D-CARE: Results of a Pragmatic Intervention Trial and Implications for the GUIDE model

April 16, 2026 – Grand Rounds 65,  David Reuben, MD, and Jeff Williamson, MD, MHS, presented D-CARE: Results of a Pragmatic Intervention Trial and Implications for the GUIDE model.

 

David Reuben, MD

Professor of Medicine
David Geffen School of Medicine
UCLA

Jeff Williamson, MD, MHS 

Professor, Chief of Geriatric Medicine, and Director for the Center for Healthcare Innovation at Wake Forest School of Medicine

Learning Objectives

  • To understand the differences between health system-based and community-based dementia care.
  • To recognize the differences between structured dementia care programs and usual care.
  • To interpret the implication of D-CARE's findings on dementia care and Medicare's GUIDE program.

Identifying and Engaging Care Partners through Electronic Health Records for Pragmatic Research

March 2026 – Grand Rounds 64, IMPACT PCRO Core member Dr. Hillary Lum and guest speakers Drs. Julia Burgdorf and Jenny Portz, and Jody Long present on “Identifying and Engaging Care Partners through Electronic Health Records for Pragmatic Research.”

Hillary Lum, MD, PhD

IMPACT Patient/Caregiver Relevant Outcomes Core

Professor of Medicine, Division
of Geriatric Medicine,
Department of Medicine,
University of Colorado Anschutz

Jenny Portz, PhD, MSW

Associate Professor, General Internal Medicine, University of Colorado Anschutz

Julia Burgdorf, PhD

Research Scientist, Center for Home Care Policy & Research at VNS Health

Jody Long, MSN, MBA, RN, CEN

Director of Clinical Affairs, PointClickCare

Learning Objectives

  • Communicate the need and promise for improvement of dementia care with embedded pragmatic trials within dynamic health care settings.
  • Review what we have found to be key components of ePCT trial design and conduct for ensuring that study results are implementable.
  • Provide learnings of two ePCT trialists from The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care (D-CARE)

 

IMPACT Awardee Earns Pilot Grant to Study Dementia Care Quality

IMPACT Career Development Awardee Erica Frechman, PhD, AGPCNP-BC was awarded a Pilot Grant from the National Dementia Workforce Study for her study, Advance Practice Providers and Dementia Care: Role of Training, Preparedness, and Practice Setting for Patient Outcomes. IMPACT executive committee member Jennifer Gabbard, MD is a co-investigator for this study.

Frechman’s study will leverage the Community Clinician survey and CMS claims data to examine APPs and how their dementia-specific training, preparedness, and practice settings are associated with meaningful variation in care quality and outcomes for people living with dementia.

Learn more about Pilot Grant awardees here.

Yale School of Medicine Seeks Postdoctoral Associate in Gerontologic Biostatistics

Yale School of Medicine is hiring a Postdoctoral Associate in Gerontologic Biostatistics for a 2.5-year full-time position. This role focuses on methodological development in pragmatic dyadic study design within embedded pragmatic clinical trials (ePCTs). Mentorship will be provided by Drs. Joan Monin and Heather Allore (Yale School of Public Health) and Dr. Thomas Travison (Harvard Medical School).

Learn more about the position and how to apply here.

Notice of Intent (NOI) to Publish Two New Funding Opportunities Later in October

The IMPACT Collaboratory is pleased to announce plans to publish Requests for Applications (RFA) for Pilot ePCT Grants and Demonstration Projects of non-pharmacologic interventions for people living with dementia (PLWD) and their care partners in mid-October 2025. Letters of Intent for both opportunities are due in November.

Pilot Grants Program
IMPACT will fund up to three 18-month awards for up to $300,000 pilot embedded pragmatic trials (ePCTs) that are designed to demonstrate the feasibility and inform the design of a future full-scale ePCT to evaluate non-pharmacological interventions embedded in health care system(s) for people living with dementia (PLWD) and their care partners. Learn more about previous awardees here.

RFA Release Date: October 14, 2025

LOI Due Date: November 6, 2025

 

Demonstration Projects Program

IMPACT will fund up to two 24-month awards of up to $800,000 for Demonstration Projects designed as full-scale, Stage IV effectiveness ePCTs (based on the NIH Stage Model) that evaluate the effectiveness of a non-pharmacological intervention in a large-scale ePCT for people living with dementia (PLWD) and their care partners. Learn more about previous awardees here.

