The REGAIN Trial Experience

December 2022 – In Grand Rounds 32, Drs. Mark Neuman and Justin Clapp share results from the REGAIN trial on enrolling and retaining people living with dementia in pragmatic trials involving spinal vs. general anesthesia for hip fracture surgery.

 

Speakers

Mark Neuman, MD, MSc

Mark Neuman, MD, MSc

Horatio C. Wood Associate Professor of
Anesthesiology & Critical Care

University of Pennsylvania
Perelman School of Medicine

Webinar Recording

No Grand Rounds recording, but check out the podcast!

 

 

Justin Clapp, PhD, MPHJustin Clapp, PhD, MPH

Assistant Professor
Anesthesiology & Critical Care
Medical Ethics & Health Policy

University of Pennsylvania
Perelman School of Medicine

Allore joins JAMAevidence podcast to discuss latent class analysis to identify hidden clinical phenotypes

Heather Allore, PhD, Core Leader for the IMPACT Design and Statistics Core, recently appeared on the JAMAevidence podcast to discuss latent class analysis to identify hidden clinical phenotypes. A latent variable is an unobserved variable that investigators don’t have a construct or measure for, but believe it exists and could impact outcomes. Dr. Allore uses frailty as an example of latent variables in the discussion.

The podcast was hosted by JAMA Statistical Editor Roger Lewis, MD, PHD and is a supplement to the JAMA Guide to Statistics and Methods.

Listen to the podcast at this link.

GeriPal Podcast: COVID Vaccine Hesitancy in Frontline Nursing Home Staff

In this podcast, Geripal discusses vaccine hesitancy with Sarah Berry, MD, MPH, Kimberly Johnson, MS, and David Gifford, MD, MPH, and the lessons learned from the “town hall” intervention they did in their recent study published in the Journal of the American Geriatrics Society. Discussion was around the devastating impact of COVID on nursing homes and the effects and update rates of vaccine among patients and staff in nursing home.

NIH Pragmatic Trials Collaboratory and Living Textbook

The NIH Pragmatic Trials Collaboratory aims to improve the way clinical trials are conducted by creating a new infrastructure for collaborative research with healthcare systems, ultimately ensuring that healthcare providers and patients can make decisions based on the best available clinical evidence. The Collaboratory supports the design and rapid execution of pragmatic clinical trial Demonstration Projects to address questions of major public health importance and engage healthcare delivery systems in research partnerships. The Collaboratory also provides training resources on how to design, conduct, and disseminate embedded pragmatic clinical trials (ePCTs).