NIA IMPACT Collaboratory

Deadline: Pilot Grant Cycle 3B Full Proposals
2022-01-14 08:00 - 17:00 (America/New_York)
Read Full Pilot Grant Cycle 3B Request for Applications or view online: https://impactcollaboratory.org/pilot-grants-program/
Interested applicants are required to submit a Letter of Intent (LOI) through the Brown University UFunds system at: https://ufunds.brown.edu/. LOIs may be submitted on a rolling basis but no later than September 17, 2021 at 5:00pm ET. LOI decisions will be provided on or before October 22, 2021.
Applications selected for further consideration will be invited to submit a full proposal that will be due no later than January 14, 2022 at 5:00pm ET.
Full proposal applications must be submitted online through Brown University’s UFunds system: https://ufunds.brown.edu.
Access to UFunds: UFunds can be accessed either with a Brown University email address or with a Gmail address that has been granted rights to the system. The PI may request Gmail access, or someone else may request permission to submit on behalf of a PI. UFunds is not a multi-user environment. If the PI needs more than one person to work on the application in UFunds, contact Faye_Dvorchak@brown.edu to discuss a possible workaround prior to requesting access to UFunds. The same account must be used to submit materials for the LOI and, if invited, the full proposal application. If you were granted access to UFunds previously, your credentials are still active. New users to UFunds must first request access using a Gmail address here: https://tinyurl.com/UFundsAccess. You will receive an invitation at your Gmail address once access to the UFunds system has been granted. Please note that the registration process can take up to 2 business days, so applicants are strongly encouraged to request access as early as possible.

Deadline: Demonstration Projects Full Applications Due @ 5pm ET
2022-01-14
NEW FUNDING OPPORTUNITY: The IMPACT Collaboratory released a Request for Applications (RFA) for Demonstration Project Grants on October 4th, with a required Letters of Intent due October 29, 2021. Full applications are due January 14, 2022 at 5pm ET, for those who were invited to submit full applications. To find more details and to read the full RFA, visit: https://impactcollaboratory.org/demonstration-grants-program

Grand Rounds: Partnering with People Living with Dementia and Care Partners in Embedded Pragmatic Clinical Trials
2021-12-16 12:00 - 13:00 | https://hebrewseniorlife.zoom.us/j/97344810673
Join us for Grand Rounds on Thursday, December 16, from 12-1pm ET. Speakers Gary Epstein-Lubow, MD, Associate Professor at Brown University, and Heidi Gil, Chief Strategy Officer at LiveWell, will do an open session on “Partnering with People Living with Dementia and Care Partners in Embedded Pragmatic Clinical Trials (ePCTs),” followed by a panelist discussion with Ula Hwang, MD, MPH, Michael Lepore, PhD, and Joan Monin, PhD.
Zoom Info
Please click the link below to join the webinar:
https://hebrewseniorlife.zoom.us/j/97344810673
Or iPhone one-tap :
US: +13126266799,,97344810673# or +14702509358,,97344810673#
Or Telephone:
Dial(for higher quality, dial a number based on your current location):
US: +1 312 626 6799 or +1 470 250 9358 or +1 470 381 2552 or +1 646 518 9805 or +1 646 876 9923 or +1 651 372 8299 or +1 786 635 1003 or +1 267 831 0333 or +1 301 715 8592 or +1 253 215 8782 or +1 346 248 7799 or +1 602 753 0140 or +1 669 219 2599 or +1 669 900 6833 or +1 720 928 9299 or +1 971 247 1195 or +1 206 337 9723 or +1 213 338 8477
Webinar ID: 973 4481 0673

Academy Health's 14th Annual Conference on the Science of Dissemination & Implementation in Health
2021-12-14 - 2021-12-16
The Annual Conference on the Science of Dissemination and Implementation in Health Conference (D&I) brings together individuals on the frontlines of D&I science, and aims to ensure that evidence is used to inform decisions that will improve the health of individuals and communities.
2021 Theme
Broadening Horizons for Impact: Incorporating Multisectoral Approaches into D&I Science
Registration closed.

Pre-Conference Workshop - Academy Health's 14th Annual Conference on the Science of Dissemination & Implementation in Health
2021-12-13
The NIA IMPACT Collaboratory and NIH Health Care Systems Collaboratory are co-hosting a Pre-Conference Workshop “Convergence of Dissemination & Implementation Research Methods and Embedded Pragmatic Trials” for Academy Health’s Annual Conference on the Science of Dissemination and Implementation in Health Conference (D&I), which brings together individuals on the frontlines of D&I science, and aims to ensure that evidence is used to inform decisions that will improve the health of individuals and communities. 2021 Theme: Broadening Horizons for Impact: Incorporating Multisectoral Approaches into D&I Science.
See full agenda. IMPACT members speakers include Ab Brody, PhD, RN, FAAN, Richard Fortinsky, PhD, Ariel Green, MD, MPH, PhD, Johnathan Jackson, PhD, Ellen McCreedy, MPH, PhD, Vincent Mor, PhD, Anette Totten, PhD. See all speaker bios.
Registration closed.

