Regulation & Ethics Core

Hey, Spencer – PhD
Credentials: PhD
Role:

Executive Committee, Regulation & Ethics Core

Primary title: Faculty and Co-Director of Research Ethics
Primary Institution: Harvard Center for Bioethics
Complete Titles:

Faculty and Co-Director of Research Ethics, Harvard Center for Bioethics

Bio: Spencer Hey, PhD, is a faculty member and Co-Director of Research Ethics at the Harvard Center for Bioethics. He received his PhD in philosophy from the University of Western Ontario and previously held a postdoctoral fellowship in the Biomedical Ethics Unit at McGill University and a visiting scholarship at Oxford University. Dr. Hey’s research interests lie at the intersection of biomedical ethics and philosophy of science—with a focus on clinical trials and the ethical challenges that arise across the drug research and development enterprise. His published work has appeared in scientific, medical, bioethics, and philosophical venues, including Science Magazine, JAMA Internal Medicine, Neurology, The BMJ, PLoS Medicine, Journal of Medical Ethics, Hastings Center Report, Perspectives in Biology and Medicine, and Philosophy of Science.
Core/Team Associations:
Hoffman, Allison – JD
Credentials: JD
Role:

Executive Committee, Regulation & Ethics Core

Primary title: Professor of Law
Primary Institution: University of Pennsylvania Law School
Complete Titles:

Professor of Law, University of Pennsylvania Law School
Senior Fellow, Leonard Davis Institute of Health Economics

Bio: Allison K. Hoffman, JD, an expert on health care law and policy, is a professor of law at University of Pennsylvania Law School and a senior fellow at the Leonard Davis Institute of Health Economics. She was a visiting professor of Law at Yale Law School in Spring 2019 and on the faculty of the UCLA School of Law from 2010-2017. Professor Hoffman’s work examines some of the most important legal and social issues of our time, including health insurance regulation, the Affordable Care Act, Medicare and retiree healthcare expenses, and Medicaid and long-term care. Her research aims to bring greater descriptive and analytical clarity to the purposes of health regulation and how it both reflects and shapes our views on distributing risk. She is co-editor of the Oxford Handbook of U.S. Health Law (2017), the most comprehensive review of US health law in the post-ACA era.
Core/Team Associations:
Joffe, Steven – MD, MPH
Credentials: MD, MPH
Role:

Executive Committee, Regulation & Ethics Core

Primary title: Founders Professor of Medical Ethics & Health Policy
Primary Institution: University of Pennsylvania Perelman School of Medicine
Complete Titles:

Founders Professor of Medical Ethics & Health Policy, University of Pennsylvania Perelman School of Medicine
Professor of Pediatrics, Children’s Hospital of Philadelphia
Senior Fellow, Leonard Davis Institute of Health Economics

Bio: Steven Joffe, MD, MPH, is the founders professor of medical ethics and health policy at the University of Pennsylvania Perelman School of Medicine. He serves as Chief of the Division of Medical Ethics and directs its postdoctoral fellowships in biomedical ethics. He is also professor of pediatrics at the Children’s Hospital of Philadelphia (CHOP). He attended Harvard College, received his medical degree from the University of California at San Francisco (UCSF), and received his public health degree from UC Berkeley. Dr. Joffe trained in pediatrics at UCSF and undertook fellowship training in pediatric hematology/oncology at the Dana-Farber Cancer Institute and Boston Children’s Hospital. His research focuses on ethical and regulatory challenges in biomedical research and in learning healthcare systems and on the ethical implications of genomics in research and care.
Core/Team Associations:
Karlawish, Jason – MD
Credentials: MD
Role:

Core Leader, Regulation & Ethics Core

Primary title: Professor of Medicine, Medical Ethics and Health Policy, and Neurology
Primary Institution: University of Pennsylvania
Complete Titles:

Professor of Medicine, Medical Ethics and Health Policy, and Neurology
Co-Director, Penn Memory Center, University of Pennsylvania

