Join us for IMPACT Grand Rounds on Thursday, September 21 at 12pm ET with Dr. James Flory who will be presenting on the “Decision Architecture Randomization Trials: Extremely Low-Cost Trials with Preservation of Clinician and Patient Choice.”

Dr. James Flory is an endocrinologist and clinical epidemiologist at Memorial Sloan Kettering Cancer Center, specializing in the management of hyperglycemia and diabetes in cancer patients. Dr. Flory’s research career began with a pre-doctoral fellowship in bioethics at the NIH, where his work on ethical and logistical challenges to traditional randomized controlled trials led him to become very interested in alternative clinical research approaches, especially observational studies. Much of his subsequent career has focused on the application of observational study methodologies to answer comparative effectiveness questions, supported by funding from AHRQ, NIH, and PCORI. His research has largely focused on diabetes care, particularly around metformin use, and he was part of a successful effort to revise the Food and Drug Administration (FDA) label for metformin to make it accessible to hundreds of thousands of patients for whom it had been inappropriately contraindicated. In recent years, Dr. Flory’s research has increasingly focused on the intersection of diabetes and cancer treatment, with a particular focus on supportive care in patients with hyperglycemia in the setting of breast and pancreatic cancer. His major research focus now is a PCORI-funded methods development project to work on a novel pragmatic trial design called a Decision Architecture Randomization Trial (DART). DART is intended to permit extremely efficient, low-cost, and safe studies of clinical comparative effectiveness questions that would not be likely to attract the resources needed for a traditional clinical trial.

Zoom Conferencing
Join from PC, Mac, iOS or Android: https://hebrewseniorlife.zoom.us/j/97344810673
Dial-In:  +1 312 626 6799 (US Toll) or  +1 470 250 9358 (US Toll)
Meeting ID:  973 4481 0673

PDF Flyer: IMPACT GR | J. Flory – 9.21.23