Publications
Explore highlighted IMPACT Collaboratory publications below. To see all IMPACT Collaboratory publications and resources, or to conduct a detailed search, go to our Knowledge Repository.
- IMPACT Collaboratory Members Use Machine Learning to Reveal Hidden Treatment Effects in Gerontology Trials
- IMPACT Study Finds the Long-Term Data Cooperative to be a robust data resource for LTC Research
- IMPACT Collaboratory Demonstration Study Examines Champion-Led Deprescribing for People Living with Dementia in ACO Primary Care
- IMPACT Pilot Study Finds Dementia Care Navigation in Primary Care May Reduce Unmet Needs and Hospitalizations
- New Study Examines Housing Trends Among Older Adults with Cognitive Impairment
Housing characteristics of older adults with cognitive impairment
October 28, 2025
- IMPACT Pilot ePCT Study reveals limitations in using MDS Data to measure Distress in Nursing Home Residents living with dementia
- IMPACT Pilot Study Tests Deprescribing Approach for Older Adults with Dementia
- Study Authors Respond to Commentary on Hypoglycemia Monitoring in Long-Term Care
- New Study Highlights Gaps in Post-ED Follow-Up and Care Fragmentation Among Older Adults
- New Study Offers Practical Guidance for Using Baseline Outcome Measurements in SW-CRT Design
- IMPACT Pilot Study Highlights Limitations of EHR-Based Hypoglycemia Detection in Long-Term Care
- Demonstration Project results shared in new publication by Kern and team
- Career Development Awardee Kiselica captures enthusiasm for novel technology-based strategy
- Career Development Awardee Kiselica looks for nuance in equivocal trial results
- IMPACT research team explore relationship between Long COVID and prior vaccinations among people 66 and older
- Career Development Awardee Gettel and team explore caregiver healthcare use
- Patel Murali, Sadarangani and Brody explore opportunities to improve end-of-life dementia care
- Career Development Awardees Fabius and Sadarangani share perspectives on research gaps and opportunities to improve AD/ADRD care
- Career Development Awardee Frechman explores Epic End of Life Care Index as a predictive tool for older adults
- IMPACT Pilot study found both promise and challenge with cognitive impairment screening in the emergency department
- Career Development Awardee Patel Murali explores challenges related to complex care challenges of low-income adults in Medicaid supported assisted living
- IMPACT Pilot Awardee Carpenter explores barriers to telehealth program intervention for people living with dementia
- IMPACT Implementation team members review nonpharmacological pain management
- IMPACT Pilot Awardee Maust tests nudge intervention to reduce CNS-active polypharmacy
- IMPACT researchers explore approaches to dementia caregiver identification and recruitment
- Green explores the importance of communication in deprescribing efforts for people living with dementia
- IMPACT CDA Patel Murali and PCRO core member Carpenter explore comprehensive dementia care
- Li and Tong employ Bayesian model to correct for differential exclusion and ensure valid inferences in pragmatic clinical trials
Randomized in error in pragmatic clinical trials
January 1, 2025
- IMPACT authors explore goals and concerns of older adults during emergency department visits
- Pajewski among researchers employing a machine-learning model using electronic health data to predict cognitive impairment and dementia following an episode of critical illness
- Research explores demographic variations in completing COVID-19 vaccine series
- IMPACT CDA Kiselica describes benefits and risks of reliance on digital technologies in caring for people living with dementia
- IMPACT CDA Tina Sadarangani and team examine acceptability of CareMOBI with primary care providers
- Authors share results of survey of clinical neuropsychologists’ reactions to Alzheimer’s Association workgroups draft criteria for Alzheimer’s disease
- IMPACT CDA Gettel determines that emergency department use peaks before and after dementia diagnosis
- IMPACT CDA Kiselica examines technology-based instrumental activities of daily living for people with ADRD
- IMPACT authors provide insights into methodology for small-scale stepped wedge cluster randomized trials
- IMPACT CDA Douglas finds it is feasible to implement Dementia Collaborative Coaching into routine workflows of speech-language pathologists working in nursing homes
- IMPACT CDA Sadarangani explores use of communication app with family caregivers of people living with dementia
- Karlawish calls for the breaking of tyranny of treatment and prioritization of patient-centered care
Alzheimer’s disease biomarkers and the tyranny of treatment
October 3, 2024
- IMPACT HCS Scholar Lum describes OurNotes adaptation to clarify whether the author is the patient, the patient with help, or a nonpatient
- Pajewski highlights links between socioeconomic and medical determinants of subjective cognitive decline in US
- IMPACT members describe pragmatic approach to identifying goal-concordant care for nursing home residents with ADRD
- New study explores inequities in testing and infection of COVID-19 variants of concern
