What We Do

What We Do

The NIA IMPACT Collaboratory is a nationwide infrastructure funded through a cooperative agreement from the National Institute on Aging that promotes the conduct of embedded Pragmatic Clinical Trials (ePCTs) evaluating non-pharmacological approaches to care for people living with dementia (PLWD) and their caregivers within healthcare systems (HCSs).

The work of the IMPACT Collaboratory is accomplished by a coordinated effort of multidisciplinary experts from across the nation organized into 10 Working Cores Groups and Teams whose expert members partner with health care system leaders and key stakeholders to do the following:

  • Develop and disseminate technical, policy, and best practices guidelines for all aspects of conducting impactful, rigorous, ethically sound, and regulatory compliant ePCTs in partnership with the various HCSs that deliver care to PLWD and their caregivers.
  • Enhance research development and investigator capacity by:
    • Funding and guiding pilot ePCTs and providing the methodological and technical support needed to transform pilot studies into full-scale ePCTs.
    • Serving as a resource for NIA-funded investigators conducting ePCTs in PLWD.
    • Supporting the training of junior investigators to become experts in this field through the funding of career development awards, training workshops, and on-line training modules.
  • Engage stakeholders, including health care systems, to partner with researchers in the conduct of ePCTs in PLWD and their caregivers.


The work of the NIA IMPACT Collaboratory is anchored on 4 pillars:  knowledge generation, research development, training a workforce of investigators and stakeholder engagement