NIA IMPACT Collaboratory

Informational Webinar: Request for Applications for IMPACT Demonstration Project Program Cycle 2
2021-10-19 13:00 - 14:00 (America/New_York)
New Funding Opportunity: Request for Applications for IMPACT Demonstration Project Program

The IMPACT Collaboratory is pleased to announce a Request for Applications (RFA) for the second cycle of the Demonstration Project Program.
IMPACT will fund up to two Demonstration Projects (maximum duration 24 months) designed as full-scale, Stage IV effectiveness embedded pragmatic clinical trials (ePCT) (based on the NIH Stage Model) that test, measure and evaluate the effect of a non-pharmacological care delivery intervention program in a health care system for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners. The goal of the Demonstration Project is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.
Under this mechanism, interventions must be linked to the needs of the health care system. Suitable interventions typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Demonstration Projects will allow health care systems and investigators to gain real-world experience integrating pragmatic non-pharmacological interventions into usual clinical workflow and health care delivery practices in a controlled manner that provides clear information on the impact of the intervention program.
The IMPACT Collaboratory will only fund Demonstration Project applications that include a clinical trial as defined by the National Institutes of Health. Preference will be given to applications that address dementia care for populations historically marginalized or underrepresented in clinical trials and those that promote health equity.
It is anticipated that Demonstration Project awards will be for up to $500,000 in direct costs for a maximum of 24-months and will be non-renewable.
Learn more about the Demonstration Projects Program here.
Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below.
Tuesday, October 19, 2021 at 1:00 pm ET: Registration closed.
Letters of Intent (LOI) by Email – Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis through:
October 29, 2021 @ 5pm ET
Full Applications Due – By invitation only
Applicants selected for further consideration will be invited to submit a full application due:
January 14, 2022 @ 5pm ET
Read the full RFA here. Learn more about our previous Demonstration Project Awardees here.
If you have any questions regarding this funding opportunity, please refer to our Frequently Asked Questions or email IMPACTcollaboratory@hsl.harvard.edu.
Please help to publicize this IMPACT funding opportunity and encourage investigators and colleagues to apply.

UsAgainstAlzheimer's National Alzheimer's Summit
2021-10-13 - 2021-10-14
The UsAgainstAlzheimer’s National Alzheimer’s Summit will be held virtually October 13-14, 2021. Stay tuned for summit details and registration coming soon.

Request for Applications (RFA) Release: Demonstration Project Program
2021-10-04
New Funding Opportunity for the IMPACT Demonstration Project Program

The IMPACT Collaboratory is pleased to announce a Request for Applications (RFA) for the second cycle of the Demonstration Project Program.
IMPACT will fund up to two Demonstration Projects (maximum duration 24 months) designed as full-scale, Stage IV effectiveness embedded pragmatic clinical trials (ePCT) (based on the NIH Stage Model) that test, measure and evaluate the effect of a non-pharmacological care delivery intervention program in a health care system for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners. The goal of the Demonstration Project is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.
Under this mechanism, interventions must be linked to the needs of the health care system. Suitable interventions typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Demonstration Projects will allow health care systems and investigators to gain real-world experience integrating pragmatic non-pharmacological interventions into usual clinical workflow and health care delivery practices in a controlled manner that provides clear information on the impact of the intervention program.
The IMPACT Collaboratory will only fund Demonstration Project applications that include a clinical trial as defined by the National Institutes of Health. Preference will be given to applications that address dementia care for populations historically marginalized or underrepresented in clinical trials and those that promote health equity.
It is anticipated that Demonstration Project awards will be for up to $500,000 in direct costs for a maximum of 24-months and will be non-renewable.
Learn more about the Demonstration Projects Program here.
Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below.
Tuesday, October 19, 2021 at 1:00 pm ET: Registration closed.
Letters of Intent (LOI) by Email – Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis through:
October 29, 2021 @ 5pm ET
Full Applications Due – By invitation only
Applicants selected for further consideration will be invited to submit a full application due:
January 14, 2022 @ 5pm ET
Learn more about our previous Demonstration Project Awardees here.
If you have any questions regarding this funding opportunity, please refer to our Frequently Asked Questions or email IMPACTcollaboratory@hsl.harvard.edu.
Please help to publicize this IMPACT funding opportunity and encourage investigators and colleagues to apply.

