The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore challenges and opportunities in using electronic health records (EHRs) in pragmatic clinical trials. The series will highlight advances in digital health, new approaches and evolving standards for EHRs, and implications for researchers conducting pragmatic ...

The NIH Health Care Systems Research Collaboratory recently released a summary of a 2019 comprehensive workshop to explore and discuss statistical issues encountered with embedded pragmatic clinical trials (ePCTs). The new Workshop Summary describes panel discussions with the principal investigators and statisticians of NIH Collaboratory Demonstration Projects and the challenges and solutions encountered during the ...

The National Institute on Aging (NIA) IMbedded Pragmatic Alzheimer’s disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory has released two new funding opportunities available for investigators interested in developing embedded pragmatic clinical trials in dementia research. In support of our mission, the IMPACT Collaboratory is requesting applications for the Pilot Grant Award and ...

On April 15 2020, the National Academies’ Committee on Care Interventions for Individuals with Dementia and Their Caregivers hosted a virtual public workshop. This workshop brought together key stakeholders and experts to provide input to the committee on a draft Agency for Healthcare Research and Quality (AHRQ) systematic review that examines existing evidence on care ...

We are pleased to share a new report from the IMPACT Stakeholder Engagement Team, led by Gary Epstein-Lubow, MD and Katie Maslow, MSW, regarding stakeholder research priorities. This report is a compilation of work beginning with input from the NIA IMPACT Collaboratory’s Stakeholder Advisory Committee and then finalized after additional Stakeholder Engagement Team discussion during and following ...

The latest blog post from Keith Goldfeld, DrPH, MS, MPA, member of the executive committee of the IMPACT Collaboratory Design and Statistics Core, discusses how the design effect could provide additional insight into cluster randomized trials in his most recent blog post. The ideas in this blog post were motivated in part by Goldfeld’s work ...

The Tailored Activity Plan (TAP),  a home-based occupational therapy intervention shown to reduce behavioral symptoms in people living with dementia and caregiver burden, was recently included in an article in the Wall Street Journal. The TAP program was developed by Laura Gitlin, PhD, FGSA, FAAN, Dean and distinguished professor at College of Nursing and Health ...

Keith Goldfeld, DrPH, MS, MPA, member of the executive committee of the IMPACT Collaboratory Design and Statistics Core, recently discussed his work with the IMPACT Collaboratory on his blog, ouR data generation. Goldfeld wrote about how to analyze data from a stepped-wedge designed cluster randomized trial. He said that this design can be an important tool ...

NIA IMPACT Collaboratory multiple principal investigator Susan Mitchell, MD, MPH, spoke at the February 4 Palliative and Advanced Illness Research (PAIR) Center Series at the Perelman School of Medicine at Pennsylvania University. Her talk, “Advanced Dementia: The Evolution of Research Informing Practice,” included a look at the overall body of work in advanced dementia and ...

, Executive Director for the IMPACT Collaboratory at Brown University, authored a blog post for AcademyHealth describing the need for embedded pragmatic clinical trails and how the IMPACT Collaboratory can help. Harrison describes the rise in diagnoses of Alzheimer’s disease and related dementias as a global public health crisis and describes how embedded pragmatic clinical trials ...