The NIA IMPACT Collaboratory plans to publish a Request for Applications (RFA) for Pilot Grants on August 16, 2021 with Letters of Intent due September 17, 2021. IMPACT funds several one-year awards of pilot pragmatic clinical trials (ePCTs) that test non-pharmacological interventions embedded in health care system(s) for people living with Alzheimer’s Disease (AD) and AD-related ...

Asymptomatic and symptomatic infection rates fell dramatically after vaccinations in a large multi-state sample of nursing home residents, reported Wednesday in the New England Journal of Medicine A study of more than 22,000 nursing home residents shows that the COVID-19 mRNA vaccines are highly effective under real-world conditions in reducing infection in this vulnerable population. The ...

The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory has been awarded two COVID-19 Supplements partnering with major retail pharmacies to create a massive monitoring system of the long-term safety and efficacy of COVID-19 vaccination on people with AD/ADRD. The monitoring system was first established in ...

The NIA IMPACT Collaboratory hosted the second annual Steering Committee & Business Planning Meeting on April 6-7, 2021.  The meeting was virtual this year due to the pandemic, and included more than 130 participants. Highlights from the event include remarks from Richard Hodes, MD, the director of National Institutes on Aging, a Mission Moment presented by ...

IMPACT Collaboratory held its first annual Training Workshop and Retreat, “Building Skills to Conduct Embedded Pragmatic Clinical Trials for People Living with Dementia (PLWD) and their Care Partners,” on April 7-8. The training was open to early to mid-career researchers seeking to develop competence in designing and conducting ePCTs of interventions to improve care for ...

Vincent Mor, PhD,  IMPACT Multiple  Principal Investigator and longtime professor of health services, policy and practice at Brown University, was one of two recipients of the Susan Colver Rosenberger Medal of Honor during Brown’s graduation service on May 2nd. Mor was recognized for the “stunning impact” of his service, leadership and research over four decades at ...

The NIA IMPACT Collaboratory plans to publish a Request for Applications (RFA) for Pilot Grants on August 16, 2021 with Letters of Intent due September 17, 2021. IMPACT funds several one-year awards of pilot pragmatic clinical trials (ePCTs) that test non-pharmacological interventions embedded in health care system(s) for people living with Alzheimer’s Disease (AD) and AD-related ...

The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore the inclusion of diverse participants in pragmatic clinical trials. This series will include topics on increasing engagement of diverse participants and building trust, including diverse sites, learning from implementation science to maximize diversity, and ...

Public Attitudes toward Consent When Research Is Integrated into Care—Any “Ought” from All the “Is”? April 11, 2021 Emily Largent, JD, PhD, RN, Associate Core Leader of the IMPACT Ethics and Regulation Core, recently co-authored a journal article in The Hastings Center Report addressing public address towards consent in pragmatic research. The authors recommend prioritizing data about ...

Eric B. Larson, MD, MPH, Core Leader of the IMPACT Health Care Systems Core, recently published a commentary on a new report from the National Academies of Sciences, Engineering, and Medicine. The report, Meeting the Challenges of Caring for Persons Living with Dementia and Their Care Partners and Caregivers, assesses the body of evidence on ...