Application Deadline: 2021 RFA for CICADA Scientists (for July 2022 to June 2023)
2021-12-10 | https://ldi.upenn.edu/education/penn-ldi-training-programs/cicada/center-for-improving-care-delivery-for-the-aging-cicada-request-for-applications/
Overview
Penn’s Center for Improving Care Delivery for the Aging (CICADA) is seeking applications for the 2021–2022 cohort of CICADA Scientists. In collaboration with Penn’s Leonard Davis Institute for Health Economics (LDI), CICADA seeks to enhance the diversity of the aging research workforce by mentoring promising scientists from under-represented backgrounds interested in a career focused on improving health care delivery for older adults, particularly minority older adults.
Up to three CICADA Scientists will be awarded $35,000 to conduct a 1-year research project and will receive mentoring and additional support for career development during the award period. See the CICADA webpage to learn about the full set of resources available to CICADA Scientists.
If you have any questions about the center or this RFA, please contact CICADA@pennmedicine.upenn.edu.
Who Should Apply?
Applications are being accepted from post-doctoral researchers and junior faculty who are underrepresented in research. This includes (1) MD and MD/PhD clinical fellows who have completed their residency, (2) PhD postdoctoral trainees, and (3) MD/PhD, MD, and PhD junior faculty [instructors or assistant professor for less than 3 years at time of application] who are underrepresented, based on the NIH’s Diversity Statement.
Trainees must be committed to developing new research skills in health services research focused on aging. Applicants can be affiliated with any U.S. university and is not limited to those with Penn affiliations.
Application Deadline
December 10, 2021 at 11:59 p.m. ET
Learn more about this opportunity here.

Grand Rounds: Challenges conducting pragmatic trials of interventions for care partner of people living with dementia
2021-11-18 12:00 - 13:00 | https://hebrewseniorlife.zoom.us/j/97344810673
Join us for Grand Rounds on Thursday, November 18, 2021 from 12-1pm ET. IMPACT Principal Investigator Susan Mitchell, MD, MPH will moderate “Challenges conducting pragmatic trials of interventions for care partner of people living with dementia,” with panelists Leah Hanson, PhD, Richard Fortinsky, PhD, and Robert Penfold, PhD.
Panelists
Leah Hanson, PhD
Senior Research Investigator, Senior Director of Research at HealthPartners Neuroscience Center, HealthPartners Institute
Co-Director of Research, HealthPartners Center for Memory & Aging
Richard Fortinsky, PhD
Professor and Health Net, Inc. Endowed Chair in Geriatrics and Gerontology
UConn Center on Aging | UConn Health
Robert Penfold, PhD
Senior Investigator,
Kaiser Permanente Washington Health Research Institute
Zoom Info
Please click the link below to join the webinar:
https://hebrewseniorlife.zoom.us/j/97344810673
Or iPhone one-tap :
US: +13126266799,,97344810673# or +14702509358,,97344810673#
Or Telephone:
Dial(for higher quality, dial a number based on your current location):
US: +1 312 626 6799 or +1 470 250 9358 or +1 470 381 2552 or +1 646 518 9805 or +1 646 876 9923 or +1 651 372 8299 or +1 786 635 1003 or +1 267 831 0333 or +1 301 715 8592 or +1 253 215 8782 or +1 346 248 7799 or +1 602 753 0140 or +1 669 219 2599 or +1 669 900 6833 or +1 720 928 9299 or +1 971 247 1195 or +1 206 337 9723 or +1 213 338 8477
Webinar ID: 973 4481 0673

GSA Webinar: Applying the Science of Behavior Change to Intervention Development for Diverse Older Adults
2021-11-15 13:00 - 17:30
This webinar is open to members of the Gerontological Society of America. Click here for more information.
Monday, November 15, 2021
1 to 2:30 p.m. ET, Session I – Exemplary Studies
4 to 5:30 p.m. ET, Session II – Supporting Further Research
See registration instructions above
Free for members; $75 for nonmembers
The webinar speakers will present on how social and psychological factors shape health-related behavior change and will enhance attendees’ understanding of the issues by highlighting variations in mechanisms that create and sustain health behavior changes. In this webinar, attendees will:

Be exposed to various theoretical frameworks for behavior change, and how these have been developed and applied to diverse populations.
Hear examples of how various approaches can be used to improve behavioral interventions and healthy lifestyles for diverse aging populations.
Identify areas of needed research to better apply these principles to interventions for diverse older adults, especially for the development of interventions for Alzheimer’s caregivers.