- IMPACT Engaging Partners Team describes the movement away from use of the word stakeholder in new publication
- Kiselica and team explore variability within a neurocognitive test battery as indicator of cognitive dysfunction
- IMPACT member Allore among authors of paper on longitudinal patterns of blood pressure and dementia risk
- IMPACT Demonstration Project Awardee publishes results of survey measuring perceptions of care coordination and adverse events among people living with dementia
- New Mobile Tool for Measuring Subjective Cognitive Decline Shows Promise
- Pilot Awardee Gabbard publishes results paper
- IMPACT Awardee Forester Publishes Results of Pilot Study on Dementia Care Training for Nurse Care Managers
- Daily care hours among caregivers of older emergency department patients with dementia and undiagnosed cognitive impairment
- Career Development Awardee Juckett publishes article on supporting mealtime participation among community-dwelling people living with dementia
- IMPACT authors examine emotion regulation in people living with dementia and their care partners
- Leaders of the NIA IMPACT Collaboratory reflect on the first five years and look to a future of improved dementia care through ePCTs in recent article in Generations Journal, Summer 2024 edition
- IMPACT authors examine ethical value of consulting community members in non-emergency trials with waivers of informed consent
- Loneliness and global cognitive functioning in racially and ethnically diverse US midlife and older adults
- Better Conversations for Better Informed Consent: Talking with Surgical Patients
- New publication on enhancing equity in health research with Indigenous communities
- IMPACT PCRO Core members compare dementia diagnoses and cognitive function measures in Medicare claims and MDS
- IMPACT authors review linear mixed models for stepped-wedge cluster randomized trials
- Commentary highlights IMPACT framework designed to provide health equity in dementia care
- IMPACT researchers explore differences in COVID-19 vaccine brand usage by rural/urban demographics
- IMPACT Design and Statistics Core members consider the two-treatment two-period cluster randomized crossover design
- Focus group study finds that dementia educational materials should be clear and direct
- IMPACT author explores the pros and cons of using digital technologies to assist PLWD
- Research by team including IMPACT members Vince Mor and Ellen McCarthy explores the varied uptake of the coadministered COVID/influenza vaccines during the pandemic
COVID-19 and influenza vaccine coadministration among older U.S. adults
February 23, 2024
- Evidence Map of Non-Pharmacological Dementia Care Partner Interventions Implemented in the US: Gaps and Impact Opportunities
- Considerations When Designing and Implementing Pragmatic Clinical Trials That Include Older Hispanics
- Best Practice Recommendations for Integrating Health Equity into Pragmatic Clinical Trials for Dementia Care
- Ready or Not: A Conceptual Model of Organizational Readiness for Embedded Pragmatic Dementia Research
- Medication regimen complexity among community-dwelling older adults with incident mild cognitive impairment or dementia
- Study shows that pharmacist-led deprescribing via telehealth can reduce burden on PLWD
- Using mHealth to Improve Communication in Adult Day Services Around the Needs of People With Dementia: Mixed Methods Assessment of Acceptability and Feasibility
- Care partners and consumer health information technology: A framework to guide systems-level initiatives in support of digital health equity
- Leaders of the NIA IMPACT Collaboratory celebrate its first five years in JAGS Special Issue
- IMPACT investigator publishes results of first known study to provide methods for calculating normed scores for cognitive dispersion indices among older adults
- New horizons in frailty identification via electronic frailty indices: early implementation lessons from experiences in England and the United States
- IMPACT members Douglas and Carpenter author paper on staff perspectives on dementia care in nursing homes
- Sliding Scale Insulin Use in Nursing Homes Before and After Onset of the COVID-19 Pandemic
- Authors call for national conversation on health care fragmentation, continuity and coordination
- IMPACT authors explore inequities in Alzheimer’s and dementia care treatment
- The Technology in Caring Questionnaire: Development and Psychometric Properties
- Diagnostic Uncertainty and Decision-Making in Home-Based Primary Care: A Qualitative Study of Antibiotic Prescribing
- IMPACT authors explore ethical challenges of using algorithms for dementia diagnosis
- Anesthesiologists’ Attitudes Toward Randomization to General versus Neuraxial Anesthesia for Cesarean Delivery
- “A Raw Blessing” – Caregivers’ Experiences Providing Care to Persons Living with Dementia in the COVID-19 Pandemic
- IMPACT Collaboratory funds two Career Development Awards
The National Institute on Aging (NIA) Imbedded Pragmatic AD/ADRD Clinical Trials (IMPACT) Collaboratory is pleased to announce the recipients of the 2023 Career Development Award Program. Recipients were selected from an impressive group of competitive applications.