Focus on Aging: Federal Partners’ Webinar Series - Mitchell presenting "Evidence- and Goal-Based Decision-Making in Dementia at the End of Life"
2021-09-30 14:30 - 16:00 | https://www.eventbrite.com/e/focus-on-aging-federal-partners-webinar-end-of-life-care-registration-172336632507
IMPACT principal investigator, Susan Mitchell, MD, MPH, presenting on “Evidence- and Goal-Based Decision-Making in Dementia at the End of Life” at the National Institute on Aging’s Focus on Aging: Federal Partners’ Webinar Series.
This webinar series will address important topics for public health and health care professionals, aging services organizations, the research community, and other stakeholders in aging. The series is a joint project of four of the federal agencies that support the health and wellness of older adults in the U.S.: the Administration for Community Living, the Centers for Disease Control and Prevention, the Health Resources and Services Administration, and the National Institute on Aging. In addition to general topics of interest for older adults and those who work with them, each webinar will include information specific to individuals living with Alzheimer’s disease and other types of dementia, as well as their caregivers.
Thursday, September 30th, 2021, 2:30 – 4:00 p.m. ET
Please click here to register for the webinar.
End-of-life care is a term used to describe support and medical care given during the time of life preceding death. Care at the end of life can include support for physical, emotional, spiritual, and practical needs. For those living with dementia, end-of-life care entails unique considerations in these domains, which are critical to maximizing quality of life. The September 2021 Focus on Aging: Federal Partners’ Webinar will delve deeply into the topic of end-of-life care for those living with dementia, with presentations from national experts on the following:

Evidence- and Goal-Based Decision-Making in Dementia at the End of Life
Susan Mitchell, MD, MPH, Harvard Medical School, Hebrew SeniorLife, Marcus Institute for Aging Research
Maximizing Quality of Life in Dementia: A Palliative Approach
Maisha T. Robinson, MD, MS, Mayo Clinic Florida
Palliative Care for Dementia in Action: A Real-World Case
Maribeth Gallagher, DNP, FAAN, Hospice of the Valley
Partnering Staff and Families to Enhance Advance Care Planning for VA Community Living Center Residents with Dementia
Joan Carpenter, PhD, CRNP, ACHPN, University of Maryland School of Nursing, Corporal Michael J. Crescenz VA Medical Center
Walking On: Indigenous Perspectives on End of Life
J. Neil Henderson, PhD, Department of Family Medicine & Biobehavioral Health, University of Minnesota Medical School, Duluth Campus

IMPACT Grand Rounds: Vince Mor, PhD on "Challenges Implementing Innovative Programs in Long Term Care: Examples from Pragmatic Trials"
2021-09-22 12:00 - 13:00 | https://hebrewseniorlife.zoom.us/j/97344810673
Join us for IMPACT Grand Rounds on Wednesday, September 22, 2021 from 12-1pm ET as IMPACT Multiple Principal Investigator, Vince Mor, PhD, presents on “Challenges Implementing Innovative Programs in Long Term Care: Examples from Pragmatic Trials.” Please note that the IMPACT Grand Rounds series is usually on the 3rd Thursday of each month; however, in September, we are moving the date due to the Yom Kippur holiday.
Wednesday, September 22, 2021
12:00 – 1:00 pm ET
ZOOM Details:
Join from PC, Mac, iOS or Android: https://hebrewseniorlife.zoom.us/j/97344810673
Dial-In: +1 312 626 6799 (US Toll) or +1 470 250 9358 (US Toll)
Meeting ID: 973 4481 0673

Deadline: Pilot Grant Cycle 3B Letter of Intent
2021-09-17 08:00 - 17:00
Read Full Pilot Grant Cycle 3B Request for Applications or view online: https://impactcollaboratory.org/pilot-grants-program/
Interested applicants are required to submit a Letter of Intent (LOI) through the Brown University UFunds system at: https://ufunds.brown.edu/. LOIs may be submitted on a rolling basis but no later than September 17, 2021 at 5:00pm ET. LOI decisions will be provided on or before October 22, 2021.
Access to UFunds: UFunds can be accessed either with a Brown University email address or with a Gmail address that has been granted rights to the system. The PI may request Gmail access, or someone else may request permission to submit on behalf of a PI. UFunds is not a multi-user environment. If the PI needs more than one person to work on the application in UFunds, contact Faye_Dvorchak@brown.edu to discuss a possible workaround prior to requesting access to UFunds. The same account must be used to submit materials for the LOI and, if invited, the full proposal application. If you were granted access to UFunds previously, your credentials are still active. New users to UFunds must first request access using a Gmail address here: https://tinyurl.com/UFundsAccess. You will receive an invitation at your Gmail address once access to the UFunds system has been granted. Please note that the registration process can take up to 2 business days, so applicants are strongly encouraged to request access as early as possible.