Presented by:

Lisa Onken, PhD, Director, Behavior Change and Intervention Program, Division of Behavioral and Social Research, National Institute on Aging of the National Institutes of Health
Jun Ma, MD, PhD, FAHA, FABMR, FSBM, Beth and George Vitoux Distinguished Professor of Medicine, University of Illinois at Chicago.
Michelle Carlson, PhD, FGSA, Professor, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health; core faculty, Center on Aging and Health, Johns Hopkins Medical Institutions..
Donald Edmondson, PhD, MPH, Associate Professor, Medicine and Psychiatry, Columbia University Irving Medical Center; Director, Center for Behavioral Cardiovascular Health, CUIMC.
Fadel Zeidan, PhD, Executive Director, University of California, San Diego, Center for Mindfulness; Assistant Professor, Anesthesiology, UCSD.
Vincent Mor, PhD, Professor, Medical Science, Department of Health Services, Policy, and Practice; Florence Pirce Grant University Professor, Brown University School of Public Health.

Deadline: US Deprescribing Pilot & Grant Planning Awards Letter of Intent (Required) Due
2021-11-12
The US Deprescribing Research Network is pleased to announce two new Request for Applications for Pilot Awards and Grant Planning Awards. The total budget per award is up to $60,000 over 1 year (combined directs and indirects), and one of several awards will be made in collaboration with the AGING Initiative (HCSRN-OAIC).
Informational Webinar: October 14, 2021 | 2PM – 3PM ET / 11AM – 12PM PT
Letter of Intent (Required) Due: November 12, 2021
Full Application Due: January 28, 2022
Learn more about these funding opportunities here: https://deprescribingresearch.org/network-activities/grant-opportunities/

GSA 2021 Annual Scientific Meeting
2021-11-11 - 2021-11-13
The Gerontological Society of America Annual Scientific Meeting will be held online from November 10-13, 2021. Several members of the IMPACT Collaboratory will be presenting during the event. Learn more and register at https://www.gsa2021.org/ .

Deadline: Demonstration Project Letter of Intent Due @ 5pm ET
2021-10-29
NEW FUNDING OPPORTUNITY: We are pleased to announce that the IMPACT Collaboratory has released a Request for Applications (RFA) for Demonstration Project Grants. Letters of Intent are required and due no later than October 29, 2021. For more details and to read the full RFA, visit: https://impactcollaboratory.org/demonstration-grants-program

Training Workshop Application Deadline
2021-10-22 08:00 - 17:00
The IMPACT Collaboratory will hold the second annual Training Workshop on January 26-27, 2022 entitled Building Skills to Conduct Embedded Pragmatic Clinical Trials (ePCTs) among People Living with Dementia (PLWD) and their Care Partners. This virtual 1.5-day workshop will provide a foundation in practical aspects of designing and conducting ePCTs in Alzheimer’s disease and related dementias (AD/ADRD) through a combination of activities including: panel discussions, small group sessions, and networking opportunities with experts in the field.
The training workshop will feature 3 modules focused on:
1) integrating health equity into ePCTs,
2) ethical considerations for ePCTs for people living with dementia and care partners, and
3) the challenges and opportunities related to conducting ePCTs with care partners of people living with dementia.
We are inviting applications from early to mid-stage researchers who seek to develop competence in designing and conducting ePCTs of non-pharmacological interventions embedded in health care systems (HCS) for people living with dementia and care partners.
Successful applicants will be expected to complete selected readings and online training prior to the workshop.
Upon completion of the workshop, participants will be able to:https://app.smartsheet.com/b/form/b3939d1e720c44369fd9009a10894add

Transmit knowledge about designing and conducting ePCTs among PLWD and care partners in health care systems that integrates considerations of health equity
Address common ethical considerations in designing and conducting ePCTs for PLWD and care partners
Apply the acquired knowledge to move their current and future research in ePCTs forward, including applying for competitive funding

All participants are expected to attend and participate in the entire 1.5-day event.
Apply here.