About the IMPACT Collaboratory Career Development Award Program
NIA IMPACT Collaboratory funds two to three Career Development Awards (CDAs) annually. These awards support the development of early-stage MD, PhD, or equivalent researchers who seek careers conducting ePCTs for people living with AD/ADRD and their care partners. This mechanism funds research projects that are preparatory to conducting a future ePCT such as secondary data analysis, intervention ...
- Implementing Dementia Caregiver Programs in Real-World Settings: Fidelity Considerations
- Design and Statistics core members review recent publications for adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials
- IMPACT members explore partnering with social service staff on ePCTs
- Article highlights IMPACT iLibrary of potential outcomes measures
- Article looks at demential care trials in community-based settings and Medicaid home
- Supplemental NIA IMPACT study with pharmacies results in national database of older adult COVID-19 vaccine data
Data Resource Profile: COVid VAXines Effects on the Aged (COVVAXAGE)
October 18, 2023
- Preliminary Evidence for Dementia Collaborative Coaching
Preliminary Evidence for Dementia Collaborative Coaching
October 10, 2023
- Recent IMPACT team article describes formal methods for sample size and power analyses for testing subgroup-specific treatment effects in parallel-arm CRTs
- New article highlights how IMPACT Lived Experience Panel contributes to improving ePCTs in dementia care
- Authors comment on antibiotic use considerations for patients receiving end-of-life care
- Home care offers lessons to address challenges and opportunities in information sharing in elder care
- IMPACT authors assert that funding early-career researchers is vital to improving dementia care
- IMPACT members explore statistical trial issues for cardiovascular issues and dementia
- Team of IMPACT members address health equity and ePCT readiness in dementia care
- Article explores patient and public involvement in pragmatic trials
- Prioritizing Community-Based Care for People With Alzheimer’s Disease and Related Dementias in Ethnically Diverse Communities
- Using Hybrid Effectiveness Studies to Facilitate Implementation in Gerontology: Three Case Studies in Dementia Care Research
- IMPACT member investigates informal caregivers’ struggles with dementia symptom management and provider support
- IMPACT members assess booster vaccine uptake in older adults
- IMPACT members explore risk for depression among family caregivers
- IMPACT supplement awardees publish article analyzing the risks of COVID-19 vaccination in older adults
- IMPACT member leads hospice/palliative care survey in NY State to inform nursing school education
- The Role of Place in Person- and Family-Oriented Long-Term Services and Supports
- IMPACT members publish article on evaluating the pragmatic characteristics of advance care planning outcome measures in dementia clinical trials
- A survey of neuropsychological assessment feedback practices among neuropsychologists
- Study explores how clinicians approach patient enrollment in pragmatic randomized trials
- Article explores how to protect older adults while transitioning from emergency department to community care
- IMPACT members discuss framework to include Hispanic/Latinos in ADRD clinical trials
- Article reviews relationship between vaccines and COVID-19 breakthrough infections
- IMPACT members explore how algorithms using electronic health records can identify patients with Alzheimer’s disease or related dementias
- Study explores telehealth use by people living with dementia and their caregivers during the pandemic
- Article examines antimicrobial resistance in homebound seniors using national samples to address UTIs in PLWD
- Article provides instruction on how to best design longitudinal cluster randomized trials
- IMPACT member publishes article on nursing home regulations and the pandemic
- IMPACT members recommend a risks-based approach for end-of-life care patients participating in pragmatic clinical trials
- It’s more than language: cultural adaptation of a proven dementia care intervention for Hispanic/Latino Caregivers
- A methodological review found that randomization is often fragile in Stepped-Wedge Cluster Randomized Trials
- Article explores pandemic affects on skilled nursing facility care
- Understanding the Questions of Race and Ethnicity during a Home Visit
