The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is pleased to announce a Request for Applications for the Pilot Grants Program Cycle 5A.
In this cycle, the IMPACT Collaboratory will fund up to five 1-year awards for pilot pragmatic clinical trials (ePCTs) that test non-pharmacological interventions embedded in health care system(s) for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners. All applications should make a convincing case that the pilot ePCT proposed can take the next step to a full-scale Stage IV effectiveness ePCT, as defined by the National Institutes of Health (NIH). It is anticipated that Pilot Studies will be funded for up to $200,000 in direct costs for a maximum of 12-months (direct costs were raised from $175,000 to $200,000). Applicants from under-represented racial and ethnic groups as well as individuals with disabilities are strongly encouraged to apply for funding. For more information, please see our Pilot Grants Program page.
All applications for pilot ePCTs that evaluate non-pharmacological interventions to improve the care of people living with AD/ADRD and their care partners will be considered. However, this grant cycle will prioritize applications for interventions in these populations that aim to:
- Improve care through behavioral economics “nudge” interventions;
- Reduce inequities in health care;
- Reduce potentially inappropriate medications through de-prescribing; or
- Improve care in emergency departments.
The goal of the pilot projects is to generate the preliminary data necessary to design and conduct a future full-scale Stage IV effectiveness ePCT (based on the NIH Stage Model) funded through other grant mechanisms (NIH or other sources). Preference will be given to applications that address dementia care for populations traditionally marginalized or underrepresented in clinical trials and those that promote health equity.
Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below.
Tuesday, February 14, 2023, at 12:00pm ET: Registration closed.
Letters of Intent (LOI) – Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis through:
March 3, 2023 @5PM ET
Full Proposals (By invitation only)
Applications selected for further consideration will be invited to submit a full proposal due:
June 16, 2023 @ 5pm ET