Author: Mia

The REGAIN Trial Experience

Posted on by Mia

December 2022 – In Grand Rounds 32, Drs. Mark Neuman and Justin Clapp share results from the REGAIN trial on enrolling and retaining people living with dementia in pragmatic trials involving spinal vs. general anesthesia for hip fracture surgery.

 

 

Speakers

Mark Neuman, MD, MSc

Horatio C. Wood Associate Professor of
Anesthesiology & Critical Care

University of Pennsylvania
Perelman School of Medicine

Webinar Recording

Coming Soon!

 

 

 

 

Justin Clapp, PhD, MPH

Assistant Professor
Anesthesiology & Critical Care
Medical Ethics & Health Policy

University of Pennsylvania
Perelman School of Medicine

Podcast


Podcast Transcript: Download the transcript here.

IMPACT hosts special webinar introducing the Long-Term Care Data Cooperative

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December 2022 - The IMPACT Collaboratory hosted a special webinar event December 7, featuring leaders from the Long-Term Care (LTC) Data Cooperative who provided an introduction and overview to this powerful new resource. IMPACT’s Vince Mor, PhD, David Dore, PharmD, PhD, from Exponent, and David Gifford, MD, MPH from the American Health Care Association (AHCA) shared insightful information with participants about the Data Cooperative, its membership, how to join, and options for data access.

Download webinar slides.                                  Download the transcript.

The LTC Data Cooperative will:

  • Assist providers with health care operations, including care coordination, risk stratification and quality performance reporting.
  • Support public health monitoring for medical conditions and infections, including COVID-19.
  • Enable observational studies of the LTC population, ranging from comparative treatment effectiveness studies, to epidemiological studies of risk to pharmaco-epidemiological studies.
  • Facilitate provider and patient recruitment into clinical research studies, including stage 3 and 4 embedded pragmatic clinical trials.

Vince Mor, PhD
Brown University

 

David Gifford, MD, MPH
American Health Care Association

 

David Dore, PharmD, PhD
Exponent, Inc.

Addressing vulnerability in cluster randomized trials involving people living with dementia in nursing homes

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November 2022 – In Grand Rounds 31, Dr. Weijer shares six different vulnerabilities, and key methods of protection to address them, in cluster randomized trials for people living with dementia in long-term care home settings.

Speaker

Charles Weijer, MD, PhD

Professor

Western University

                      Download Webinar Slides

Podcast


Podcast Transcript: Download the transcript here.

Developing standards and quality metrics for clinical phenotyping using EHR data in pragmatic clinical trials

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October 2022 – In Grand Rounds 30, Dr. Richesson describes the use of electronic health records (EHR) to develop standards and quality metrics for computable phenotyping in pragmatic clinical trials.

Speaker

Rachel Richesson

Rachel Richesson, PhD, MPH, FACMI

Professor
Informatics & Learning Health Sciences

University of Michigan School of Medicine

                       Download Webinar Slides

Learning Objectives

  • Define computable phenotyping and discuss its relevance to pragmatic clinical trials.
  • Discuss approaches to find existing phenotypes and to assess their quality and appropriateness for certain uses.
  • Discuss the importance of reporting phenotype definition features and data quality assessment for pragmatic research.

 

Podcast


Podcast Transcript: Download the transcript here.

 

CHATO design, pilot testing and update on current implementation and results

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September 2022 – In Grand Rounds 29, Dr. Kristi Williams, professor and nurse gerontologist at the University of Kansas, shares results and updates on the intervention, CHATO, for long-term care residents with Alzheimer's disease and other related dementias.

Speaker

Kristi Williams, PhD, RN

Kristi Williams, PhD, RN

Professor

University of Kansas School of Nursing

                      Download Webinar Slides

Learning Objectives

  • Describe the design of a pragmatic randomized clinical trial.
  • Become aware of common challenges to conducting research in Nursing Homes.
  • Describe a variety of proximal and distal outcome measures related to improved dementia care.

