Notice of Intent (NOI) to Publish a New Funding Opportunity for the IMPACT Demonstration Project Program

Demonstration Project Grants Cycle 2

We are pleased to announce that the NIA IMPACT Collaboratory plans to publish a Request for Applications (RFA) for Demonstration Project Grants on October 4, 2021. Letters of Intent are required and due no later than October 29, 2021.

IMPACT will fund Demonstration Projects (maximum duration 24 months) designed as full-scale, Stage IV effectiveness embedded pragmatic clinical trials (ePCT) (based on the NIH Stage Model) that test, measure and evaluate the effect of a care delivery intervention program in a health care system for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners.

The intervention will typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Demonstration Projects will allow health care systems and investigators to gain real-world experience integrating pragmatic non-pharmacologic interventions into usual clinical workflow and health care delivery practices in a controlled manner that provides clear information on the impact of the intervention program. Under this mechanism, interventions must be linked to the needs of a health care system.

The goal of the Demonstration Project is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems. The IMPACT Collaboratory will give preference to applications that address dementia care for populations historically marginalized or underrepresented in clinical trials and those that promote health equity. It is anticipated that Demonstration Projects will be funded for up to $500,000 in direct costs for a maximum of 24-months.

Stay tuned for updates regarding the release of the RFA, an informational webinar and application deadline. Visit IMPACTcollaboratory.org to learn more about the Demonstration Projects Grants Program and currently awarded grants. If you have questions related to this funding opportunity, please contact IMPACTcollaboratory@hsl.harvard.edu.