Learn more about previous awardees here.

RFA Release Date: October 20, 2025

LOI Due Date: November 13. 2025

 

Stay tuned for updates regarding the release of these RFAs. Visit IMPACTcollaboratory.org to learn more about our Grants and Training Programs.

Questions? Email us at IMPACTcollaboratory@hsl.harvard.edu.

Kern picture, Grand Rounds Feb 2025

Improving How PLWD are Selected for Care Coordination: ePCT in an ACO

February 2025 - Lisa Kern, MD, MPH, discusses "IMPACT Demonstration Project | Improving How People Living with Dementia are Selected for Care Coordination: Pragmatic Clinical Trial Embedded in an Accountable Care Organization"

Speakers

Lisa Kern, MD, MPH
Associate Professor
Weill Cornell Medicine

Learning Objectives

  • Understand the concept of healthcare fragmentation in general
  • Understand the relevance of healthcare fragmentation specifically for people
    living with dementia
  • Reflect on the results of a pragmatic clinical trial that included people living
    with dementia who had highly fragmented care

 

Sullivan_June 2025 Grand Rounds card

Meta Lessons Learned from Pilot and Demonstration Projects Implementation 

June 2025 –  In Grand Rounds 57, Jennifer Sullivan, PhD, describes lessons learned from IMPACT Pilot and Demonstration Projects implementation data.

Speakers

Jennifer Sullivan, PhDJennifer Sullivan, PhD
Associate Professor, Brown University School of Public Health
Department of Health Service, Policy and Practice

Associate Director & Investigator
THRIVE COIN
VA Providence Healthcare System

Learning Objectives

  • Describe factors enabling and/or hindering pilot and demonstration project implementation
  • Understand which implementation strategies were being used by pilot and demonstration grants
  • Gain knowledge about how implementation progress was made by programs over the funding timelines

 

RWD Scholars headshots

Bridging Research and Practice: An Update from Real World Data Scholars

May 2025 – In Grand Rounds 56, the 2023 Real World Data Scholars presented on their research projects using the Long-Term Care (LTC) Data Cooperative dataset.

Webinar Slides

Headshot of Jinying Chen, PhD from the shoulders upJinying Chen, PhD

Boston University Chobanian & Avedisian School of Medicine

Validating Medication Orders by Leveraging Natural Language Processing

Headshot of Kenneth Lam, MD, MAS from the shoulders up, smiling and wearing a suit.

Kenneth Lam, MD, MAS  

University of Colorado
School of Medicine

Validation of Functional Measures in LTC EHR Data

Headshot of Lindsay White from the shoulders up.Lindsay White, PhD

University of Pennsylvania Perelman School of Medicine

Determination of Cognitive Status in NH Residents: The Utility of EHR Data

Headshot of Yongkang Zhang, Phd, MS from the shoulders up.

Yongkang Zhang, PhD, MS 

Weill Cornell Medical College

Evaluating LTC Data Cooperative EHRs to Study T2D among Nursing Home Residents

Dr. Possin Grand Rounds card

Augmenting Nurse Support and EHR Integration for the Pragmatic Trial of the TabCAT Brain Health Assessment

April 2025 – In Grand Rounds 55, Katherine Possin, PhD, discusses "Augmenting Nurse Support and Electronic Health Record (EHR) Integration for the Pragmatic Trial of the TabCAT Brain Health Assessment (TabCAT-BHA)." TabCAT-BHA is a software platform owned by UCSF to provide diagnosis in MCI and dementia.

Speakers

Katherine Possin, PhD

Katherine Possin, PhD
John Douglas French Alzheimer’s Foundation Endowed Professorship
Professor in Residence
Department of Neurology
UCSF Memory and Aging Center

Learning Objectives

  • Learn about the DetectCID Consotrium and TabCAT-Brain Health Assessment
  • Understand implementation of TabCAT-BHA as part of a diagnostic care pathway at UCSF primary care (DetectCID-1) and Kaiser Permanente Southern California primary care (DetectCID-2)
  • Understand scaling TabCAT-BHA & Brain Health Consultation