Informational Webinar: Pilot Grant Cycle 3B RFA
2021-08-23 14:00 - 15:00
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below. The webinar will be recorded and posted online at https://impactcollaboratory.org/pilot-grants-program/.

Monday, August 23, 2021 at 2:00pm ET: Registration closed.

LOIs may be submitted on a rolling basis but no later than September 17, 2021 at 5:00pm ET.
LOI decisions will be provided on or before October 22, 2021.
Applications selected for further consideration will be invited to submit a full proposal that will be due no later than January 14, 2022 at 5:00pm ET.

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Diversity in the PCT Ecosystem – How Do We Develop a Pipeline of Diverse Investigators and Leaders in PCTs?
2021-07-30 13:00 - 14:00
The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore the inclusion of diverse participants in pragmatic clinical trials. This series will include topics on increasing engagement of diverse participants and building trust, including diverse sites, learning from implementation science to maximize diversity, and developing a pipeline of trainees from underrepresented groups to be leaders in pragmatic clinical research.
Guest Moderator:
Lesley Curtis, PhD
Professor in Population Health Sciences
Department of Population Health Sciences
Duke University School of Medicine
Panel:
Marie A. Bernard, MD
Acting NIH Chief Officer for Scientific Workforce Diversity
Deputy Director, National Institute on Aging
National Institutes of Health
George A. Mensah, M.D., FACC
Director, Center for Translation Research and Implementation Science
National Heart, Lung, and Blood Institute (NHLBI)
Office of the Director, National Institutes of Health (NIH)
Natalia Morone, MD, MS
Associate Professor
Boston University School of Medicine
Department of Medicine
General Internal Medicine
Topic: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Diversity in the PCT Ecosystem – How Do We Develop a Pipeline of Diverse Investigators and Leaders in PCTs?
Date: Friday, July 30, 2021, 1:00-2:00 p.m. ET
Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php.
To join the online meeting:
Go to https://dukemed.webex.com/dukemed/j.php?MTID=m228b52a4666c1e24046e11c01ae7bd0d

Alzheimer's Association International Conference 2021 (AAIC) - Mitchell and Mor present
2021-07-30 10:00 - 13:15 | https://alz.org/aaic/registration.asp?utm_source=google&utm_campaign=aaic2021_abstracts&utm_medium=paidsearch&utm_content=google-grants&gclid=Cj0KCQjw_dWGBhDAARIsAMcYuJxwZEhlZBA3sqtz6kubxey5tr8a-HrnuMaK863L1xVeZoYHV8azek4aAo3MEALw_wcB
IMPACT Collaboratory Multiple Principal Investigators Susan Mitchell, MD, MPH and Vince Mor, PhD, will be presenting on Friday, July 30th at the Alzheimer’s Association International Conference 2021 (AAIC).
Friday, July 30th:

8am MT/10am ET: Dr. Mitchell will be presenting, “The NIA Collaboratory: Using Embedded Pragmatic Clinical Trials to Improve Dementia Care,” followed by a live panel discussion at 8:45-9:15am MT/10:45-11:15am ET.
10am MT/12pm ET: Dr. Mor will be presenting, “Are you ready for a Pragmatic Trial? Implementation Considerations,” followed by a live panel discussion at 10:45-11:15am MT/12:45-1:15pm ET.

Register here.

ISCB 2021 (Registration Closed): 42ND ANNUAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR CLINICAL BIOSTATISTICS - "Sample size calculation for stepped wedge cluster randomized trials with multiple levels of clustering"
2021-07-20 09:15 - 09:30
15:15-16:45 (9:15 am ET) Session OC4B: Cluster randomized trials

CHAIR: Andrew Copas

9:15 ET
Kendra Davis-Plourde, Monica Taljaard and Fan Li
Sample size calculation for stepped wedge cluster randomized trials with multiple levels of clustering

