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D-CARE: Results of a Pragmatic Intervention Trial and Implications for the GUIDE model

Posted on by Josee Meehan

April 16, 2026 – Grand Rounds 65,  David Reuben, MD, and Jeff Williamson, MD, MHS, presented D-CARE: Results of a Pragmatic Intervention Trial and Implications for the GUIDE model.

 

April 2026 Grand Rounds Webinar Slides

David Reuben, MD

Professor of Medicine
David Geffen School of Medicine
UCLA

Jeff Williamson, MD, MHS 

Professor, Chief of Geriatric Medicine, and Director for the Center for Healthcare Innovation at Wake Forest School of Medicine

Learning Objectives

  • To understand the differences between health system-based and community-based dementia care.
  • To recognize the differences between structured dementia care programs and usual care.
  • To interpret the implication of D-CARE's findings on dementia care and Medicare's GUIDE program.

Identifying and Engaging Care Partners through Electronic Health Records for Pragmatic Research

Posted on by Josee Meehan

March 2026 – Grand Rounds 64, IMPACT PCRO Core member Dr. Hillary Lum and guest speakers Drs. Julia Burgdorf and Jenny Portz, and Jody Long present on “Identifying and Engaging Care Partners through Electronic Health Records for Pragmatic Research.”

Webinar Slides

Hillary Lum, MD, PhD

IMPACT Patient/Caregiver Relevant Outcomes Core

Professor of Medicine, Division
of Geriatric Medicine,
Department of Medicine,
University of Colorado Anschutz

Jenny Portz, PhD, MSW

Associate Professor, General Internal Medicine, University of Colorado Anschutz

Julia Burgdorf, PhD

Research Scientist, Center for Home Care Policy & Research at VNS Health

Jody Long, MSN, MBA, RN, CEN

Director of Clinical Affairs, PointClickCare

Learning Objectives

  • Communicate the need and promise for improvement of dementia care with embedded pragmatic trials within dynamic health care settings.
  • Review what we have found to be key components of ePCT trial design and conduct for ensuring that study results are implementable.
  • Provide learnings of two ePCT trialists from The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care (D-CARE)

 

Home Time as a Patient-Centered Outcome in Pragmatic Trials: Promise, Pitfalls, and the Path Forward

Posted on by Josee Meehan

January 2026 – Grand Rounds 62, Drs. Hanson, Kim, Ankuda, and Van Houtven discuss home time as a patient-centered outcome in pragmatic trials.

Webinar Slides

Laura Hanson, MD, MPH

Professor, Division of Geriatric Medicine and Director, UNC Palliative Care Program, University of North Carolina School of Medicine

 

Claire Ankuda, MD, MPH

Associate Professor, Icahn School of Medicine at Mount Sinai

Dae Hyun Kim, MD, MPH, ScD

Associate Director of Marcus Institute for Aging Research, Associate Professor of Medicine, Harvard Medical School

Courtney Van Houtven, PhD

Professor, Population Health Sciences, Duke University School of Medicine and Duke-Margolis Institute for Health Policy

Learning Objectives

  • Understand the concept of home time as a patient‑centered, system‑relevant outcome measure and how it is operationalized across different clinical contexts.
  • Recognize the limitations, measurement challenges, and equity concerns associated with using home time as an outcome or performance metric in pragmatic clinical trials.
  • Reflect on emerging evidence and future directions for developing more person‑centered home time measures that better capture quality of life for older adults and caregivers.
Sullivan_June 2025 Grand Rounds card

Meta Lessons Learned from Pilot and Demonstration Projects Implementation 

Posted on by Erin Luers

June 2025 –  In Grand Rounds 57, Jennifer Sullivan, PhD, describes lessons learned from IMPACT Pilot and Demonstration Projects implementation data.

Speakers

Jennifer Sullivan, PhDJennifer Sullivan, PhD
Associate Professor, Brown University School of Public Health
Department of Health Service, Policy and Practice

Associate Director & Investigator
THRIVE COIN
VA Providence Healthcare System

Webinar Slides

Learning Objectives

  • Describe factors enabling and/or hindering pilot and demonstration project implementation
  • Understand which implementation strategies were being used by pilot and demonstration grants
  • Gain knowledge about how implementation progress was made by programs over the funding timelines

 

RWD Scholars headshots

Bridging Research and Practice: An Update from Real World Data Scholars

Posted on by Erin Luers

May 2025 – In Grand Rounds 56, the 2023 Real World Data Scholars presented on their research projects using the Long-Term Care (LTC) Data Cooperative dataset.

Webinar Slides

Headshot of Jinying Chen, PhD from the shoulders upJinying Chen, PhD

Boston University Chobanian & Avedisian School of Medicine

Validating Medication Orders by Leveraging Natural Language Processing

Headshot of Kenneth Lam, MD, MAS from the shoulders up, smiling and wearing a suit.

