Causal Inference in Pragmatic Trials

March 2023 – In Grand Rounds 35, Dr. Eleanor "Ellie" Murray explores causal inference in randomized pragmatic trials highlighting topics such as immortal time bias, per-protocol effects, and how to use the SMARTER acronym when thinking about causal research questions.

Speaker

Eleanor Murray, PhD

Assistant Professor
Epidemiology

Boston University School of Public Health
@EpiEllie

Learning Objectives

  • Discuss the properties of a good causal research question.
  • Identify two key sources of potential bias common in pragmatic trials.
  • Recognize pragmatic trial scenarios requiring sophisticated causal inference statistical methods.