ABSTRACT. The stepped wedge cluster randomized trial is an attractive design for evaluating health services delivery or policy interventions. In this design, clusters start in the control condition and gradually cross over to the treatment based on a schedule dictated by random assignment. Outcomes may be assessed on the same individuals over time (i.e., a cohort design) or different individuals (i.e., a cross-sectional design). A key consideration in this design is that sample size calculation and analysis must account for within-period as well as between-period intracluster correlations; cohort designs have additional correlations due to repeated measures on the same individuals. While numerous methods have been developed to account for within- and between-period intracluster correlations with a single level of clustering during each time period, few methods are available to accommodate multiple levels of clustering. Our objectives were to develop computationally-efficient sample size procedures that recognize within-period and between-period intracluster correlations in stepped wedge trials with more than two levels of clustering. Focusing on three levels of clustering and assuming equal cluster-period sizes, we consider three variants, depending on whether each level is treated as a cross-sectional or closed-cohort design. We introduce an extended block exchangeable matrix to characterize the correlation structures both within- and between-clusters in each cluster-period and develop convenient sample size expressions that depend on this correlation structure. With a continuous outcome, we show the sample size expression depends on the correlation structure only through two eigenvalues of the extended block exchangeable matrix. For binary outcomes under a mixed effects framework, we develop a sample size expression based on a first-order Taylor approximation. We conduct simulation studies to examine the finite-sample properties of the proposed sample size algorithms and demonstrate the application of the proposed methods using the Washington State Expedited Partner Therapy trial: a multilevel stepped wedge trial that randomized local health jurisdictions (level 4) consisting of clinics (level 3) and observed patients (level 2) with respect to their Chlamydia infection status (level 1).

More event details: http://www.iscb2021.info/en/pages/iscb-2021-home

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Maximizing Diversity in PCTs – What Can We Learn From Implementation Trials?
2021-07-16 13:00 - 14:00
The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore the inclusion of diverse participants in pragmatic clinical trials. This series will include topics on increasing engagement of diverse participants and building trust, including diverse sites, learning from implementation science to maximize diversity, and developing a pipeline of trainees from underrepresented groups to be leaders in pragmatic clinical research.
Guest Moderator:
David Chambers, DPhil
Deputy Director for Implementation Science
Office of the Director in the Division of Cancer Control and Population Sciences (DCCPS)
National Cancer Institute (NCI)
National Institutes of Health (NIH)
Panel:
Amanda Midboe, PhD
Center for Innovation to Implementation
U.S. Department of Veterans Affairs
Chair of the Implementation Science Work Group for the NIH-DOD-VA Pain Management Collaboratory
Anne Trontell, MD, MPS
Associate Director
Clinical Effectiveness and Decision Science Program
Patient-Centered Outcomes Research Institute (PCORI)
Topic: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Maximizing Diversity in PCTs – What Can We Learn From Implementation Trials?
Date: Friday, July 16, 2021, 1:00-2:00 p.m. ET
Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php.
To join the online meeting:
Go to https://dukemed.webex.com/dukemed/j.php?MTID=m228b52a4666c1e24046e11c01ae7bd0d

Virtual Forum: Artificial Intelligence/Machine Learning (AI/ML) Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD)
2021-06-25 13:00 - 16:00 | https://www.niddk.nih.gov/news/meetings-workshops/2021/artificial-intelligence-machine-learning-consortium
The Artificial Intelligence/Machine Learning (AI/ML) Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD) virtual forum will occur on Friday, June 25th (1:00-4:00 PM EDT). This virtual forum aims to bring together stakeholders across academia, federal agencies, the data science/tech industry, and health care systems and centers who are interested in leveraging artificial intelligence and machine learning (AI/ML) for research, with a primary focus on mitigating health disparities. The purpose of this meeting will be to provide an overview of the initiative approved for funding by NIH and then engage attendees in listening sessions via breakout groups which will focused on three main topics: research interests, computing infrastructure and resources, and training needs. The meeting will conclude with a report back from these smaller breakout discussions and a final summary of the forum discussion and anticipated next steps. The feedback from this event will inform the establishment of mutually beneficial and coordinated partnerships to increase the participation and representation of researchers and communities currently underrepresented in the development of AI/ML models and enhance the capabilities of this emerging technology, beginning with EHR data.

Registration Closed: Due to the enthusiastic response, the AIM-AHEAD Team have reached the participation limit to ensure meaningful conversation, so they have closed registration. Over the next several weeks, they will have additional opportunities for people to provide feedback and ask questions, including a formal Request for Information (RFI) to gather written comments. They will also post a meeting summary of this stakeholder forum. If you have any questions about this event, please contact AIM-AHEAD@od.nih.gov.

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Meeting Participants Where They Are – Outreach, Trust, and Consent to Maximize Diversity
2021-06-25 13:00 - 14:00
Guest Moderator:
Emily O’Brien, PhD
Associate Professor, Department of Population Health Sciences
Duke Clinical Research Institute
Duke University School of Medicine
Panel:
Jonathan Jackson, PhD
Executive Director
Community Access, Recruitment, and Engagement (CARE) Research Center
Massachusetts General Hospital and Harvard Medical School
Judith Schlaeger, PhD, CNM, LAc, FAAN
Associate Professor, Department of Human Development Nursing Science
University of Illinois Chicago
Stacy Sterling, DrPH, MSW, MPH
Research Scientist
Kaiser Permanente Division of Research, Northern California
Topic: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Meeting Participants Where They Are – Outreach, Trust, and Consent to Maximize Diversity
Date: Friday, June 25, 2021, 1:00-2:00 p.m. ET
Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php.
To join the online meeting:
Go to https://dukemed.webex.com/dukemed/j.php?MTID=m228b52a4666c1e24046e11c01ae7bd0d