Grand Rounds: Karen Lyons, PhD, FGSA, on “Dyadic designs, their foundation on theory and analytic methods”
2021-10-21 12:00 - 13:00 | https://hebrewseniorlife.zoom.us/j/97344810673
Join us for IMPACT Grand Rounds on Thursday, October 21, 2021 from 12-1pm ET as Karen S. Lyons, PhD, FGSA, presents on “Dyadic designs, their foundation on theory and analytic methods.”
Speaker: Karen S. Lyons, PhD, FGSA (she/hers), Professor, Boston College William F. Connell School of Nursing
Thursday, October 21, 2021
12:00 – 1:00 pm ET
ZOOM Details:
Join from PC, Mac, iOS or Android: https://hebrewseniorlife.zoom.us/j/97344810673
Dial-In: +1 312 626 6799 (US Toll) or +1 470 250 9358 (US Toll)
Meeting ID: 973 4481 0673

Informational Webinar: Request for Applications for IMPACT Demonstration Project Program Cycle 2
2021-10-19 13:00 - 14:00
New Funding Opportunity: Request for Applications for IMPACT Demonstration Project Program

The IMPACT Collaboratory is pleased to announce a Request for Applications (RFA) for the second cycle of the Demonstration Project Program.
IMPACT will fund up to two Demonstration Projects (maximum duration 24 months) designed as full-scale, Stage IV effectiveness embedded pragmatic clinical trials (ePCT) (based on the NIH Stage Model) that test, measure and evaluate the effect of a non-pharmacological care delivery intervention program in a health care system for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners. The goal of the Demonstration Project is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.
Under this mechanism, interventions must be linked to the needs of the health care system. Suitable interventions typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Demonstration Projects will allow health care systems and investigators to gain real-world experience integrating pragmatic non-pharmacological interventions into usual clinical workflow and health care delivery practices in a controlled manner that provides clear information on the impact of the intervention program.
The IMPACT Collaboratory will only fund Demonstration Project applications that include a clinical trial as defined by the National Institutes of Health. Preference will be given to applications that address dementia care for populations historically marginalized or underrepresented in clinical trials and those that promote health equity.
It is anticipated that Demonstration Project awards will be for up to $500,000 in direct costs for a maximum of 24-months and will be non-renewable.
Learn more about the Demonstration Projects Program here.
Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below.
Tuesday, October 19, 2021 at 1:00 pm ET: Registration closed.
Letters of Intent (LOI) by Email – Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis through:
October 29, 2021 @ 5pm ET
Full Applications Due – By invitation only
Applicants selected for further consideration will be invited to submit a full application due:
January 14, 2022 @ 5pm ET
Read the full RFA here. Learn more about our previous Demonstration Project Awardees here.
If you have any questions regarding this funding opportunity, please refer to our Frequently Asked Questions or email IMPACTcollaboratory@hsl.harvard.edu.
Please help to publicize this IMPACT funding opportunity and encourage investigators and colleagues to apply.

UsAgainstAlzheimer's National Alzheimer's Summit
2021-10-13 - 2021-10-14
The UsAgainstAlzheimer’s National Alzheimer’s Summit will be held virtually October 13-14, 2021. Stay tuned for summit details and registration coming soon.

Request for Applications (RFA) Release: Demonstration Project Program
2021-10-04
New Funding Opportunity for the IMPACT Demonstration Project Program

The IMPACT Collaboratory is pleased to announce a Request for Applications (RFA) for the second cycle of the Demonstration Project Program.
IMPACT will fund up to two Demonstration Projects (maximum duration 24 months) designed as full-scale, Stage IV effectiveness embedded pragmatic clinical trials (ePCT) (based on the NIH Stage Model) that test, measure and evaluate the effect of a non-pharmacological care delivery intervention program in a health care system for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners. The goal of the Demonstration Project is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.
Under this mechanism, interventions must be linked to the needs of the health care system. Suitable interventions typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Demonstration Projects will allow health care systems and investigators to gain real-world experience integrating pragmatic non-pharmacological interventions into usual clinical workflow and health care delivery practices in a controlled manner that provides clear information on the impact of the intervention program.
The IMPACT Collaboratory will only fund Demonstration Project applications that include a clinical trial as defined by the National Institutes of Health. Preference will be given to applications that address dementia care for populations historically marginalized or underrepresented in clinical trials and those that promote health equity.
It is anticipated that Demonstration Project awards will be for up to $500,000 in direct costs for a maximum of 24-months and will be non-renewable.
Learn more about the Demonstration Projects Program here.
Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below.
Tuesday, October 19, 2021 at 1:00 pm ET: Registration closed.
Letters of Intent (LOI) by Email – Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis through:
October 29, 2021 @ 5pm ET
Full Applications Due – By invitation only
Applicants selected for further consideration will be invited to submit a full application due:
January 14, 2022 @ 5pm ET
Learn more about our previous Demonstration Project Awardees here.
If you have any questions regarding this funding opportunity, please refer to our Frequently Asked Questions or email IMPACTcollaboratory@hsl.harvard.edu.
Please help to publicize this IMPACT funding opportunity and encourage investigators and colleagues to apply.

