Multiple IMPACT members participated in the National Institute on Aging (NIA) R13 consensus conference, Pragmatic Trials in Long-Term Care: A Consensus Conference, held virtually on March 10, 2021.  The event was funded by the NIA and led by editors of three leading geriatrics journals:  JAMDA (The Journal of Post-Acute and Long-Term Care Medicine), JAGS (The ...

A large pragmatic trial is the right solution for testing anti-amyloid therapies for Alzheimer’s disease February 6, 2022 NIA IMPACT Collaboratory multiple principal investigator Vince Mor, PhD co-authored a commentary article describing the potential for using pragmatic research designs that promote fairness and equity to conduct research studies on the efficacy of anti-amyloid therapies to treat Alzheimer’s ...

The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is happy to announce a Request for Applications (RFA) for the Pilot Grants Program Cycle 4A. In this cycle, the IMPACT Collaboratory will fund up to five 1-year awards for pilot pragmatic clinical trials (ePCTs) that test ...

A Review Identified Challenges Distinguishing Primary Reports of Randomised Trials for Meta-Research: a Proposal for Improved Reporting January 23, 2022 Meta-research is the discipline of studying research itself. A core investigative tool in meta-research is the use of systematic or scoping reviews to study the characteristics, methods, and reporting of primary research studies. In the context of ...

The NIA IMPACT Collaboratory is now offering two separate funding opportunities: Career Development Award and the Health Care Systems (HCS) Scholars Program.  These opportunities support research and training to increase the nation’s capacity to conduct pragmatic clinical trials (ePCTs) of non-pharmacological interventions within healthcare systems to improve care for people living with Alzheimer’s disease (AD) ...

The IMPACT Collaboratory is happy to announce the recipients of Cycle 3A of the IMPACT Pilot Grant Award Program. Recipients were selected from an impressive group of competitive applications. IMPACT Collaboratory Pilot Grant Award Recipients (RFA 2021) Elizabeth Ciemins, PhD, MPH, MA, American Medical Group Association (AMGA) Implementation of MIND at Home Program in Primary Care for People ...

A qualitative analysis of communication workflows between adult day service centers and primary care providers December 29, 2021 Members of the NIA IMPACT Collaboratory found that Adult Day Care Centers (ADCs) can be resources for important information for primary care providers (PCPs) about people living with dementia (PLWD), but communication barriers and complicated communication workflows frequently prevent ...

We are pleased to announce that the IMPACT Collaboratory plans to publish two Requests for Applications (RFA) on January 10, 2022. Stay tuned for more details. Career Development Award (CDA) Program CDA RFA Cycle 3 $100k per year in direct costs for 2 years Goal: Mentored training grant for early-stage investigators to gain skills needed to conduct ePCTs for dementia ...

Monica Taljaard, PhD, member of the executive committee of the IMPACT Design & Statistics Core, has co-authored a publication describing the prevalence of multiple primary outcomes, changes in primary outcomes and target sample sizes between protocols and final reports, and how issues of multiplicity are addressed in pragmatic trials.

Informed consent in pragmatic trials: results from a survey of trials published 2014–2019 November 15, 2021 IMPACT members recently co-authored an article in the Journal of Medical Ethics, Informed consent in pragmatic trials: results from a survey of trials published 2014–2019, describing reporting of information related to informed consent in reports about pragmatic trials published 2014-2019. Spencer Hey, ...