Bio: Jason Karlawish, MD is is a professor of medicine, medical ethics and health policy, and neurology at Penn and cares for patients at the Penn Memory Center (www.pennmemorycenter.org), which he co-directs. His research focuses on issues at the intersections of bioethics, aging and the neurosciences. He leads the Penn Program for Precision Medicine for the Brain (P3MB). P3MB developed standards for Alzheimer’s disease biomarker disclosure and investigates the clinical impacts of this knowledge on persons and their families. He has investigated the psychological and ethical implications of biomarker-based Alzheimer’s disease diagnostics and treatments, informed consent, quality of life, research and treatment decision making, stigma and voting by persons with cognitive impairment and residents of long term care facilities.
Core/Team Associations:
Largent, Emily – PhD, JD, RN
Credentials: PhD, JD, RN
Role:

Associate Core Leader, Regulation & Ethics Core

Primary title: Emanuel & Robert Hart Assistant Professor of Medical Ethics and Health Policy
Primary Institution: University of Pennsylvania Perelman School of Medicine
Complete Titles:

Emanuel & Robert Hart Assistant Professor of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine

Bio: Emily Largent, JD, PhD, RN, is an assistant professor in the Department of Medical Ethics and Health Policy and a senior fellow at the Leonard Davis Institute of Health Economics at the University of Pennsylvania. Dr. Largent’s current research focuses on ethical and regulatory aspects of human subjects research, with a particular focus on Alzheimer’s disease research. In 2019, Dr. Largent received a K01 career development award from the National Institute on Aging to understand the research-related role of and effects of biomarker disclosure on study partners in preclinical Alzheimer’s disease research.
Core/Team Associations:
Lima, Julie – PhD
Credentials: PhD
Role:

Team Leader, IRB & Regulation Team
Team Leader, Data Sharing & Standards Team
Executive Committee, Technical & Data Core (TDC)
Executive Committee, Regulation & Ethics Core

Primary title: Assistant Professor, Health Services, Policy & Practice
Primary Institution: Brown University School of Public Health
Complete Titles:

Assistant Professor, Health Services, Policy & Practice, Brown University School of Public Health

Bio: Julie Lima, MPH, PhD, is assistant professor of health services, policy & practice in the School of Public Health at Brown University. She has been with Brown’s Center for Gerontology and Health Care Research for more than 15 years and is the Center’s expert on data compliance and human subjects research regulatory matters. She maintains the Center’s Handbook of Computing and Research, developed its resource sharing procedures in compliance with NIH policies, and trains faculty and research staff on best practices for acquiring and working with sensitive data. She is also a member of Brown University’s Human Research Advisory Group (BhRAG). As a health services researcher, Dr. Lima has hands-on experience working with both survey and administrative data and has collaborated with national leaders in the areas of unmet need for care for people living with functional limitations in the community; quality of care at the end of life; culture change practices in the nursing homes; and post-acute care among Medicare beneficiaries. She received her Masters of Public Health from Boston University and her doctorate from Brown University.
London, Alex John – PhD
Credentials: PhD
Role:

Executive Committee, Regulation & Ethics Core

Primary title: Clara L. West Professor of Ethics and Philosophy; Director of the Center for Ethics and Policy
Primary Institution: Carnegie Mellon University
Complete Titles:

Clara L. West Professor of Ethics and Philosophy
Director of the Center for Ethics and Policy, Carnegie Mellon University

Bio: Alex John London, PhD is the Clara L. West professor of ethics and philosophy and Director of the Center for Ethics and Policy at Carnegie Mellon University. An elected fellow of the Hastings Center, Professor London’s work focuses on ethical and policy issues surrounding the development and deployment of novel technologies in medicine, biotechnology and artificial intelligence, on methodological issues in theoretical and practical ethics, and on cross-national issues of justice and fairness. His papers have appeared in Mind, The Philosopher’s Imprint, Science, JAMA, The Lancet, The BMJ, PLoS Medicine, Statistics In Medicine, The Hastings Center Report, and numerous other journals and collections. He is also co-editor of Ethical Issues in Modern Medicine, one of the most widely used textbooks in medical ethics.
Core/Team Associations: