The mission of the National Institute on Aging (NIA) IMbedded Pragmatic Alzheimers disease (AD) and AD Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is build the nation’s capacity to conduct pragmatic clinical trials of interventions embedded within health care systems for people living with dementia and their caregivers.

The IMPACT Collaboratory accomplishes this mission by:

  • Developing and disseminating best practice research methods
  • Supporting the design and conduct of pragmatic trials, including pilot studies
  • Building investigator capacity through training and knowledge generation
  • Catalyzing collaboration among stakeholders, healthcare providers, and investigators
  • Ensuring the research includes culturally-tailored interventions and people from diverse and under-represented backgrounds


To transform the delivery, quality, and outcomes of care provided to Americans living with dementia and their caregivers by accelerating the testing and adoption of evidence-based interventions within healthcare systems.

core values

Be Collaborative

Create and integrate a community of researchers, health system providers and stakeholders

Be Excellent

Promote the highest quality research and integrity among investigators

Be Generative

Serve as catalyst for novel ideas and cultivate a diverse cadre of trained investigators

Be Transformative

Develop and test interventions embedded in real-world healthcare systems that will make a difference in lives of persons with dementia and their families

Be Sustainable

Establish a durable research infrastructure and knowledge base

Be Inclusive

Ensure research includes and is applicable to persons of all backgrounds