Focus on Aging: Federal Partners’ Webinar Series - Mitchell presenting "Evidence- and Goal-Based Decision-Making in Dementia at the End of Life"
2021-09-30 14:30 - 16:00 | https://www.eventbrite.com/e/focus-on-aging-federal-partners-webinar-end-of-life-care-registration-172336632507
IMPACT principal investigator, Susan Mitchell, MD, MPH, presenting on “Evidence- and Goal-Based Decision-Making in Dementia at the End of Life” at the National Institute on Aging’s Focus on Aging: Federal Partners’ Webinar Series.
This webinar series will address important topics for public health and health care professionals, aging services organizations, the research community, and other stakeholders in aging. The series is a joint project of four of the federal agencies that support the health and wellness of older adults in the U.S.: the Administration for Community Living, the Centers for Disease Control and Prevention, the Health Resources and Services Administration, and the National Institute on Aging. In addition to general topics of interest for older adults and those who work with them, each webinar will include information specific to individuals living with Alzheimer’s disease and other types of dementia, as well as their caregivers.
Thursday, September 30th, 2021, 2:30 – 4:00 p.m. ET
Please click here to register for the webinar.
End-of-life care is a term used to describe support and medical care given during the time of life preceding death. Care at the end of life can include support for physical, emotional, spiritual, and practical needs. For those living with dementia, end-of-life care entails unique considerations in these domains, which are critical to maximizing quality of life. The September 2021 Focus on Aging: Federal Partners’ Webinar will delve deeply into the topic of end-of-life care for those living with dementia, with presentations from national experts on the following:

Evidence- and Goal-Based Decision-Making in Dementia at the End of Life
Susan Mitchell, MD, MPH, Harvard Medical School, Hebrew SeniorLife, Marcus Institute for Aging Research
Maximizing Quality of Life in Dementia: A Palliative Approach
Maisha T. Robinson, MD, MS, Mayo Clinic Florida
Palliative Care for Dementia in Action: A Real-World Case
Maribeth Gallagher, DNP, FAAN, Hospice of the Valley
Partnering Staff and Families to Enhance Advance Care Planning for VA Community Living Center Residents with Dementia
Joan Carpenter, PhD, CRNP, ACHPN, University of Maryland School of Nursing, Corporal Michael J. Crescenz VA Medical Center
Walking On: Indigenous Perspectives on End of Life
J. Neil Henderson, PhD, Department of Family Medicine & Biobehavioral Health, University of Minnesota Medical School, Duluth Campus

IMPACT Grand Rounds: Vince Mor, PhD on "Challenges Implementing Innovative Programs in Long Term Care: Examples from Pragmatic Trials"
2021-09-22 12:00 - 13:00 | https://hebrewseniorlife.zoom.us/j/97344810673
Join us for IMPACT Grand Rounds on Wednesday, September 22, 2021 from 12-1pm ET as IMPACT Multiple Principal Investigator, Vince Mor, PhD, presents on “Challenges Implementing Innovative Programs in Long Term Care: Examples from Pragmatic Trials.” Please note that the IMPACT Grand Rounds series is usually on the 3rd Thursday of each month; however, in September, we are moving the date due to the Yom Kippur holiday.
Wednesday, September 22, 2021
12:00 – 1:00 pm ET
ZOOM Details:
Join from PC, Mac, iOS or Android: https://hebrewseniorlife.zoom.us/j/97344810673
Dial-In: +1 312 626 6799 (US Toll) or +1 470 250 9358 (US Toll)
Meeting ID: 973 4481 0673

Deadline: Pilot Grant Cycle 3B Letter of Intent
2021-09-17 08:00 - 17:00
Read Full Pilot Grant Cycle 3B Request for Applications or view online: https://impactcollaboratory.org/pilot-grants-program/
Interested applicants are required to submit a Letter of Intent (LOI) through the Brown University UFunds system at: https://ufunds.brown.edu/. LOIs may be submitted on a rolling basis but no later than September 17, 2021 at 5:00pm ET. LOI decisions will be provided on or before October 22, 2021.
Access to UFunds: UFunds can be accessed either with a Brown University email address or with a Gmail address that has been granted rights to the system. The PI may request Gmail access, or someone else may request permission to submit on behalf of a PI. UFunds is not a multi-user environment. If the PI needs more than one person to work on the application in UFunds, contact Faye_Dvorchak@brown.edu to discuss a possible workaround prior to requesting access to UFunds. The same account must be used to submit materials for the LOI and, if invited, the full proposal application. If you were granted access to UFunds previously, your credentials are still active. New users to UFunds must first request access using a Gmail address here: https://tinyurl.com/UFundsAccess. You will receive an invitation at your Gmail address once access to the UFunds system has been granted. Please note that the registration process can take up to 2 business days, so applicants are strongly encouraged to request access as early as possible.

Informational Webinar: Pilot Grant Cycle 3B RFA
2021-08-23 14:00 - 15:00
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below. The webinar will be recorded and posted online at https://impactcollaboratory.org/pilot-grants-program/.