Pilot Grant Cycle 3A Full Proposals Due @5pm
2021-06-18 17:00
Pilot Grant Cycle 3A Full Proposals Due @5pm. There is a competitive two-step application process for which the required letter of intent (LOI) was due 3/5. Learn more at here: https://impactcollaboratory.org/pilot-grants-program/.

Grand Rounds: Debra Saliba, MD, MPH, and Joan Teno, MD, MS, to present on “Promises and Pitfalls of Existing Data in Nursing Homes”
2021-06-17 12:00 - 13:00
Join us for IMPACT Grand Rounds on Thursday, June 17, 2021 from 12-1pm ET as IMPACT Patient and Caregiver Relevant Outcomes (PCRO) Core Executive Committee Members Debra Saliba, MD, MPH, Anna and Harry Borun Endowed Chair in Geriatrics and Gerontology at UCLA, and Joan M. Teno, MD, MS, Professor of Medicine, Oregon Health & Science University, present on “Promises and Pitfalls of Existing Data in Nursing Homes.”
Thursday, June 17, 2021
12:00 – 1:00 pm ET
ZOOM Details:
Join from PC, Mac, iOS or Android: https://hebrewseniorlife.zoom.us/j/97344810673
Dial-In: +1 312 626 6799 (US Toll) or +1 470 250 9358 (US Toll)
Meeting ID: 973 4481 0673

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Planning for Diversity – Stakeholder Engagement and Site Selection to Maximize Diversity
2021-06-04 13:00 - 14:00
The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore the inclusion of diverse participants in pragmatic clinical trials. This series will include topics on increasing engagement of diverse participants and building trust, including diverse sites, learning from implementation science to maximize diversity, and developing a pipeline of trainees from underrepresented groups to be leaders in pragmatic clinical research.
Guest Moderator:
Wendy Weber, ND, PhD, MPH
Chief, Clinical Research in Complementary and Integrative Health Branch
Division of Extramural Research
National Center for Complementary and Integrative Health (NCCIH)
National Institutes of Health (NIH)
Panel:
BeatPain Utah
Julie Fritz, PhD, PT
Associate Dean for Research, College of Health
Adjunct Professor, Orthopaedic Surgery
Distinguished Professor, Physical Therapy & Athletic Training
Adjunct Professor, Orthopaedic Surgery Operations
University of Utah
David Wetter, PhD, MS
Professor, Population Health Sciences
Adjunct Professor, Psychology
University of Utah
STOP CRC
Gloria Coronado, PhD
Distinguished Investigator
Mitch Greenlick Endowed Scientist for Health Disparities
Kaiser Permanente Center for Health Research
Amanda Petrik, MS
Sr. Research Associate
Center for Health Research
Kaiser Permanente Northwest
Topic: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Planning for Diversity – Stakeholder Engagement and Site Selection to Maximize Diversity
Date: Friday, June 4, 2021, 1:00-2:00 p.m. ET
Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php.
To join the online meeting:
Go to https://dukemed.webex.com/dukemed/j.php?MTID=m228b52a4666c1e24046e11c01ae7bd0d

ISAC/Brown Clinical Trials Seminar - "IMPACT-C: Improving Vaccine Uptake in Skilled Nursing Facilities" - Sarah Berry, MD, MPH
2021-05-27 12:00 - 13:00
Please join us for a lecture from the Joint Seminar Series on Clinical Trials in Aging: Strategies to Improve Nursing Home COVID-19
Vaccine Uptake featuring Sarah Berry, MD, MPH, Harvard Medical School & Hinda and Arthur Marcus Institute for Aging Research.
Nursing homes residents represent about 1% of the US population but, at the height of the pandemic, contributed about 5% of cases and nearly 40% of deaths. Residents and staff were prioritized for vaccination, but staff uptake, in particular, has remained low.
Dr. Berry will present on strategies to improve COVID-19 vaccine uptake, including data from IMPACT Collaboratory observational studies and a pragmatic trial.
The Joint Seminar Series on Clinical Trials in Aging is co-hosted by the Interventional Studies in Aging Center (ISAC) in the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife and the Brown University Center for Long-Term Care Quality & Innovation (Q&I). Lectures focus on issues in the design and execution of clinical trials, including trials currently in the field.
Thursday, May 27, 2021
12:00 – 1:00 pm ET
Zoom Details:
Join from PC, Mac, Linux, iOS or Android: https://hebrewseniorlife.zoom.us/j/89039784165
Or iPhone one-tap (US Toll): +14702509358,,89039784165# or +14703812552,,89039784165#
Dial-In: +1 470 250 9358 (US Toll) or +1 669 900 6833 (US Toll)
Meeting ID: 890 3978 4165