- IMPACT-C investigators find COVID-19 testing and vaccination differences across nursing home staff shifts
- A Scoping Review of Telehealth Palliative Care Interventions in Nursing Homes: Characteristics and Outcomes
Telehealth Palliative Care in Nursing Homes: A Scoping Review
February 6, 2023
- IMPACT members share approaches to promote health equity in pragmatic trials in ADRD
- IMPACT member joins co-authors in recommending reporting transparency related to volunteer dementia care trial
Open science in dementia care embedded pragmatic clinical trials
February 1, 2022
- IMPACT funded investigators are among team discussing opportunities to improve ADRD care through consumer-oriented health information in LHSs
- IMPACT members demonstrate impact of dementia care training on nurse care managers’ interactions with family caregivers
- IMPACT members publish results of study on aging couples’ cognition and depressive symptoms over time
- Sadarangani among authors introducing new application aimed at facilitating information exchange between primary care providers and adult day centers
- IMPACT members discuss applying power analyses for stepped wedge design with multivariate continuous outcomes
- Niznik and co-authors examine deprescribing medications for those with dementia near the end of life
- Taljaard co-authors article exploring under- and over-recruitment in pragmatic trials
- Mor contributes to publication that explores effectiveness of COVID-19 vaccine boosters in nursing home residents
- JAGS article analyzes gap in guidance for cluster randomized trials involving PLWD in LTC homes
- IMPACT members share considerations for ePCTs of advance care planning interventions for PLWD into real-world settings
- Taljaard co-authors article addressing heterogeneity in trials and how to manage its effects
Heterogeneity in pragmatic randomized trials: sources and management
October 22, 2022
- Gabbard lead author on article examining engaging end users in design of patient portal advance care planning
- JAMDA article describes innovation of the LTC Data Cooperative
- IMPACT members co-author article analyzing imputation methods for managing missing study data
- IMPACT funded investigators author article on infectious diseases in PLWD
- IMPACT HET member among authors of article on secondary caregiver effects by gender and race
- Study looks at dementia patient outcomes for those receiving Medicaid Home and Community-Based Services in Maryland
- Fazio and Zimmerman author editorial on importance to developing dementia outcome measures
- IMPACT COVID-19 Supplement investigators find effectiveness of a second vaccine booster dose against infection, hospitalization, or death among nursing home residents
- IMPACT members find critical barriers among care partners and older adults with cognitive impairment during emergency department care transitions
- IMPACT-funded trial aimed at de-prescribing inappropriate medication use in PLWD with the help of clinician champions
- IMPACT leaders are among authors of article exploring the role of primary care providers in cognitive decline detection
- National Cohort Study of Homebound Persons Living with Dementia: Antibiotic Prescribing Trends and Opportunities for Antibiotic Stewardship
- Travers, Gifford and Baier co-author qualitative study on providers’ perspectives on high-quality dementia care
Providers’ Perspectives on High-Quality Dementia Care in Long-Term Care
September 2, 2022
- Mor and Berry co-author article on testing type differences in skilled nursing facilities
- IMPACT members examine use of the label “pragmatic” in clinical trials and determine that its use is not useful
- IMPACT members publish article assessing COVID-19 multicomponent infection control intervention
- Mor and White examine incidence and outcomes of COVID-19 in nursing home care
- Study how vaccine mandates affected nursing home staff shortages co-authored by IMPACT funded investigator
- Mor co-authors article examining the effect of race and dementia prevalence on COVID-19 infection control in nursing homes
- Authors help identify levels of medical complexity for patients living with dementia in adult day centers
- IMPACT posdoc part of team proposing partnerships between High Income and Low-/Middle-Income countries to speed aging interventions
- Li and Talijaard co-author article on sample size calculators for planning stepped-wedge cluster randomized trials
- McCarthy and Bynum publish article to inform tradeoffs of approaches to test validity of Medicare claims-based algorithms
