D-CARE: Results of a Pragmatic Intervention Trial and Implications for the GUIDE model

April 16, 2026 – Grand Rounds 65,  David Reuben, MD, and Jeff Williamson, MD, MHS, presented D-CARE: Results of a Pragmatic Intervention Trial and Implications for the GUIDE model.

 

David Reuben, MD

Professor of Medicine
David Geffen School of Medicine
UCLA

Jeff Williamson, MD, MHS 

Professor, Chief of Geriatric Medicine, and Director for the Center for Healthcare Innovation at Wake Forest School of Medicine

Learning Objectives

  • To understand the differences between health system-based and community-based dementia care.
  • To recognize the differences between structured dementia care programs and usual care.
  • To interpret the implication of D-CARE's findings on dementia care and Medicare's GUIDE program.

Identifying and Engaging Care Partners through Electronic Health Records for Pragmatic Research

March 2026 – Grand Rounds 64, IMPACT PCRO Core member Dr. Hillary Lum and guest speakers Drs. Julia Burgdorf and Jenny Portz, and Jody Long present on “Identifying and Engaging Care Partners through Electronic Health Records for Pragmatic Research.”

Hillary Lum, MD, PhD

IMPACT Patient/Caregiver Relevant Outcomes Core

Professor of Medicine, Division
of Geriatric Medicine,
Department of Medicine,
University of Colorado Anschutz

Jenny Portz, PhD, MSW

Associate Professor, General Internal Medicine, University of Colorado Anschutz

Julia Burgdorf, PhD

Research Scientist, Center for Home Care Policy & Research at VNS Health

Jody Long, MSN, MBA, RN, CEN

Director of Clinical Affairs, PointClickCare

Learning Objectives

  • Communicate the need and promise for improvement of dementia care with embedded pragmatic trials within dynamic health care settings.
  • Review what we have found to be key components of ePCT trial design and conduct for ensuring that study results are implementable.
  • Provide learnings of two ePCT trialists from The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care (D-CARE)

 

LEAP! Rx: A randomized trial of a pragmatic approach to lifestyle medicine

December 2025 - In Grand Rounds 61, Amber Watts, PhD and Amanda N. Szabo-Reed, PhD discuss “LEAP! Rx: A randomized trial of a pragmatic approach to lifestyle medicine.”

Speakers

Amber Watts, PhD
Associated Professor
University of Kansas
Director, BRANCH LAb

Amanda N. Szabo-Reed, PhD
Research Associate Professor
University of Kansas Medical Center

Learning Objectives

  • Understand why exercise is important for Alzheimer’s disease prevention.
  • Recognize barriers to translating exercise research into clinical practice.
  • Learn how the LEAP! Rx trial was designed and implemented.
  • Compare outcomes and adherence between physician-referred and self-referred participants.
  • Explore strategies for supporting long-term exercise habits in older adults.
Kern picture, Grand Rounds Feb 2025

Improving How PLWD are Selected for Care Coordination: ePCT in an ACO

February 2025 - Lisa Kern, MD, MPH, discusses "IMPACT Demonstration Project | Improving How People Living with Dementia are Selected for Care Coordination: Pragmatic Clinical Trial Embedded in an Accountable Care Organization"

Speakers

Lisa Kern, MD, MPH
Associate Professor
Weill Cornell Medicine

Learning Objectives

  • Understand the concept of healthcare fragmentation in general
  • Understand the relevance of healthcare fragmentation specifically for people
    living with dementia
  • Reflect on the results of a pragmatic clinical trial that included people living
    with dementia who had highly fragmented care

 

Dr. Possin Grand Rounds card

Augmenting Nurse Support and EHR Integration for the Pragmatic Trial of the TabCAT Brain Health Assessment

April 2025 – In Grand Rounds 55, Katherine Possin, PhD, discusses "Augmenting Nurse Support and Electronic Health Record (EHR) Integration for the Pragmatic Trial of the TabCAT Brain Health Assessment (TabCAT-BHA)." TabCAT-BHA is a software platform owned by UCSF to provide diagnosis in MCI and dementia.

Speakers

Katherine Possin, PhD

Katherine Possin, PhD
John Douglas French Alzheimer’s Foundation Endowed Professorship
Professor in Residence
Department of Neurology
UCSF Memory and Aging Center

Learning Objectives

  • Learn about the DetectCID Consotrium and TabCAT-Brain Health Assessment
  • Understand implementation of TabCAT-BHA as part of a diagnostic care pathway at UCSF primary care (DetectCID-1) and Kaiser Permanente Southern California primary care (DetectCID-2)
  • Understand scaling TabCAT-BHA & Brain Health Consultation

 

GR card - Malaz Boustani

5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care: Pragmatic Clinical Trial

March 2025 - In Grand Rounds 54, Malaz Boustani, MD, MPH, discusses transforming brain health with early detection of cognitive problems in the primary care setting using the 5-cog paradigm.

Speakers

Malaz Boustani, MD, MPH

Richard M. Fairbanks Professor of Aging Research,
Indiana University School of Medicine

Research Scientist,
Indiana University Center for Aging Research

Learning Objectives

  • Why early detection of cognitive problems in primary care
    • Need versus demand
    • 0 minutes $1 dollar strategies
  • Review 5 COG 1.0 results
  • Overview of 5 COG 2.0 study design and flow
  • Current status of the 5 Cog 2.0 study
  • Agile science and its derivatives
IMPACT Launches New HE Certificate Training Program

IMPACT Certificate Program – Best Practices for Integrating Health Equity into ePCTs for Dementia Care

IMPACT Collaboratory introduced its latest online training program designed to empower researchers at all levels in integrating health equity considerations into embedded Pragmatic Clinical Trials (ePCTs) for people living with dementia (PLWD) and their care partners.

