NEW FUNDING OPPORTUNITY: Request for Applications for the Pilot Grants Program Cycle 3B

Posted on by Erin Luers

Pilot Grant Program – Cycle 3B

The IMPACT Collaboratory is pleased to announce a Request for Applications for the Pilot Grants Program Cycle 3B.

In this cycle, the IMPACT Collaboratory will fund up to five one-year awards for pilot pragmatic clinical trials (ePCTs) that test non-pharmacological interventions embedded in health care system(s) for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners. Under this mechanism, interventions must be linked to the needs of a health care system (HCS). For more information, please see our Pilot Grants Program page.

The IMPACT Collaboratory will consider all applications for pilot ePCTs that evaluate non-pharmacological interventions to improve the care of people living with AD/ADRD and their care partners. However, this grant cycle will prioritize applications for interventions in these populations that aim to:

  • Improve care through behavioral economics “nudge” interventions;
  • Reduce inequities in health care;
  • Reduce potentially inappropriate medications through de-prescribing; or
  • Improve care in emergency departments.

The goal of the pilot studies is to generate the preliminary data necessary to design and conduct a future full-scale Stage IV effectiveness ePCT (based on the NIH Stage Model) funded through other grant mechanisms (NIH or other sources). Preference will be given to applications that address dementia care for populations traditionally marginalized or underrepresented in clinical trials and those that promote health equity.

All applications should make a convincing case that the pilot ePCT proposed can be scaled up to a full-scale, Stage IV effectiveness ePCT as the next step. It is anticipated that Pilot Studies will be funded for up to $175,000 in direct costs for a maximum of 12-months.

Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below.
  • Tuesday, August 23, 2021 at 2:00 pm ET: Registration closed.

Letter of Intent (LOI) Due – Required

Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis through:
  • September 17, 2021 @ 5pm ET

Full Proposals Due – By invitation only

Applications selected for further consideration will be invited to submit a full proposal due:
  •  January 14, 2022 @ 5pm ET

Read the full RFA here. Learn more about our previous Pilot Grant Awardees here.

If you have any questions regarding this funding opportunity, please refer to our Frequently Asked Questions or email IMPACTcollaboratory@hsl.harvard.edu.