- Taljaard and Li co-author article on power analysis for cluster randomized trials with continuous coprimary endpoints
- Li, Taljaard, Hey, and Mitchell publish literature review of ethics in trials involving PLWD
- Berry co-authors AJPH article examining COVID-19 vaccine mandates for nursing home staff in Mississippi
- Pragmatic clinical trial design in emergency medicine: Study considerations and design types
- Largent examines investigators’ obligations to patient-subjects in ePCTs
- IMPACT members co-author study of COVID-19 vaccine hesitancy in healthcare assistants
- White, Gutman, and Mor publish research on adverse effects of COVID-19 vaccine booster in nursing home residents
- McCarthy co-authors article examining whether patients with dementia have increased risk of adverse outcomes after discharge
- Zimmerman Lead Author on Recommendations from a NIH conference
- IMPACT Members Co-Author Article Addressing Implementation and Dissemination Challenges and Opportunities
- IMPACT Members Co-Authors on Article Addressing Research Challenges and Potential Solutions from NIA Consensus Conference
- Aranda co-authors article examining how neuropsychiatric symptoms can affect caregiver relationships in Mexican Americans
- Hwang among authors considering how to include older adults in emergency department research
- Mor and co-author encourage the use of large pragmatic trials to test anti-amyloid therapies for Alzheimer’s disease
- Gitlin co-authors systematic review to assess effectiveness of educational interventions for formal caregivers
- IMPACT members co-author article evaluating whether impact of vaccination campaigns in skilled nursing facilities
- Taljaard Contributes to Publication on Challenges Distinguishing Randomized Trials for Meta-Research
- Gaugler and Gitlin co-author article exploring how Critical Race Theory can be used in recruitment of Black participants in ADRD research
- IMPACT members publish qualitative analysis of communication workflows between adult day service centers and primary care providers
- Review of pragmatic trials finds multiple primary outcomes are common but also identifies need for improved transparency in co-primary outcomes
- IMPACT members among authors of a recent publication describing reporting of informed consent information in pragmatic trial reports
- IMPACT members address methodological challenges in pragmatic trials in Alzheimer’s disease and related dementias in new journal article
- IMPACT researchers provide insight into facility-level strategies to increase vaccine uptake among nursing home staff
- IMPACT members co-author article summarizing barriers to identifying people with ADRD
- Nonpharmacologic interventions for family caregivers of people living with dementia in Latin-America: A scoping review
- IMPACT members publish article on sample size considerations for stepped wedge designs with subclusters
- Berry co-authors article to COVID-19 vaccine response among healthcare workers and nursing home residents
- Mor co-authors systematic review of long-term care facility characteristics associated with COVID-19 outcomes
- Gaugler, Gitlin, and Zimmerman write editorial on “Aligning Dementia Care Science With the Urgent Need for Dissemination and Implementation”
- White authors commentary on study examining underreporting of early nursing home COVID-19 data
- Karlawish and Grill co-author article considering ethical guidance for clinical trials in neurodegenerative disease
- Niznik and Hanson among authors of publication analyzing incidence of deprescribing bisphosphonates among nursing home residents with dementia
- IMPACT researchers examine racial and ethnic disparities in vaccine acceptance among nursing home staff and residents
- Gutman and Mor co-author article comparing adverse events follow one dose of COVID-19 vaccination among nursing home residents
- IMPACT members co-author publication analyzing a national survey of perceptions of COVID-19 vaccines among healthcare assistants
- Chodosh co-authors study of barriers and facilitators to vaccination for people with Parkinson’s Disease
- Zimmerman publishes editorial advocating that clinicians consider five critical issues for research measurements
What Clinicians Need to Know About Measurement
July 29, 2021
- Mor and White write correspondence to the editor of the NEJM regarding IMPACT-C supplement study