Webinar: Using the NIA Health Disparities Framework to Optimize Equity in Aging Research
2021-05-21 13:00 - 14:30
Duke Center for the Study of Aging and Human Development, REACH Equity, and Roybal Center will present “Using the NIA Health Disparities Framework to Optimize Equity in Aging Research” on May 21 from 1 to 2:30 p.m. EST. Registration closed.

Grand Rounds: Claire Chan, MSc, to present on "Pilot and Feasibility Studies for Pragmatic Cluster Randomised Trials"
2021-05-20 12:00 - 13:00
Join us for IMAPCT Grand Rounds on Thursday, May 20, 2021 from 12-1pm ET as Claire Chan, MSc, statistician with the Queen Mary University of London, presents on Pilot and Feasibility Studies for Pragmatic Cluster Randomised Trials.

Thursday, May 20, 2021
12:00 – 1:00 pm ET
ZOOM Details:
Join from PC, Mac, iOS or Android: https://hebrewseniorlife.zoom.us/j/97344810673
Dial-In: +1 312 626 6799 (US Toll) or +1 470 250 9358 (US Toll)
Meeting ID: 973 4481 0673

NIH Collaboratory Grand Rounds Workshop Series: Inclusion of Diverse Participants in Pragmatic Clinical Trials
2021-05-14 13:00 - 14:00
The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore the inclusion of diverse participants in pragmatic clinical trials. This series will include topics on increasing engagement of diverse participants and building trust, including diverse sites, learning from implementation science to maximize diversity, and developing a pipeline of trainees from underrepresented groups to be leaders in pragmatic clinical research.
The webinar series will kick off on Friday, May 14, at 1 p.m. ET with a keynote presentation by Dr. Clyde Yancy, Vice Dean of Diversity and Inclusion and Chief of Cardiology in the Department of Medicine at Northwestern University Feinberg School of Medicine.

2021 AFTD Education Conference (Two Days)
2021-05-13 12:00 - 16:00
On May 13th and 14th, from 12 p.m. to 4 p.m. ET each day, the Association for Frontotemporal Degeneration (AFTD) will convene its 2021 Education Conference online. People and families affected by FTD will find help, support, and opportunities to connect. Researchers and experts will offer information and guidance through interactive presentations. Health professionals will find information and strategies they can use to better serve families.
Every year, AFTD brings together people and families navigating the FTD journey — as well as researchers and health professionals — to learn about the latest in FTD research, and to learn new strategies for care, management, and support. Our conference offers a chance to connect with others who understand — and share hope for a future free of FTD.
For the health and safety of all, this year’s conference will be broadcast online. It is free to attend.
Learn more on the AFTD website.

2021 Health Care Systems Research Network (HCSRN) Conference
2021-05-11 - 2021-05-12
The HCSRN annual conference is the nation’s preeminent gathering for researchers based in real-world health care systems and our numerous collaborators in academic health systems, funding agencies, and patient-partner communities. The conference offers a diverse slate of content, showcasing rigorous, relevant research on important conditions affecting millions of patients.
IMPACT members are among the panelists presenting, “Aging Research Opportunities for the HCSRN: Finally Reaching Maturity Chronic Conditions, Multi-Morbidity & Aging Populations” at 3:00 PM on Wednesday, May 12.
The National Institute of Aging (NIA) has invested in the development of infrastructure within the framework of aging research. This panel will provide an overview of three major NIA-funded initiatives that lead efforts to support aging research and training of junior investigators. The Health Care Systems Research Network (HCSRN)-Claude D. Pepper Older Americans Independence Centers (HCSRN-OAIC) “AGING” (Advancing Geriatrics Infrastructure & Network Growth) Initiative aims to create a national resource to nurture and advance an interdisciplinary research agenda focused on older adults with multiple chronic conditions. The National Institute on Aging (NIA) IMbedded Pragmatic Alzheimers disease (AD) and AD Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory aims to build the nation’s capacity to conduct pragmatic clinical trials of interventions embedded within health care systems for people living with dementia and their care partners. The US Deprescribing Research Network (USDeN) aims to develop and disseminate evidence about deprescribing for older adults, and in doing so to help improve medication use among older adults and the outcomes that are important to them.

