LEAP! Rx: A randomized trial of a pragmatic approach to lifestyle medicine

December 2025 - In Grand Rounds 61, Amber Watts, PhD and Amanda N. Szabo-Reed, PhD discuss “LEAP! Rx: A randomized trial of a pragmatic approach to lifestyle medicine.”

Speakers

Amber Watts, PhD
Associated Professor
University of Kansas
Director, BRANCH LAb

Amanda N. Szabo-Reed, PhD
Research Associate Professor
University of Kansas Medical Center

Learning Objectives

  • Understand why exercise is important for Alzheimer’s disease prevention.
  • Recognize barriers to translating exercise research into clinical practice.
  • Learn how the LEAP! Rx trial was designed and implemented.
  • Compare outcomes and adherence between physician-referred and self-referred participants.
  • Explore strategies for supporting long-term exercise habits in older adults.