December 26, 2022
Resource Type
Niznik and co-authors examine deprescribing medications for those with dementia near the end of life
The REGAIN Trial Experience
December 2022 – In Grand Rounds 32, Drs. Mark Neuman and Justin Clapp share results from the REGAIN trial on enrolling and retaining people living with dementia in pragmatic trials involving spinal vs. general anesthesia for hip fracture surgery.
Speakers
Mark Neuman, MD, MSc
Horatio C. Wood Associate Professor of
Anesthesiology & Critical Care
University of Pennsylvania
Perelman School of Medicine
Webinar Recording
No Grand Rounds recording, but check out the podcast!
Justin Clapp, PhD, MPH
Assistant Professor
Anesthesiology & Critical Care
Medical Ethics & Health Policy
University of Pennsylvania
Perelman School of Medicine
Podcast
Podcast Transcript: Download the transcript here.
Addressing vulnerability in cluster randomized trials involving people living with dementia in nursing homes
November 2022 – In Grand Rounds 31, Dr. Weijer shares six different vulnerabilities, and key methods of protection to address them, in cluster randomized trials for people living with dementia in long-term care home settings.
Speaker
Charles Weijer, MD, PhD
Professor
Western University
Podcast
Podcast Transcript: Download the transcript here.
Developing standards and quality metrics for clinical phenotyping using EHR data in pragmatic clinical trials
October 2022 – In Grand Rounds 30, Dr. Richesson describes the use of electronic health records (EHR) to develop standards and quality metrics for computable phenotyping in pragmatic clinical trials.
Speaker
Rachel Richesson, PhD, MPH, FACMI
Professor
Informatics & Learning Health Sciences
University of Michigan School of Medicine
Learning Objectives
- Define computable phenotyping and discuss its relevance to pragmatic clinical trials.
- Discuss approaches to find existing phenotypes and to assess their quality and appropriateness for certain uses.
- Discuss the importance of reporting phenotype definition features and data quality assessment for pragmatic research.