- Bynum, Travison, and Mor co-author article summarizing presentations from 2020 Dementia Care, Caregiving, and Services Research Summit
- Emerging topics in dementia care and services
Emerging topics in dementia care and services
July 10, 2021
- Aranda and Hinton explore impact of dementia from 2020 National Research Summit
- Karlawish contributes to review article on research participation by persons living with dementia and their caregivers
- Taljaard authors paper on unique considerations for pilot and feasibility studies for pragmatic trials
- Karlawish writes commentary considering how creative care can be used in treating people with dementia
- Sadarangani and Travers are authors on editorial on engaging CNAs to enhance COVID-19 vaccine receptivity
- Van Haitsma co-authors article discussing the state of research on workforce development in dementia care
- Mor contributes to publication providing evidence of COVID-19 vaccine effectiveness in a real-world nursing home setting
- Hey co-authors magazine article examining the paradox of evidence-based decision making
- Hey and Taljaard co-authors on review of pragmatic clinical trials
- IMPACT members co-author article sharing lessons learned from nursing home staff on COVID-19 vaccine hesitancy
- Harrison, Mor and Gifford co-author article examining vaccine hesitancy among staff in skilled nursing facilities
- IMPACT researchers examine systematic approach to address advance care planning during COVID-19 pandemic
- Laura Gitlin and Nancy Hodgson author chapter on family care programs
- Sadarangani among authors of publication on consequences of adult day centers closing due to COVID-19 and the factors supporting their resiliency
- Largent and Karlawish authors on a publication discussing the future of p-Tau and Alzheimer’s disease blood tests
- IMPACT leaders reflect on article collection of interdisciplinary approach to dementia
Reflections on the IJHPR’s article collection on dementia
October 6, 2020
- IMPACT members discuss the importance of comprehensive dementia care
Editorial: How Do We Make Comprehensive Dementia Care a Benefit?
September 25, 2020
- Hodgson and Hanson co-author article describing alternative consent models in pragmatic palliative care clinical trials
- Quiñones and Allore are authors on a paper addressing multimorbidity and racial and ethnic disparities in ADRD
- Statewide effort to reduce COVID-19 infections could be used as model for national effort
Stemming the Tide of COVID-19 Infections in Massachusetts Nursing Homes
September 15, 2020
- Gitlin and Gaugler contribute to “Application of randomization techniques for balancing site covariates in the adult day service plus pragmatic cluster-randomized trial”
- JAGS article studies national trends in potentially preventable hospitalizations of older adults with dementia
- Karlawish and Hoffman call for reconsidering visitor bans in long-term care facilities
- IMPACT Technical Data Core members explore diagnosed prevalence of Alzheimer’s disease and related dementias in Medicare Advantage plans
- JAGS Special Issue: Statistical Considerations for Embedded Pragmatic Clinical Trials in People Living with Dementia
- JAGS Special Issue: Engaging Stakeholders in the Design and Conduct of Embedded Pragmatic Clinical Trials for Alzheimer’s Disease and Alzheimer’s Disease–Related Dementias
- JAGS Special Issue: Selecting Outcomes to Ensure Pragmatic Trials Are Relevant to People Living with Dementia
- JAGS Special Issue: Using Healthcare Data in Embedded Pragmatic Clinical Trials among People Living with Dementia and Their Caregivers: State of the Art
- JAGS Special Issue: Transforming Dementia Care Through Pragmatic Clinical Trials Embedded in Learning Healthcare Systems
- JAGS Special Issue: Ethical and Regulatory Issues for Embedded Pragmatic Trials Involving People Living with Dementia
- JAGS Special Issue: Dissemination and Implementation of Evidence-Based Dementia Care Using Embedded Pragmatic Trials
- JAGS Special Issue: Training the Workforce to Conduct Embedded Pragmatic Clinical Trials to Improve Care for People Living with Dementia and Their Caregivers
- JAGS Special Issue: Building a National Program for Pilot Studies of Embedded Pragmatic Clinical Trials in Dementia Care
- JAGS Special Issue: Achieving Health Equity in Embedded Pragmatic Trials for People Living with Dementia and Their Family Caregivers
- JAGS Special Issue: Embedded Pragmatic Trials in Dementia Care: Realizing the Vision of the NIA IMPACT Collaboratory