Program Overview:

This comprehensive training program, aligned with the “Best Practices for Integrating Health Equity into ePCTs for Dementia Care” document, equips researchers with the knowledge and skills to incorporate health equity considerations into design and research activities at every level of ePCTs for people living with dementia. The program covers six essential topic areas:

· Getting Started

· Community Partner Engagement

· Design and Analysis

· Intervention Design and Implementation

· Healthcare System and Participant Selection

· Selecting Outcomes

Key Features:

· Free, accessible online training

· Six courses, each including 2-5 brief and engaging videos

· Self-paced learning, typically completed in 3 hours or less

· Certificate upon successful completion of the program

Access the Training:

Visit the IMPACT Collaboratory HE certificate web page for details and links to set up your free learning account. This account not only provides access to the health equity training program but also to other certificate programs and training materials.

Long-Term Care Data Cooperative Releases Funding Opportunity for the New Real World Data Scholars Program

The Long-Term Care (LTC) Data Cooperative announces a request for applications for the newly established 2023 Real World Data Scholars Program. This program supports the development of advanced graduate students, postdoctoral fellows, and early-career faculty who are interested in developing their expertise and experience in working with electronic health record (EHR) data.

This program offers a unique opportunity to be among the first users of the LTC Data Cooperative’s EHR data and to characterize the data for future users through validation and analyses. It is available for investigators at all levels who are interested in developing their expertise and experience working with EHR data.

The Real World Data Scholars Program will fund up to three investigators for a 12-month training grant. Selected scholars will work with the designers of the LTC Data Cooperative to test and establish the validity or reliability of key measures within this new data resource. Accepted scholars will be partnered with a mentor who is well-versed in analyzing EHR data and can provide support and direction for scholars.

Awards are for 12 months and up to $50,000 in direct costs; awardees are expected to devote 25-50% effort toward the goals of the program. Indirect costs are calculated at 8%. Applicants should be experienced using large-scale administrative and/or clinical data (e.g., EHR data, Medicare claims, Minimum Data Set, registry data, etc.). Individuals with a background in pharmacoepidemiology, natural language processing, or clinical investigations are also encouraged to apply. Applicants from under-represented racial and ethnic groups as well as individuals with disabilities are strongly encouraged to apply.

Applicants must be associated with an academic institution or academic medical center and be citizens or permanent residents of the United States. All research must be performed within the United States.

The RFA, including instructions to apply, can be found here. The application period opens Friday, June 16 at 9 AM ET and applications are due Friday, August 4, 2023 by 5 PM ET. An informational webinar will be hosted on Tuesday, June 13, 2023 at 3:00 PM ET to provide an overview of the program and application. Investigators will have the opportunity to ask questions. Pre-registration is required.
Watch the webinar recording.

Email RWDScholars@brown.edu with questions.

 

About the LTC Data Cooperative

The LTC Data Cooperative is funded as a supplement to the IMPACT Collaboratory by the National Institute on Aging (U54AG063546-S6) and aims to improve the quality of care within nursing homes by compiling the most comprehensive electronic health record (EHR) data for nursing home residents nationwide.

IMPACT hosts special webinar introducing the Long-Term Care Data Cooperative

December 2022 - The IMPACT Collaboratory hosted a special webinar event December 7, featuring leaders from the Long-Term Care (LTC) Data Cooperative who provided an introduction and overview to this powerful new resource. IMPACT’s Vince Mor, PhDDavid Dore, PharmD, PhD, from Exponent, and David Gifford, MD, MPH from the American Health Care Association (AHCA) shared insightful information with participants about the Data Cooperative, its membership, how to join, and options for data access.

Download webinar slides.                                  Download the transcript.

The LTC Data Cooperative will:

  • Assist providers with health care operations, including care coordination, risk stratification and quality performance reporting.
  • Support public health monitoring for medical conditions and infections, including COVID-19.
  • Enable observational studies of the LTC population, ranging from comparative treatment effectiveness studies, to epidemiological studies of risk to pharmaco-epidemiological studies.
  • Facilitate provider and patient recruitment into clinical research studies, including stage 3 and 4 embedded pragmatic clinical trials.

Vince Mor, PhD
Brown University

 

David Gifford, MD, MPH
American Health Care Association

 

David Dore, PharmD, PhD
Exponent, Inc.

New video shares Health Care Systems Scholar Dr. Hillary Lum’s experience creating a research program to improve dementia care

Hillary Lum, MD, PhD, IMPACT Health Care System Scholar, has created a brief video sharing the story of her 1-year journey with The University of Colorado UC Health preparing to conduct real world research to improve dementia care.

The brief video describes the goals and progress over the last year as Dr. Lum and her colleagues developed a program to improve dementia care by improving communication and care communication in dementia care by using health information tools such as patient portals.

Dr. Hillary Lum Shares Her Experience Developing a Program to Conduct Real-World Research in People Living with Dementia from NIA IMPACT Collaboratory on Vimeo.