Presenters:

Elizabeth Bayliss, Kaiser Permanente Colorado, CO
Jerry Gurwitz, Meyers Primary Care Institute, MA
Leah Hanson, HealthPartners, MN
Eric Larson, Kaiser Permanente Washington, MA
Marcel Salive, NIA, MD

Advancing Research on Care and Outcome Measurements (ARCOM) funding program Letters of Intent due
2021-05-05
In collaboration with LINC-AD (Leveraging an Interdisciplinary Consortium to Improve Care and Outcomes for Persons Living with Alzheimer’s and Dementia), the Alzheimer’s Association is currently accepting applications for the new Advancing Research on Care and Outcome Measurements (ARCOM) funding program. The goal of the program is to address gaps in care and outcome measurement and advance research efforts to ensure that care providers are implementing evidence-based practices (using measures to guide care provision) and achieving desired outcomes (using measures to assess outcomes). Work funded through ARCOM must directly advance research projects focused on development of new and/or validation of previously developed measures of care and outcomes where measurement gaps exist.
The Alzheimer’s Association anticipates funding up to 8 ACROM proposals for up to $250,000 total funding (direct and indirect costs) over a period of up to two years (minimum of 1 year).
Read the full RFA here. A letter of intent is due by May 5.
To learn more about this funding opportunity, visit their website.

Demonstration Project Proposals Due @ 5pm
2021-04-30 17:00
Demonstration Project Proposals due at 5pm on April 30, 2021. Learn more here: https://impactcollaboratory.org/demonstration-grants-program/.

NIA Virtual Meeting: Development of an NIA Practice-Based Research Network to Conduct AD/ADRD Clinical Research
2021-04-30 14:00 - 17:00
The AGING Initiative is pleased to share an upcoming virtual meeting opportunity on behalf of the National Institute on Aging (NIA):
The NIA will be hosting a virtual meeting on Friday, April 30 from 2:00–5:00pm EST on the “Development of an NIA Practice-Based Research Network to Conduct Alzheimer’s and Related Dementias Clinical Research.”
The meeting will discuss the potential and planning of a practice-based research network (PBRN) to address the disparities gap with the recruitment and retention of diverse and underserved populations to AD/ADRD clinical research studies. PBRNs are networks of health care clinicians and practices working together to answer community-based health care questions and translate research findings into practice—they have the potential to directly engage diverse and underserved communities in AD/ADRD clinical research.
Registration closed.
Keynote Speakers

Lori Minasian, MD
Jonathan N. Tobin, PhD

Panel Speakers

Jennifer Manly, PhD
Andrea Gilmore-Bykovskyi, PhD, RN
Jonathan Jackson, PhD
Vince Mor, PhD

The CDC Nursing Home COVID-19 Immunization Initiative: An Amazing Success Story
2021-04-15 14:00 - 15:00
The AGING Initiative, AGS, and RCCN are co-hosting an upcoming webinar. IMPACT’s Leah Hanson, PhD will be providing introductions. The webinar will be presented by Ruth Link-Gelles, PhD, Staff Epidemiologist for the CDC and Lieutenant Commander for the US Public Health Service Commissioned Corps. Dr. Link-Gelles will be discussing the massive effort and success story of the CDC in immunizing nursing home and long-term care facility residents against COVID-19 following vaccine approval in the United States.
Registration closed.

Grand Rounds: Consuelo H. Wilkins, MD, MSCI to present on "Inclusion, diversity, and equity in pragmatic clinical trials"
2021-04-15 12:00 - 13:00 | https://hebrewseniorlife.zoom.us/j/97344810673
Join us for IMAPCT Grand Rounds on Thursday, April 15, 2021 from 12-1pm ET as Consuelo Wilkins, MD, MSCI presents on “Inclusion, diversity, and equity in pragmatic clinical trials.”
Consuelo H. Wilkins, MD, MSCI
Vice President for Health Equity, VUMC
Associate Dean for Health Equity, Vanderbilt SOM
Professor of Medicine, Division of Geriatric Medicine
Thursday, April 15, 2021
12:00 – 1:00 pm ET
ZOOM Details:
Join from PC, Mac, iOS or Android: https://hebrewseniorlife.zoom.us/j/97344810673
Dial-In: +1 312 626 6799 (US Toll) or +1 470 250 9358 (US Toll)
Meeting ID: 973 4481 0673

