The Journal of the American Geriatrics Society (JAGS) has published a special issue (Volume 68, S2) focused solely on the National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory and the activities and progress it has made since the September 2019 announcement. The special issue, published online June ...

LIVE@Home.Path—innovating the clinical pathway for home-dwelling people with dementia and their caregivers: study protocol for a mixed-method, stepped-wedge, randomized controlled trial June 9, 2020 IMPACT Design and Statistics Core Leader Heather Allore, PhD, contributed to a publication describing the rationale, development, feasibility testing and implementation process of the LIVE@Home.Path trial. Abstract Background The global health challenge of dementia is exceptional ...

The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is happy to announce the recipients of its inaugural cycle of the IMPACT Pilot Grant award program. Recipients were selected from an impressive group of competitive applications. IMPACT Pilot Grant Award Recipients (RFA 2019) Brent Forester, MD, MSc, ...

The NIH Health Care Systems Research Collaboratory is launching a special workshop series on its popular Grand Rounds program to explore challenges and opportunities in using electronic health records (EHRs) in pragmatic clinical trials. The series will highlight advances in digital health, new approaches and evolving standards for EHRs, and implications for researchers conducting pragmatic ...

The NIH Health Care Systems Research Collaboratory recently released a summary of a 2019 comprehensive workshop to explore and discuss statistical issues encountered with embedded pragmatic clinical trials (ePCTs). The new Workshop Summary describes panel discussions with the principal investigators and statisticians of NIH Collaboratory Demonstration Projects and the challenges and solutions encountered during the ...

The National Institute on Aging (NIA) IMbedded Pragmatic Alzheimer’s disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory has released two new funding opportunities available for investigators interested in developing embedded pragmatic clinical trials in dementia research. In support of our mission, the IMPACT Collaboratory is requesting applications for the Pilot Grant Award and ...

On April 15 2020, the National Academies’ Committee on Care Interventions for Individuals with Dementia and Their Caregivers hosted a virtual public workshop. This workshop brought together key stakeholders and experts to provide input to the committee on a draft Agency for Healthcare Research and Quality (AHRQ) systematic review that examines existing evidence on care ...

We are pleased to share a new report from the IMPACT Stakeholder Engagement Team, led by Gary Epstein-Lubow, MD and Katie Maslow, MSW, regarding stakeholder research priorities. This report is a compilation of work beginning with input from the NIA IMPACT Collaboratory’s Stakeholder Advisory Committee and then finalized after additional Stakeholder Engagement Team discussion during and following ...

The latest blog post from Keith Goldfeld, DrPH, MS, MPA, member of the executive committee of the IMPACT Collaboratory Design and Statistics Core, discusses how the design effect could provide additional insight into cluster randomized trials in his most recent blog post. The ideas in this blog post were motivated in part by Goldfeld’s work ...

The Tailored Activity Plan (TAP),  a home-based occupational therapy intervention shown to reduce behavioral symptoms in people living with dementia and caregiver burden, was recently included in an article in the Wall Street Journal. The TAP program was developed by Laura Gitlin, PhD, FGSA, FAAN, Dean and distinguished professor at College of Nursing and Health ...