965 2617 \nKeywords\nAdministrative data\, dementia-related behaviors\, measurement\, piloting \nAdditional Resources\nMcCreedy EM\, Yang X\, Baier RR\, Rudolph JL\, Thomas KS\, Mor V. Measuring effects of nondrug interventions on behaviors: music & memory pilot study. Journal of the American Geriatrics Society. 2019 Oct;67(10):2134-8.\n\n\n\n 
URL:https://impactcollaboratory.org/event/using-a-pilot-to-test-and-refine-your-measurement-strategy/
CATEGORIES:Grand Rounds
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20191219T120000
DTEND;TZID=America/New_York:20191219T130000
DTSTAMP:20260423T031501
CREATED:20191008T153335Z
LAST-MODIFIED:20191216T150724Z
UID:169-1576756800-1576760400@impactcollaboratory.org
SUMMARY:Grand Rounds
DESCRIPTION:Stepped wedge cluster trials: What\, how\, and when?\nMonica Taljaard\, PhD\nSenior Scientist\, Ottawa Hospital Research Institute\nAssociate Professor\, University of Ottawa\nThursday\, December 19\, 2019\n12:00 – 1:00 pm EST\nLearning Objectives:\n\nDescribe the key characteristics and main types of stepped wedge cluster randomized trials (SW-CRTs) with examples.\nExplain the main approach to analysis and sample size calculation for SW-CRTs.\nDiscuss what is an appropriate justification for using a SW-CRTs.\n\nMonica Taljaard\, PhD is a biostatistician specializing in the design\, analysis\, and ethics of pragmatic cluster randomized and stepped wedge trials. As a member of the Ottawa Hospital Research Institute (OHRI) Methods Center\, she regularly provides biostatistical assistance to investigators in the design\, conduct\, and analysis of pragmatic trials\, pilot trials\, quality improvement interventions\, and health system projects. Since Dr. Taljaard’s academic appointment in 2006\, she has published over 240 peer-reviewed manuscripts and has received over $10M in peer-reviewed research grants as principal investigator from the Canadian Institutes of Health Research\, in addition to $110 million in peer-reviewed research funding as co-investigator. She has collaborated with investigators in the design and analysis of a large-scale pragmatic cluster randomized trials in US Nursing homes\, and studies in palliative and end-of-life care\, dementia\, long-term care\, perioperative care of the frail elderly\, and health care system quality improvement in nursing homes. \nZoom Conferencing\nJoin from PC\, Mac\, iOS or Android: https://hebrewseniorlife.zoom.us/j/5479652617     \nDial-In:    +1 646 876 9923 (US Toll) or +1 669 900 6833 (US Toll) \nMeeting ID:  547 965 2617 \n 
URL:https://impactcollaboratory.org/event/here-is-a-test-event/
LOCATION:NC\, United States
CATEGORIES:Grand Rounds
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20191121T120000
DTEND;TZID=America/New_York:20191121T130000
DTSTAMP:20260423T031501
CREATED:20191107T194358Z
LAST-MODIFIED:20191107T195621Z
UID:539-1574337600-1574341200@impactcollaboratory.org
SUMMARY:Grand Rounds Webinar: Are You Ready for a Pragmatic Trial? The RAPT Model and Implementation Considerations
DESCRIPTION:This webinar will describe the use of the Readiness Assessment for Pragmatic Trials (RAPT) model to asses an intervention’s readiness for a pragmatic randomized\, controlled trial (PCT). PCTs are gaining momentum among among interventionists and funding agencies seeking to accelerate the testing and adoption of evidence-based strategies to improve care and outcomes because their findings are generalizable. Particular attention is being paid to non-pharmacological interventions\, which are often complex and may be difficult to uniformly implement across multiple sites. While many such non-pharmacological interventions have proven efficacious in small trials\, most have not been widely adopted. PCTs could accelerate effectiveness testing and adoption\, yet there are no established criteria to identify interventions ready for testing in a PCT. This webinar will help demonstrate how the RAPT model can help to establish those criteria. \nRead more about the RAPT Model \n \nDownload the event flyer
URL:https://impactcollaboratory.org/event/grand-rounds-webinar-are-you-ready-for-a-pragmatic-trial-the-rapt-model-and-implementation-considerations/
CATEGORIES:Grand Rounds
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