Design and Statistics Core
Core Activities
The Design and Statistics Core focuses on biostatistical methods for the design, conduct, and analysis of health system-embedded pragmatic clinical trials (ePCTs) among people living with dementia (PLWD) and care partners.
Core members develop and disseminate novel biostatistical approaches for the design and conduct of ePCTs; provide guidance to investigators on design, power and sample size, analytic methods and reproducibility. They train the next generation of biostatisticians and collaborate with other Cores on the development of methods and tools supporting ePCT design.
Key Resources
News
- Design and Statistics core members review recent publications for adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials
- IMPACT Collaboratory announces two new resources to aid in the design of ePCTs
- Recent IMPACT team article describes formal methods for sample size and power analyses for testing subgroup-specific treatment effects in parallel-arm CRTs
- Authors comment on antibiotic use considerations for patients receiving end-of-life care
- Article explores patient and public involvement in pragmatic trials
Leadership
Heather Allore, PhD Core Leader |
Thomas Travison, PhD Associate Core Leader |