Grand Rounds and Podcasts
The IMPACT Collaboratory works to build the nation’s capacity to conduct pragmatic clinical trials (ePCTs) of interventions embedded within health care systems for people living with dementia and their care partners. We host free webinars on the 3rd Thursday of each month at 12 noon ET addressing these issues. Registration is not required. To receive updates and reminders about Grand Rounds, join our mailing list.
After each Grand Round presentation, a video recording and webinar slides will be posted on this page. Some sessions also feature a companion podcast.
- D-CARE: Results of a Pragmatic Intervention Trial and Implications for the GUIDE model

- Identifying and Engaging Care Partners through Electronic Health Records for Pragmatic Research

- Learn as You Go (LAGO) Design

- Home Time as a Patient-Centered Outcome in Pragmatic Trials: Promise, Pitfalls, and the Path Forward

- LEAP! Rx: A randomized trial of a pragmatic approach to lifestyle medicine

- Using pragmatic trials to address prescription safety in older patients with diabetes

- Building the NEXT STEPs Network

- Improving How PLWD are Selected for Care Coordination: ePCT in an ACO

- Meta Lessons Learned from Pilot and Demonstration Projects Implementation

- Bridging Research and Practice: An Update from Real World Data Scholars

- Augmenting Nurse Support and EHR Integration for the Pragmatic Trial of the TabCAT Brain Health Assessment

- 5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care: Pragmatic Clinical Trial

- Improving Advance Care Planning for Seriously Ill Primary Care Patients: UC Health Care Planning Study

- COVID Vaccination among Medicare Beneficiaries: Findings from an IMPACT Supplement

- Using Pilot Studies to Inform ePCTs in Hispanic/Latino People Living with Dementia and their Care Partners

- Evidence for Reducing Infections, Hospitalizations, and Antibiotic Resistant Pathogens in Nursing Homes through Universal Nasal Decolonization & Bathing with Chlorhexidine

- Current and future use of RE-AIM and its PRISM expansion, and their application in pragmatic trials

- The GUIDE Model: A CMS payment model test to support people living with dementia and their family caregivers

- The WHELD Programme

- Diagnosed Dementia in Medicare: Benchmarking for Study Planning and Equity

- Cultural adaptation of ADRD clinical trials for Latino participants

- Strategies to Implement ePCTs in Home and Community-Based Settings – Issues and Successes in Assisted Living and Adult Day Centers

- The Clinical Implementation of Alzheimer’s Disease Biomarkers

- Outcomes truncated by death in randomized trials

- Electronic Nudges and Pragmatic Trials to Improve Hospital Palliative Care Delivery

- Decision Architecture Randomization Trials: Extremely Low-Cost Trials with Preservation of Clinician and Patient Choice

- Results and Lessons Learned from the HAS-QOL ePCT

- eRADAR: An embedded, pragmatic trial using electronic health record data for targeted dementia screening

- More than a Meal: Results from a Pilot Pragmatic Clinical Trial Evaluating Two Models of Home-Delivered Meals for Older Adults Living with Dementia

- Causal Inference in Pragmatic Trials

- Methods for Designing Cluster Randomized Trials to Detect Treatment Effect Heterogeneity

- Adaptation of behavioral interventions and use of FRAME

- The REGAIN Trial Experience

- Addressing vulnerability in cluster randomized trials involving people living with dementia in nursing homes

- Developing standards and quality metrics for clinical phenotyping using EHR data in pragmatic clinical trials

- CHATO design, pilot testing and update on current implementation and results

- Update on IMPACT Funded Pilot Studies

- Deprescribing Education vs Usual Care for Patients with Cognitive Impairment and Primary Care Clinicians: The OPTIMIZE Pragmatic Cluster Randomized Trial

- Embedding Health Equity in a Cluster Randomized Trial of an Advance Care Planning Intervention

- CMO Panel: How to Achieve Health Systems Change

- Lessons From the First Decade of the NIH Pragmatic Trials Collaboratory

- Healthcare-Generated Data to Identify People Living with Dementia for Embedded Pragmatic Trials

- Partnering with People Living with Dementia and Care Partners in Embedded Pragmatic Clinical Trials

- Challenges conducting pragmatic trials of interventions for care partners of people living with dementia

- Dyadic designs, their foundation on theory and analytic methods

- Challenges Implementing Innovative Programs in Long Term Care: Examples from Pragmatic Trials

- Promises and Pitfalls of Existing Data in Nursing Homes

- Pilot and feasibility studies for pragmatic cluster randomised trials

- Inclusion, diversity, and equity in pragmatic clinical trials

- Update on Two IMPACT Funded Pilot Studies

- Ethical challenges with pragmatic RCTs: General issues and special considerations in dementia

- Implementation in ongoing ADRD ePCTS in different health care settings using real examples

- Improving Serious Illness Care Through Large Pragmatic Trials

- Implementation Outcomes: Their Role in Treatment Success

- The AHRQ and Lancet Reports on Dementia Interventions: Interpretation and Implications for Embedded Pragmatic Trials

- Not all approaches to data are equal: Data-related challenges for pragmatic trials involving PLWD

- Breaking the Cycle: Health Care Systems Interactions for Impactful Results

- Finding Pragmatic and Relevant Outcomes for AD/ADRD ePCTs

- Covid-19 Among Older Persons in Health Care Systems: Pragmatic Responses to the Crisis

- Stakeholder Engagement in ePCTs for People Living with Dementia

- COVID-19 in Nursing Homes: Pragmatic Research Responses to the Crisis

- Health equity as foundational to the design of pragmatic trials

- Modifications and Waivers of Informed Consent in Pragmatic Clinical Trials

- Using a Pilot to Test and Refine Your Measurement Strategy

- Stepped Wedge Cluster Randomized Trials: What, How, And When?

- Are you ready for a pragmatic trial? The RAPT model and implementation considerations

Upcoming Grand Rounds
Grand Rounds is on the 3rd Thursday of each month at 12pm ET, September – June
Grand Rounds: Stephanie Morain, PhD, MPH
May 21 @ 12:00 pm - 1:00 pm