Breaking the Silence: Addressing Dementia in Communities of Color
2021-04-15 10:30 - 12:30
Jonathan Jackson, PhD, member of the Executive Committee of the IMPACT Health Equity team will be the keynote speaker for this virtual event.
April marks National Minority Health Month – highlighting health disparities that persist among racial and ethnic minority populations and the ways in which legislation, policies, and programs can help advance health equity. Through this annual event, it is our hope that individuals and families will feel empowered, receive information surrounding the health of communities of color, and share their knowledge with others to take charge of their health. Together, we can keep the momentum going and continue to BREAK THE SILENCE in communities of color; helping individuals and families get access to the services they need.
Registration closed.
This is a virtual event. Please RSVP by April 14, 2021. To register by phone, contact Gail Morgan at (414) 219-5124. After you register, event login instructions will be emailed to you.
Theme: Meet the People Where They Are: Continuing the Dialogue on Inclusivity in Research
Keynote Speaker:
Jonathan D. Jackson, PhD, is the founder and Executive Director of the Community Access, Recruitment, & Engagement (CARE) Research Center at Massachusetts General Hospital and an Instructor in Neurology at Harvard Medical School. His research focuses on midlife and late-life health disparities in clinical settings that affect Black populations. Dr. Jackson serves on Mass General’s Alzheimer’s Disease Research Center (ADRC) and Mass General’s Cancer Center Equity Program, specializing in identifying and overcoming barriers to clinical research for people and communities of color and on statewide and national advisory groups for research recruitment, Alzheimer’s disease and community engagement.

Application Deadline 4/8/21: NIH funded Alzheimer's Association Interdisciplinary Summer Institute (AA-ISRI)
2021-04-08
The Summer Institute is an immersive, no-cost opportunity for early career researchers in psychosocial care and public health to launch a career in dementia science and accelerate breakthroughs in the field. I’m helping to organize it along with Julie Bynum, Matthew Baumgart, Carl Hill, and Sam Fazio as the lead. Several IMPACT members are serving as faculty.
The AA-ISRI will be held in Chicago, August 9-13, 2021, where experts will offer diverse perspectives on ground-breaking research through group sessions and individual mentoring. Applications are due April 8, 2021. Twenty-four applicants will be selected for this exclusive experience.
Please visit the website to learn about the AA-ISRI schedule, faculty and more.
https://www.alz.org/summer-research-institute/overview.asp

Annual IMPACT Training Workshop & Retreat
2021-04-07 - 2021-04-08
The IMPACT Collaboratory will hold its first annual Training Workshop and Retreat, “Building Skills to Conduct Embedded Pragmatic Clinical Trials for People Living with Dementia (PLWD) and their Care Partners,” on April 7-8, 2021.
We are inviting applications from early to mid-career researchers who seek to develop competence in designing and conducting ePCTs of interventions to improve care for PWLD and their care partners. We anticipate accepting up to 25 participants to attend the workshop.
This virtual 1.5-day workshop and retreat will provide a foundation in practical aspects of designing and conducting ePCTs in AD/ADRD through a combination of panel discussions, small group sessions, and networking opportunities with experts in the field. Workshop modules will focus on healthcare systems, implementation science, and study design.
Participants will gain knowledge in ePCT design and method, problem-solve challenges faced in current or planned projects, and network and engage with the larger community of IMPACT investigators. Throughout the program, special attention will be paid to key considerations in design, implementation, and monitoring ePCTs of PLWD and care partners to ensure health equity.
Successful applicants will be expected to complete selected readings and online training prior to the workshop. Please note that all participants will be expected to attend and participate in the entire 1.5-day IMPACT Collaboratory Training Workshop and Retreat.
Please help to publicize this training program and encourage your investigators and colleagues to apply.
EVENT DETAILS (virtual):<
Wednesday, April 7, 2021 from 1:30pm – 4:30pm ET
Thursday, April 8, 2021 from 10:00am – 4:30pm ET
TO APPLY:
For more information and to apply please visit: https://impactcollaboratory.org/training-workshop

Deadline: Friday, January 15, 2021
Application: Closed January 15, 2021.

ELIGIBILITY CRITERIA: Applicants should have an MD, PhD, or equivalent research degree and hold a full-time position at an academic or research organization in the United States. Although the primary audience is early-career investigators, mid-career applicants who are seeking to change their career path to pursue research on ePCTs in AD/ADRD will be considered. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply.
SELECTION CRITERIA: Applicants will be selected based on their demonstrated commitment to improving the care of people living with dementia and/or their caregivers through the conduct of ePCTs in health care systems and the potential impact of the workshop on promoting the applicant’s career in this area.
If you have any questions regarding this opportunity, please email IMPACTcollaboratory@hsl.harvard.edu