Monday, August 23, 2021 at 2:00pm ET: Registration closed.

LOIs may be submitted on a rolling basis but no later than September 17, 2021 at 5:00pm ET.
LOI decisions will be provided on or before October 22, 2021.
Applications selected for further consideration will be invited to submit a full proposal that will be due no later than January 14, 2022 at 5:00pm ET.

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Diversity in the PCT Ecosystem – How Do We Develop a Pipeline of Diverse Investigators and Leaders in PCTs?
2021-07-30 13:00 - 14:00
The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore the inclusion of diverse participants in pragmatic clinical trials. This series will include topics on increasing engagement of diverse participants and building trust, including diverse sites, learning from implementation science to maximize diversity, and developing a pipeline of trainees from underrepresented groups to be leaders in pragmatic clinical research.
Guest Moderator:
Lesley Curtis, PhD
Professor in Population Health Sciences
Department of Population Health Sciences
Duke University School of Medicine
Panel:
Marie A. Bernard, MD
Acting NIH Chief Officer for Scientific Workforce Diversity
Deputy Director, National Institute on Aging
National Institutes of Health
George A. Mensah, M.D., FACC
Director, Center for Translation Research and Implementation Science
National Heart, Lung, and Blood Institute (NHLBI)
Office of the Director, National Institutes of Health (NIH)
Natalia Morone, MD, MS
Associate Professor
Boston University School of Medicine
Department of Medicine
General Internal Medicine
Topic: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Diversity in the PCT Ecosystem – How Do We Develop a Pipeline of Diverse Investigators and Leaders in PCTs?
Date: Friday, July 30, 2021, 1:00-2:00 p.m. ET
Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php.
To join the online meeting:
Go to https://dukemed.webex.com/dukemed/j.php?MTID=m228b52a4666c1e24046e11c01ae7bd0d

Alzheimer's Association International Conference 2021 (AAIC) - Mitchell and Mor present
2021-07-30 10:00 - 13:15 | https://alz.org/aaic/registration.asp?utm_source=google&utm_campaign=aaic2021_abstracts&utm_medium=paidsearch&utm_content=google-grants&gclid=Cj0KCQjw_dWGBhDAARIsAMcYuJxwZEhlZBA3sqtz6kubxey5tr8a-HrnuMaK863L1xVeZoYHV8azek4aAo3MEALw_wcB
IMPACT Collaboratory Multiple Principal Investigators Susan Mitchell, MD, MPH and Vince Mor, PhD, will be presenting on Friday, July 30th at the Alzheimer’s Association International Conference 2021 (AAIC).
Friday, July 30th:

8am MT/10am ET: Dr. Mitchell will be presenting, “The NIA Collaboratory: Using Embedded Pragmatic Clinical Trials to Improve Dementia Care,” followed by a live panel discussion at 8:45-9:15am MT/10:45-11:15am ET.
10am MT/12pm ET: Dr. Mor will be presenting, “Are you ready for a Pragmatic Trial? Implementation Considerations,” followed by a live panel discussion at 10:45-11:15am MT/12:45-1:15pm ET.

Register here.

ISCB 2021 (Registration Closed): 42ND ANNUAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR CLINICAL BIOSTATISTICS - "Sample size calculation for stepped wedge cluster randomized trials with multiple levels of clustering"
2021-07-20 09:15 - 09:30
15:15-16:45 (9:15 am ET) Session OC4B: Cluster randomized trials

CHAIR: Andrew Copas

9:15 ET
Kendra Davis-Plourde, Monica Taljaard and Fan Li
Sample size calculation for stepped wedge cluster randomized trials with multiple levels of clustering

ABSTRACT. The stepped wedge cluster randomized trial is an attractive design for evaluating health services delivery or policy interventions. In this design, clusters start in the control condition and gradually cross over to the treatment based on a schedule dictated by random assignment. Outcomes may be assessed on the same individuals over time (i.e., a cohort design) or different individuals (i.e., a cross-sectional design). A key consideration in this design is that sample size calculation and analysis must account for within-period as well as between-period intracluster correlations; cohort designs have additional correlations due to repeated measures on the same individuals. While numerous methods have been developed to account for within- and between-period intracluster correlations with a single level of clustering during each time period, few methods are available to accommodate multiple levels of clustering. Our objectives were to develop computationally-efficient sample size procedures that recognize within-period and between-period intracluster correlations in stepped wedge trials with more than two levels of clustering. Focusing on three levels of clustering and assuming equal cluster-period sizes, we consider three variants, depending on whether each level is treated as a cross-sectional or closed-cohort design. We introduce an extended block exchangeable matrix to characterize the correlation structures both within- and between-clusters in each cluster-period and develop convenient sample size expressions that depend on this correlation structure. With a continuous outcome, we show the sample size expression depends on the correlation structure only through two eigenvalues of the extended block exchangeable matrix. For binary outcomes under a mixed effects framework, we develop a sample size expression based on a first-order Taylor approximation. We conduct simulation studies to examine the finite-sample properties of the proposed sample size algorithms and demonstrate the application of the proposed methods using the Washington State Expedited Partner Therapy trial: a multilevel stepped wedge trial that randomized local health jurisdictions (level 4) consisting of clinics (level 3) and observed patients (level 2) with respect to their Chlamydia infection status (level 1).

