Lessons From the First Decade of the NIH Pragmatic Trials Collaboratory

February 2022 – In Grand Rounds 24, Drs. Hernandez, Curtis and Weinfurt, the Principal Investigators of the NIH Pragmatic Trials Collaboratory, describe how the Collaboratory began ten years ago, the current state of their research, and where they see the research going in the future.

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Adrian Hernandez, MD, MHS

Adrian Hernandez, MD, MHS
Executive Director,
Duke Clinical Research Institute
Vice Dean, Duke University School of Medicine

Leslie Curtis, PhD

Leslie Curtis, PhD
Professor and Chair
Department of Population Health Sciences
Duke School of Medicine
Faculty member, Duke Clinical Research Institute

Kevin Weinfurt, PhD

Kevin Weinfurt, PhD
Professor and Vice Chair of Research
Department of Population Health Sciences
Duke University Medical Center
Faculty member, Duke Clinical Research Institute

Learning Objectives

  • Understand the goals of the NIH Pragmatic Trials Collaboratory
  • Describe the state of the science of pragmatic trials based on experiences from the Collaboratory’s first decade
  • Identify opportunities for advances in pragmatic trials methodology