February 5, 2023
IMPACT members Katherine D. Peak, MPH, Fan Li, PhD, Susan L. Mitchell, MD, MPH, Ana R. Quiñones, MD, MS, and Monica Taljaard, PhD are among authors of an article on health equity considerations in pragmatic trials involving people living with dementia in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring. Investigators reviewed 62 pragmatic trials of people with dementia published between 2014 and 2019. They concluded that ongoing and future pragmatic trials should more rigorously integrate equity considerations into their design, conduct, and reporting.
Abstract
To improve dementia care delivery for persons across all backgrounds, it is imperative that health equity is integrated into pragmatic trials. 62 pragmatic trials of people with dementia published 2014 to 2019 were reviewed. Investigators assessed health equity in the objectives; design, conduct, analysis; and reporting using PROGRESS-Plus which stands for Place of residence, Race/ethnicity, Occupation, Gender/sex, Religion, Education, Socioeconomic status, Social capital, and other factors such as age and disability.
Highlights
- Few pragmatic trials are explicitly designed to inform equity-relevant objectives.
- Few pragmatic trials take steps to increase enrollment from equity-relevant groups.
- Disaggregated results across equity-relevant groups are seldom reported.
- Adherence to existing tools (e.g., IMPACT Best Practices, CONSORT-Equity) is key.
Read the full article with this link.