The IMPACT Collaboratory will have a strong presence at the upcoming Alzheimer’s Association International Conference (AAIC). The presentation, “NIA IMPACT Embedded Pragmatic Clinical Trials for the Improvement of Care for People Living with Dementia and their Care Partners” includes modules by IMPACT members: Vince Mor, Laura Hanson, Jason Karlawish, and Fan Li and will be ...

The National Institute on Aging (NIA) is holding a virtual summit series, “2020 National Research Summit on Care, Services, and Supports for Persons with Dementia and Their Caregivers.” Held over 3 days, the summit series provides an opportunity for researchers and stakeholders to discuss the current research environment, gaps, opportunities and priorities for future dementia ...

Kathleen Unroe, MD, MHA from the IMPACT Pilot Studies Core recently co-authored an editorial published in the Journal of the American Geriatrics Society. In it, they stated the benefits of collaboration between health systems and nursing facilities. The editorial, “Time to Leverage Health System Collaborations: Supporting Nursing Facilities Through the COVID-19 Pandemic,” was written in response ...

Members of the IMPACT Collaboratory co-authored an opinion piece in the Washington Post calling for long-term care facilities to reconsider visitor bans. Jason Karlawish, MD, Core Leader of the IMPACT Ethics and Regulation Core and Allison K. Hoffman, JD, a member of the core’s executive committee, joined David C. Grabowski, PhD to author the editorial. They ...

Members of the IMPACT Collaboratory Technical Data Core recently published new findings in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring from the Alzheimer’s Association. The study is the first to report the prevalence of Alzheimer’s disease and related dementias (AD/ADRD) diagnosis among Medicare Advantage (MA) beneficiaries immediately prior to and following the transition from ...

IMPACT Multiple Principal Investigators Susan Mitchell, MD, MPH and Vince Mor, PhD were panelists in the “Workshop on Nursing Home, Hospice, and Palliative Care for Individuals with Later-Stage Dementia: Making Health Systems More Responsive to Dementia.” Workshop Details: https://www.nationalacademies.org/event/07-08-2020/meeting-3-decadal-survey-of-behavioral-and-social-science-research-on-alzheimers-disease-and-alzheimers-disease-related-dementias-and-workshop-4

There is overwhelming need for nonpharmacological interventions to improve the health and well-being of people living with dementia (PLWD). The National Institute on Aging Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias Clinical Trials (IMPACT) Collaboratory supports clinical trials of such interventions embedded in healthcare systems. The embedded pragmatic clinical trial (ePCT) is ideally suited ...

Embedded pragmatic clinical trials (ePCTs) of nondrug interventions for Alzheimer’s disease and Alzheimer’s disease–related dementias (AD/ADRD) are conducted in real-world clinical settings and designed to generate an evidence base to inform clinical and policy decisions about care for this vulnerable population. The ePCTs exist within a complex ecosystem of relationships between researchers, payors, policymakers, healthcare ...

Outcome measures for embedded pragmatic clinical trials (ePCTs) should reflect the lived experience of people living with dementia (PLWD) and their caregivers, yet patient and caregiver-reported outcomes (PCROs) are rarely available in large clinical and administrative data sources. Although pragmatic methods may lead to use of existing administrative data rather than new data collected directly ...

Using Healthcare Data in Embedded Pragmatic Clinical Trials among People Living with Dementia and Their Caregivers: State of the Art June 26, 2020  Authors: Julie P.W. Bynum, MD, MPH, David A. Dorr, MD, Julie Lima, MPH, Ellen P. McCarthy, PhD, Ellen McCreedy, PhD, Richard Platt, MD, and V.G. Vinod Vydiswaran, PhD Core/Team: Technical Data Core Abstract: Embedded pragmatic clinical ...