The IMPACT Collaboratory is pleased to announce a Request for Applications (RFA) for the second cycle of the Demonstration Project Program.
IMPACT will fund up to two Demonstration Projects (maximum duration 24 months) designed as full-scale, Stage IV effectiveness embedded pragmatic clinical trials (ePCT) (based on the NIH Stage Model) that test, measure and evaluate the effect of a non-pharmacological care delivery intervention program in a health care system for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners. The goal of the Demonstration Project is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.
Under this mechanism, interventions must be linked to the needs of the health care system. Suitable interventions typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Demonstration Projects will allow health care systems and investigators to gain real-world experience integrating pragmatic non-pharmacological interventions into usual clinical workflow and health care delivery practices in a controlled manner that provides clear information on the impact of the intervention program.
The IMPACT Collaboratory will only fund Demonstration Project applications that include a clinical trial as defined by the National Institutes of Health. Preference will be given to applications that address dementia care for populations historically marginalized or underrepresented in clinical trials and those that promote health equity.
It is anticipated that Demonstration Project awards will be for up to $500,000 in direct costs for a maximum of 24-months and will be non-renewable.
Learn more about the Demonstration Projects Program here.
Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below.
Tuesday, October 19, 2021 at 1:00 pm ET: Registration closed.
Letters of Intent (LOI) by Email – Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis through:
October 29, 2021 @ 5pm ET
Full Applications Due – By invitation only
Applicants selected for further consideration will be invited to submit a full application due:
January 14, 2022 @ 5pm ET
Read the full RFA here. Learn more about our previous Demonstration Project Awardees here.
If you have any questions regarding this funding opportunity, please refer to our Frequently Asked Questions or email IMPACTcollaboratory@hsl.harvard.edu.
Please help to publicize this IMPACT funding opportunity and encourage investigators and colleagues to apply.