IMPACT Collaboratory Announces Recipients of Two Funding Mechanisms: Demonstration Projects and Pilot Grants

The NIA IMPACT Collaboratory is pleased to announce the awardees of the Demonstration Projects Program Cycle 2 and the Pilot Grants Program Cycle 3B. Awardees of these opportunities will be supported by IMPACT’s Cores and Teams to conduct embedded pragmatic clinical trials (ePCTs) of non-pharmacological interventions within healthcare systems to improve care for people living with Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD) and their care partners. The IMPACT Collaboratory prioritizes applications that promote health equity and address dementia care for people of all backgrounds. Learn more about IMPACT Collaboratory funding opportunities and general information on the website. Read more about these opportunities and our newest awardees below.

Demonstration Projects Program Cycle 2

The Demonstration Projects Program is a funding mechanism developed to support full-scale, Stage IV effectiveness ePCTs (based on the NIH Stage Model) that test non-pharmacological interventions for people living with AD/ADRD and their care partners embedded within and linked to the needs of a health care system. The goal of Demonstration Projects is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems. The intervention typically includes relatively simple system changes, direct patient outreach, or successfully piloted programs ready for testing at scale.

Cycle 2 recipients are:

  • Ira Hofer, MD, Icahn School of Medicine, and Susana Vacas, MD, PhD, Massachusetts General Hospital, Harvard Medical School
    Mitigation of Postoperative Delirium in High-Risk Patients
  • Lisa Kern, MD, MPH, Weill Cornell Medicine
    Improving How People Living with Dementia are Selected for Care Coordination: A Pragmatic Clinical Trial Embedded in an Accountable Care Organization

Pilot Grant Program Cycle 3B

The Pilot Grant Program funds several one-year pilots for ePCTs that test non-pharmacological interventions embedded in health care system(s) to improve care for people living with AD/ADRD and their care partners. Pilot studies are conducted to generate the preliminary data necessary to design and conduct future full-scale Stage IV effectiveness ePCT (based on the NIH Stage Model) that will be funded through other grant mechanisms (National Institutes of Health or other sources).

Cycle 3B recipients are:

  • Jennifer Carnahan, MD, MPH, MA, Indiana University School of Medicine
    Embedded Clinical Trial of Patient Priorities Care Among People Living with Mild Cognitive Impairment and Dementia
  • Helen Kales, MD, University of California, Davis
    Reducing Inappropriate Medication use for Behavioral and Psychological Symptoms of Dementia and Improving Health Outcomes in People Living with Dementia
  • Donovan Maust, MD, MS, University of Michigan
    A Patient-Facing Tool to Reduce Opioid, Psychotropic Polypharmacy in People Living With Dementia
  • Elizabeth Phelan, MD, MS, University of Washington
    Deprescribing to Reduce Injurious Falls among Older Adults with Dementia (STOP-FALLS-D)