Transforming Dementia Care Through Pragmatic Clinical Trials Embedded in Learning Healthcare Systems
June 26, 2020 Continue reading
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NIA IMPACT Collaboratory Featured in JAGS Special Issue
The Journal of the American Geriatrics Society (JAGS) has published a special issue (Volume 68, S2) focused solely on the National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory and the activities and progress it has made since the September 2019 announcement.
The special issue, published online June 26, includes an introductory article describing the mission and vision of the IMPACT Collaboratory and articles from each of the 10 IMPACT cores and teams describing how they are working to achieve that mission. The introductory article authors are the two IMPACT principal investigators, Susan Mitchell, MD, MPH, senior scientist at Hebrew SeniorLife’s Hinda and Arthur Marcus Institute for Aging Research and professor of medicine at Harvard Medical School and Vincent Mor, PhD, Professor of Health Services, Policy & Practice and the Florence Pirce Grant University Professor, Brown University School of Public Health, as well as the two executive directors, Ellen McCarthy, PhD, MPH, Associate Scientist, Marcus Institute, and Associate Professor of Medicine and Epidemiology, Harvard Medical School, and Jill Harrison, PhD, Assistant Professor of Health Services, Policy and Practice, Brown University School of Public Health.
Mitchell is guest editor for the special issue of JAGS, which includes articles from the IMPACT cores and teams to provide insight into how each is working to improve the quality and effectiveness of ePCTs in PLWD and their care partners. The article titles are:
- Achieving Health Equity in Embedded Pragmatic Trials for People Living with Dementia and Their Family Caregivers
- Building a National Program for Pilot Studies of Embedded Pragmatic Clinical Trials in Dementia Care
- Training the Workforce to Conduct Embedded Pragmatic Clinical Trials to Improve Care for People Living with Dementia and Their Caregivers
- Dissemination and Implementation of Evidence-Based Dementia Care Using Embedded Pragmatic Trials
- Ethical and Regulatory Issues for Embedded Pragmatic Trials Involving People Living with Dementia
- Transforming Dementia Care Through Pragmatic Clinical Trials Embedded in Learning Healthcare Systems
- Using Healthcare Data in Embedded Pragmatic Clinical Trials among People Living with Dementia and Their Caregivers: State of the Art
- Selecting Outcomes to Ensure Pragmatic Trials Are Relevant to People Living with Dementia
- Engaging Stakeholders in the Design and Conduct of Embedded Pragmatic Clinical Trials for Alzheimer’s Disease and Alzheimer’s Disease–Related Dementias
- Statistical Considerations for Embedded Pragmatic Clinical Trials in People Living with Dementia
IMPACT Collaboratory funds two pilot study awards
The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is happy to announce the recipients of its inaugural cycle of the IMPACT Pilot Grant award program. Recipients were selected from an impressive group of competitive applications.
IMPACT Pilot Grant Award Recipients (RFA 2019)
Brent Forester, MD, MSc, Mass General Brigham
Implementation of the Care Ecosystem training model for individuals with dementia in a high risk, integrated care management program
Ula Hwang, MD, MPH, Icahn School of Medicine at Mount Sinai
Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department
About IMPACT Collaboratory
The IMPACT Collaboratory was established in 2019 to meet the urgent public health need to deliver high quality, evidence-based care to people living with dementia (PLWD) and their care partners within the healthcare systems (HCS) that serve them. The IMPACT Collaboratory accomplishes this mission by building the nation’s capacity to conduct embedded pragmatic clinical trials (ePCTs) among people living with dementia and their care partners through building investigator capacity, funding and supporting the design and conduct of ePCTs, and ensuring the research includes culturally-tailored interventions and people from diverse and under-represented backgrounds.
The IMPACT Collaboratory brings together multidisciplinary experts from across the nation organized into 10 Working Cores Groups and Teams. The cores and teams partner with health care system leaders and key stakeholders to support the IMPACT mission. The IMPACT Collaboratory hosts monthly Grand Rounds and podcasts open to everyone to provide insight into conducting ePCTs for PLWD and their care partners. Learn more on our website, Twitter and LinkedIn.
About IMPACT Collaboratory’s Pilot Grant Program
The IMPACT Collaboratory funds several one-year pilot studies annually, which are meant to generate the preliminary data necessary to design and conduct future full-scale, stage 4 effectiveness ePCTs funded through other grant mechanisms. Awards are for single Principal Investigator applications for one year and are non-renewable. The IMPACT Collaboratory encourages applications that address dementia care for people of all backgrounds and promote health equity.
Currently Accepting Applications for 2020 IMPACT Pilot Grant Program
Award applications for the current awards cycle opened April 28, 2020. The application process is a 2-step competitive process. The first step, a mandatory LOI, is due no later than May 29, 2020. Selected investigators will be invited to submit a full application.
In response to the coronavirus disease (COVID-2019) outbreak, in this award cycle, the IMPACT Collaboratory will prioritize applications proposing pilot ePCTs of telemedicine, telehealth, and remote technologies interventions aimed at improving the health care, unmet needs, quality of life and/or health outcomes for people living with AD/ADRD and their care partners. Applications for pilot ePCTs testing other types of non-pharmacological interventions in this population will also be considered.
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