 

Podcast


Podcast transcript: Download the transcript here.

June 2022 Grand Rounds & Podcast

Update on IMPACT Funded Pilot Studies

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June 2022 – In Grand Rounds 28, Drs. Jennifer Gabbard and Ariel Green share research updates and experiences on IMPACT Cycle 2A Pilot Studies.

 

Jennifer Gabbard, MD on her pilot: Using Telemedicine to Improve Engagement in Advance Care Planning in Patients with Cognitive Impairment or Unrecognized Dementia

Ariel Green, MD, MPH, PhD on her pilot: ALIGN: Aligning Medications with What Matters Most

Webinar Recording

Download Webinar Slides

Speakers

Jennifer Gabbard, MDJennifer Gabbard, MD

Assistant Professor
Geriatrics and Palliative Medicine

Wake Forest School of Medicine

Ariel Green, MDAriel Green, MD, MPH, PhD

Associate Professor
Geriatrics Medicine and Gerontology

Johns Hopkins University School of Medicine

Learning Objectives

  • Understand the approach used to conduct an embedded pragmatic trial of advance care planning (ACP) intervention (TeleVoice) in outpatient primary care.
  • Understand the rationale and design of the ALIGN pilot study.
  • To appreciate the successes and challenges encountered in implementing an embedded pragmatic trial for people living with cognitive impairment (PLCI) and dementia (PLWD) in primary care.
  • To describe updates on our pilot progress to date and plans for a larger embedded pragmatic clinical trial.

 

Podcast


Podcast Transcript: Download the transcript here.
Bayliss and Boyd

Deprescribing Education vs Usual Care for Patients with Cognitive Impairment and Primary Care Clinicians: The OPTIMIZE Pragmatic Cluster Randomized Trial

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May 2022 – In Grand Rounds 27, the NIA IMPACT Collaboratory collaborated with the US Deprescribing Research Network (USDeN) to present on the OPTIMIZE Pragmatic Cluster Randomized Trial.

Download Webinar Slides

Speakers

Elizabeth BaylissElizabeth Bayliss, MD, MSPH

Senior Investigator
Institute for Health Research
Kaiser Permanente Colorado

Professor of Family Medicine
University of Colorado School of Medicine

 

Cynthia BoydCynthia Boyd, MD, MPH

Professor
Medicine, Epidemiology, and Health Policy & Management

Johns Hopkins University School of Medicine

Learning Objectives

  • Understand the approach used to conduct a pragmatic trial of deprescribing education in primary care
  • Describe cognitively impaired populations that may benefit from deprescribing education in primary care
  • Discuss potential adaptations of a deprescribing education intervention in a large health system

Podcast


Podcast Transcript: Download the transcript here.

Using a Pilot to Test and Refine Your Measurement Strategy

Posted on by Mia

January 2020 – In Grand Rounds 3, Dr. McCreedy presents a case example to describe how a pilot can be used to test the adequacy of existing data for evaluating an ePCT outcome. Dr. McCreedy also describes a potentially efficient ePCT design that accommodates under-detection in existing data while maintaining large-scale implementation and evaluation.

Speaker

Executive Committee, Technical Data Core

Assistant Professor, Brown University School of Public Health

Download Webinar Slides

Learning Objectives

  • Describe how a pilot study can be used to test the adequacy of existing data sources for the purposes of evaluating your ePCT.
  • Give three reasons why existing administrative data may suffer from under-detection of behaviors in persons with dementia.
  • Discuss an alternative ePCT design that addresses potential under-detection in existing administrative data sources.

 

Podcast


Podcast Transcript: Download the transcript here.

Related Articles and Resources

McCreedy EM, Yang X, Baier RR, Rudolph JL, Thomas KS, Mor V. Measuring effects of nondrug interventions on behaviors: music & memory pilot study. Journal of the American Geriatrics Society. 2019 Oct;67(10):2134-8.