IMPACT members Kathleen Unroe, MD, MHA, MS, Debra Saliba, MD, MPH, Sheryl Zimmerman, PhD and Jerry Gurwitz, MD, contribute commentary in the Journal of the American Geriatrics Society citing IMPACT and the Long Term Data Cooperative as National Institute on Aging (NIA) initiatives that provide foundational work addressing the identification and capture of important clinical outcomes, laying the groundwork for a nursing home clinical trials network. The commentary is based on the article Evaluation of medical therapies in the nursing home population: Gaps, challenges, and next steps.