More event details: http://www.iscb2021.info/en/pages/iscb-2021-home

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Maximizing Diversity in PCTs – What Can We Learn From Implementation Trials?
2021-07-16 13:00 - 14:00
The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore the inclusion of diverse participants in pragmatic clinical trials. This series will include topics on increasing engagement of diverse participants and building trust, including diverse sites, learning from implementation science to maximize diversity, and developing a pipeline of trainees from underrepresented groups to be leaders in pragmatic clinical research.
Guest Moderator:
David Chambers, DPhil
Deputy Director for Implementation Science
Office of the Director in the Division of Cancer Control and Population Sciences (DCCPS)
National Cancer Institute (NCI)
National Institutes of Health (NIH)
Panel:
Amanda Midboe, PhD
Center for Innovation to Implementation
U.S. Department of Veterans Affairs
Chair of the Implementation Science Work Group for the NIH-DOD-VA Pain Management Collaboratory
Anne Trontell, MD, MPS
Associate Director
Clinical Effectiveness and Decision Science Program
Patient-Centered Outcomes Research Institute (PCORI)
Topic: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Maximizing Diversity in PCTs – What Can We Learn From Implementation Trials?
Date: Friday, July 16, 2021, 1:00-2:00 p.m. ET
Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php.
To join the online meeting:
Go to https://dukemed.webex.com/dukemed/j.php?MTID=m228b52a4666c1e24046e11c01ae7bd0d

Virtual Forum: Artificial Intelligence/Machine Learning (AI/ML) Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD)
2021-06-25 13:00 - 16:00 | https://www.niddk.nih.gov/news/meetings-workshops/2021/artificial-intelligence-machine-learning-consortium
The Artificial Intelligence/Machine Learning (AI/ML) Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD) virtual forum will occur on Friday, June 25th (1:00-4:00 PM EDT). This virtual forum aims to bring together stakeholders across academia, federal agencies, the data science/tech industry, and health care systems and centers who are interested in leveraging artificial intelligence and machine learning (AI/ML) for research, with a primary focus on mitigating health disparities. The purpose of this meeting will be to provide an overview of the initiative approved for funding by NIH and then engage attendees in listening sessions via breakout groups which will focused on three main topics: research interests, computing infrastructure and resources, and training needs. The meeting will conclude with a report back from these smaller breakout discussions and a final summary of the forum discussion and anticipated next steps. The feedback from this event will inform the establishment of mutually beneficial and coordinated partnerships to increase the participation and representation of researchers and communities currently underrepresented in the development of AI/ML models and enhance the capabilities of this emerging technology, beginning with EHR data.

Registration Closed: Due to the enthusiastic response, the AIM-AHEAD Team have reached the participation limit to ensure meaningful conversation, so they have closed registration. Over the next several weeks, they will have additional opportunities for people to provide feedback and ask questions, including a formal Request for Information (RFI) to gather written comments. They will also post a meeting summary of this stakeholder forum. If you have any questions about this event, please contact AIM-AHEAD@od.nih.gov.

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Meeting Participants Where They Are – Outreach, Trust, and Consent to Maximize Diversity
2021-06-25 13:00 - 14:00
Guest Moderator:
Emily O’Brien, PhD
Associate Professor, Department of Population Health Sciences
Duke Clinical Research Institute
Duke University School of Medicine
Panel:
Jonathan Jackson, PhD
Executive Director
Community Access, Recruitment, and Engagement (CARE) Research Center
Massachusetts General Hospital and Harvard Medical School
Judith Schlaeger, PhD, CNM, LAc, FAAN
Associate Professor, Department of Human Development Nursing Science
University of Illinois Chicago
Stacy Sterling, DrPH, MSW, MPH
Research Scientist
Kaiser Permanente Division of Research, Northern California
Topic: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Meeting Participants Where They Are – Outreach, Trust, and Consent to Maximize Diversity
Date: Friday, June 25, 2021, 1:00-2:00 p.m. ET
Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php.
To join the online meeting:
Go to https://dukemed.webex.com/dukemed/j.php?MTID=m228b52a4666c1e24046e11c01ae7bd0d

Pilot Grant Cycle 3A Full Proposals Due @5pm
2021-06-18 17:00
Pilot Grant Cycle 3A Full Proposals Due @5pm. There is a competitive two-step application process for which the required letter of intent (LOI) was due 3/5. Learn more at here: https://impactcollaboratory.org/pilot-grants-program/.