Kenneth Lam, MD, MAS  

University of Colorado
School of Medicine

Validation of Functional Measures in LTC EHR Data

Headshot of Lindsay White from the shoulders up.Lindsay White, PhD

University of Pennsylvania Perelman School of Medicine

Determination of Cognitive Status in NH Residents: The Utility of EHR Data

Headshot of Yongkang Zhang, Phd, MS from the shoulders up.

Yongkang Zhang, PhD, MS 

Weill Cornell Medical College

Evaluating LTC Data Cooperative EHRs to Study T2D among Nursing Home Residents

Improving Advance Care Planning for Seriously Ill Primary Care Patients: UC Health Care Planning Study

Posted on by Erin Luers

January 2025 - In Grand Rounds 52, Rebecca Sudore, MD, and Anne Walling, MD, PhD, present on "Improving Advance Care Planning (ACP) for Seriously Ill Primary Care Patients: UC Health Care Planning Study". They discuss the evolving ACP definition and research, along with lessons learned from their ACP PCORI pragmatic randomized control trial.

Speakers

Rebecca Sudore, MDRebecca Sudore, MD
Professor of Medicine,
University of California,
San Francisco

Anne Walling, MD, PhDAnne Walling, MD, PhD
Professor-in-Residence,
University of California,
Los Angeles

Webinar Slides

Learning Objectives

  • The Evolving ACP Definition & Research
  • Lessons for an ACP PCORI Pragmatic RCT
    • Identifying the cohort with validated algorithms
    • Constructing the ACP EMR Intervention Infrastructure
    • Healthcare navigator arm
    • Trial outcomes: NLP
    • Implementation Lessons

COVID Vaccination among Medicare Beneficiaries: Findings from an IMPACT Supplement

Posted on by Erin Luers

December 2024 - In Grand Rounds 51, Drs. Kaley Hayes, PharmD, PhD & Daniel Harris, PhD, MPH discuss the COVid VAXines Effects on the Aged (COVVAXAGE) database, which was the first project with NIA LINKAGE program (external data linkage to CMS data in NIA-funded projects); they walk through associated papers and lessons learned working with industry partners CVS Health and Walgreens.

Speakers

Daniel Harris, PhD, MPH
Assistant Professor
University of Delaware

Kaley Hayes, PharmD, PhD
Assistant Professor
Brown University

Webinar Slides

Learning Objectives

  • Be familiar with the NIA Linkage program and COVVAXAGE linked database of Medicare claims.
  • Understand the benefits of data linkages to Medicare data for studying COVID-19 vaccines and clinical outcomes.
  • Discuss findings from real-world COVID-19 vaccine studies examining use, safety, and effectiveness among older adults in the US.

 

October 2024 GR Decorative Card

Using Pilot Studies to Inform ePCTs in Hispanic/Latino People Living with Dementia and their Care Partners

Posted on by Erin Luers

October 2024 - In Grand Rounds 50, Drs. Ramirez and Samper-Ternent describe "Using Pilot Studies to Inform ePCTs in Hispanic/Latino People Living with Dementia and their Care Partners"

Speakers

Maggie Ramirez, PhD, MS, MS
Assistant Professor
University of Washington School of Public Health

Rafael Samper-Ternent, MD, PhD
Associate Professor
UTHealth Houston

Webinar Slides

Learning Objectives

  • Understand background of Hispanics/Latinos with Dementia
  • Describe Cultural Adaptation of Patient Priority Care using the Ecological Validity Model (EVM) and Heuristic Framework
  • Describe the key stages in culturally adapting an evidence-based intervention
  • Provide specific adaptations made to STAR-C for Latino caregivers
  • Apply these insights to enhance your own work with family caregivers

 

Grand Rounds September 2024, Susan Huang, MD, MPH

Evidence for Reducing Infections, Hospitalizations, and Antibiotic Resistant Pathogens in Nursing Homes through Universal Nasal Decolonization & Bathing with Chlorhexidine

Posted on by Erin Luers

September 2024 – In Grand Rounds 49, Dr. Huang presents on "Evidence for Reducing Infections, Hospitalizations, and Antibiotic Resistant Pathogens in Nursing Homes through Universal Nasal Decolonization & Bathing with Chlorhexidine."

Speakers

Susan Huang, MD, MPH 
Professor, Infectious Diseases,
Medical Director, Epidemiology and Infection Prevention,
University of California Irvine School of Medicine

Webinar Slides

Learning Objectives

  • Review the rise and risks of MultiDrug-Resistant Organisms (MDROs) in nursing homes (NH)
  • Describe decolonization, why it’s needed, and how it works; focusing on Chlorhexidine
  • Review clinical trial evidence for decolonization in hospitals and NHs
  • Summarize the NH Decolonization Toolkit and implementation