IMPACT April 2024 Grand Rounds with Professor Clive Ballard from the University of Exeter

The WHELD Programme

April 2024 – In Grand Rounds 46, Dr. Ballard speaks on the WHELD programme  – an evidence-based program developed to coach and support care home staff to deliver better person-centered care and increase opportunities for social interactions with personalized activities for residents living with dementia.

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Speaker

Clive Ballard, MD, MPHClive Ballard, MD, MPH

Professor of Age-Related Diseases

University of Exeter

Learning Objectives

  • Understanding some of the challenges for nursing homes and people with dementia living in these settings
  • Understanding the impacts of psychotropic medications in nursing home residents with dementia
  • Understanding the best evidence regarding interventions to improve outcomes for nursing home residents with dementia

 

Podcast

Coming Soon!

Graphic with headshot of Dr. Julie Bynum from the shoulders up, next to the words "Grand Rounds & Podcast March 2024"

Diagnosed Dementia in Medicare: Benchmarking for Study Planning and Equity

March 2024 – In Grand Rounds 45, Dr. Bynum shares the pros and cons of using healthcare-generated data, such as Medicare Fee-for-Service and Medicare Advantage, to identify people living with Alzheimer's disease and related dementias (ADRD), as well as the use of population benchmarks in study planning and integrating health equity.

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Speaker

Dr. Julie BynumJulie Bynum, MD, MPH

Margaret Terpenning Collegiate Professor of Internal Medicine

Division of Geriatric & Palliative Medicine

University of Michigan

Learning Objectives

  • Identify strengths & challenges when using Medicare data for participant identification
  • Understand characteristics of diagnosed dementia cases across place
  • Consider value of using population benchmarks for planning and equity

 

February 2024 Grand Rounds: Cultural adaptations of ADRD clinical trials for Latino Participants

Cultural adaptation of ADRD clinical trials for Latino participants

February 2024 – In Grand Rounds 44, Drs. Hanson, Lum, Ramirez Gomez, and Fischer discuss barriers to inclusivity in ADRD clinical trials, disparities in caregiving of PLWD, the importance of integrating cultural adaptations and lessons learned from the ADRD-PC trial.

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Stacy Fischer, MD

Stacy Fischer, MD

Professor

University of Colorado Anschutz Medical Campus

 

Hillary Lum, MD, PhD

Hillary Lum, MD, PhD

Associate Professor

University of Colorado Anschutz Medical Campus

 

Laura Hanson, MD, MPHLaura Hanson, MD, MPH

Professor

University of North Carolina School of Medicine

 

Liliana Ramirez Gomez. MDLiliana Ramirez Gomez, MD

Clinical Director

Massachusetts General Hospital

Learning Objectives

  • Review the barriers to ADRD research for diverse populations
  • Learn best practices for engaging Latino ADRD caregiver advisors in research
  • Understand the process of cultural adaptation of ADRD research protocols

 

Results and Lessons Learned from the HAS-QOL ePCT

June 2023 – In Grand Rounds 38, Dr. Ab Brody dives into the results and lessons learned from the Hospice Advanced Dementia Symptom Management and Quality of Life (HAS-QOL) ePCT, a 25-site trial exploring a quality improvement program tailored to improve care for PLWD and their care partners receiving hospice across care settings.

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Speaker

 

Ab Brody, PhD, RN, FAAN

Founder, Aliviado Health

Pilot Studies Core Leader, NIA IMPACT Collaboratory

Mathy Mezey Professor, NYU Rory Meyers College of Nursing
Associate Director, Hartford Institute for Geriatric Nursing

Learning Objectives

  • Understand the current gaps and challenges in providing effective care to people living with dementia and their care partners in hospice.
  • Describe the process of preparing a full-scale ePCT.
  • Summarize challenges and effective solutions, including human support and technology-based strategies, to sustain interdisciplinary dementia care workforce training in hospice settings amid COVID-19 in a 25-site ePCT.

 

eRADAR: An embedded, pragmatic trial using electronic health record data for targeted dementia screening

May 2023 – In Grand Rounds 37, Drs. Barnes and Dublin discuss the use of eRADAR - electronic health record (EHR) Risk of Alzheimer's and Dementia Assessment Rule - for targeted dementia screening in higher-risk older adults.

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Speakers

 

Deborah Barnes, PhD 

Professor
Psychiatry and Behavioral Sciences
Epidemiology & Biostatistics

University of California, San Francisco

 


Sascha Dublin, MD, PhD

Senior Investigator

Kaiser Permanente Washington Health
Research Institute

Learning Objectives

  • Describe eRADAR's accuracy for identifying older patients at risk of undiagnosed dementia.
  • Describe patient acceptance of targeted screening for dementia using eRADAR.
  • Describe preliminary outcomes of brain health assessment visits.

More than a Meal: Results from a Pilot Pragmatic Clinical Trial Evaluating Two Models of Home-Delivered Meals for Older Adults Living with Dementia

April 2023 – In Grand Rounds 36, Dr. Kali S. Thomas shares findings from a pilot pragmatic clinical trial that evaluated the impact of two models of home-delivered meals for older adults living with dementia.

Speaker

Kali S. Thomas, PhD

Associate Professor
Health Services, Policy & Practice

Brown University

Learning Objectives

  • Understand the steps taken to design a pilot pragmatic randomized control trial comparing two types of home-delivered meals among older adults living with dementia.
  • Describe the feasibility of conducting this study, including recruitment, retention, and assessment procedures.
  • Summarize the process for linking data to examine trends in treatment effects.

 

Causal Inference in Pragmatic Trials

March 2023 – In Grand Rounds 35, Dr. Eleanor "Ellie" Murray explores causal inference in randomized pragmatic trials highlighting topics such as immortal time bias, per-protocol effects, and how to use the SMARTER acronym when thinking about causal research questions.

Speaker

Eleanor Murray, PhD

Assistant Professor
Epidemiology

Boston University School of Public Health
@EpiEllie

Learning Objectives

  • Discuss the properties of a good causal research question.
  • Identify two key sources of potential bias common in pragmatic trials.
  • Recognize pragmatic trial scenarios requiring sophisticated causal inference statistical methods.

 

Methods for Designing Cluster Randomized Trials to Detect Treatment Effect Heterogeneity

February 2023 – In Grand Rounds 34, IMPACT Design and Statistics Executive Committee Member, Dr. Fan Li, sheds light on several methods for designing cluster randomized trials (CRTs) to detect the variability of treatment effects for individuals within a population, also known as heterogeneity of treatment effect (HTE).

Speaker


Fan Li, PhD

Assistant Professor
Department of Biostatistics

Yale School of Public Health

Learning Objectives

  • Understand the sample size requirements for testing treatment effect heterogeneity in cluster randomized trials.
  • Be aware of tools for designing cluster randomized trials.
  • A call for involving statisticians at the outset to design cluster randomized trials.

 

Adaptation of behavioral interventions and use of FRAME

January 2023 – In Grand Rounds 33, Dr. Wiltsey Stirman dives into the adaptations of behavioral interventions and describes how the FRAME process can be used to document those adaptations and modifications.

Speaker

Shannon Wiltsey Stirman, PhD

Associate Professor
Psychiatry and Behavioral Sciences

Stanford University

               Download webinar slides.

Learning Objectives

  • Discuss factors that should be considered when adapting behavioral interventions.
  • Describe how the FRAME can be used to document adaptations.
  • Provide examples of study designs to investigate the impact of adaptations.