Grand Rounds: Debra Saliba, MD, MPH, and Joan Teno, MD, MS, to present on “Promises and Pitfalls of Existing Data in Nursing Homes”
2021-06-17 12:00 - 13:00
Join us for IMPACT Grand Rounds on Thursday, June 17, 2021 from 12-1pm ET as IMPACT Patient and Caregiver Relevant Outcomes (PCRO) Core Executive Committee Members Debra Saliba, MD, MPH, Anna and Harry Borun Endowed Chair in Geriatrics and Gerontology at UCLA, and Joan M. Teno, MD, MS, Professor of Medicine, Oregon Health & Science University, present on “Promises and Pitfalls of Existing Data in Nursing Homes.”
Thursday, June 17, 2021
12:00 – 1:00 pm ET
ZOOM Details:
Join from PC, Mac, iOS or Android: https://hebrewseniorlife.zoom.us/j/97344810673
Dial-In: +1 312 626 6799 (US Toll) or +1 470 250 9358 (US Toll)
Meeting ID: 973 4481 0673

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Planning for Diversity – Stakeholder Engagement and Site Selection to Maximize Diversity
2021-06-04 13:00 - 14:00
The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore the inclusion of diverse participants in pragmatic clinical trials. This series will include topics on increasing engagement of diverse participants and building trust, including diverse sites, learning from implementation science to maximize diversity, and developing a pipeline of trainees from underrepresented groups to be leaders in pragmatic clinical research.
Guest Moderator:
Wendy Weber, ND, PhD, MPH
Chief, Clinical Research in Complementary and Integrative Health Branch
Division of Extramural Research
National Center for Complementary and Integrative Health (NCCIH)
National Institutes of Health (NIH)
Panel:
BeatPain Utah
Julie Fritz, PhD, PT
Associate Dean for Research, College of Health
Adjunct Professor, Orthopaedic Surgery
Distinguished Professor, Physical Therapy & Athletic Training
Adjunct Professor, Orthopaedic Surgery Operations
University of Utah
David Wetter, PhD, MS
Professor, Population Health Sciences
Adjunct Professor, Psychology
University of Utah
STOP CRC
Gloria Coronado, PhD
Distinguished Investigator
Mitch Greenlick Endowed Scientist for Health Disparities
Kaiser Permanente Center for Health Research
Amanda Petrik, MS
Sr. Research Associate
Center for Health Research
Kaiser Permanente Northwest
Topic: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Planning for Diversity – Stakeholder Engagement and Site Selection to Maximize Diversity
Date: Friday, June 4, 2021, 1:00-2:00 p.m. ET
Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php.
To join the online meeting:
Go to https://dukemed.webex.com/dukemed/j.php?MTID=m228b52a4666c1e24046e11c01ae7bd0d

ISAC/Brown Clinical Trials Seminar - "IMPACT-C: Improving Vaccine Uptake in Skilled Nursing Facilities" - Sarah Berry, MD, MPH
2021-05-27 12:00 - 13:00
Please join us for a lecture from the Joint Seminar Series on Clinical Trials in Aging: Strategies to Improve Nursing Home COVID-19
Vaccine Uptake featuring Sarah Berry, MD, MPH, Harvard Medical School & Hinda and Arthur Marcus Institute for Aging Research.
Nursing homes residents represent about 1% of the US population but, at the height of the pandemic, contributed about 5% of cases and nearly 40% of deaths. Residents and staff were prioritized for vaccination, but staff uptake, in particular, has remained low.
Dr. Berry will present on strategies to improve COVID-19 vaccine uptake, including data from IMPACT Collaboratory observational studies and a pragmatic trial.
The Joint Seminar Series on Clinical Trials in Aging is co-hosted by the Interventional Studies in Aging Center (ISAC) in the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife and the Brown University Center for Long-Term Care Quality & Innovation (Q&I). Lectures focus on issues in the design and execution of clinical trials, including trials currently in the field.
Thursday, May 27, 2021
12:00 – 1:00 pm ET
Zoom Details:
Join from PC, Mac, Linux, iOS or Android: https://hebrewseniorlife.zoom.us/j/89039784165
Or iPhone one-tap (US Toll): +14702509358,,89039784165# or +14703812552,,89039784165#
Dial-In: +1 470 250 9358 (US Toll) or +1 669 900 6833 (US Toll)
Meeting ID: 890 3978 4165
