Lessons From the First Decade of the NIH Pragmatic Trials Collaboratory

February 2022 – In Grand Rounds 24, Drs. Hernandez, Curtis and Weinfurt, the Principal Investigators of the NIH Pragmatic Trials Collaboratory, describe how the Collaboratory began ten years ago, the current state of their research, and where they see the research going in the future.

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Adrian Hernandez, MD, MHS

Adrian Hernandez, MD, MHS
Executive Director,
Duke Clinical Research Institute
Vice Dean, Duke University School of Medicine

Leslie Curtis, PhD

Leslie Curtis, PhD
Professor and Chair
Department of Population Health Sciences
Duke School of Medicine
Faculty member, Duke Clinical Research Institute

Kevin Weinfurt, PhD

Kevin Weinfurt, PhD
Professor and Vice Chair of Research
Department of Population Health Sciences
Duke University Medical Center
Faculty member, Duke Clinical Research Institute

Learning Objectives

  • Understand the goals of the NIH Pragmatic Trials Collaboratory
  • Describe the state of the science of pragmatic trials based on experiences from the Collaboratory’s first decade
  • Identify opportunities for advances in pragmatic trials methodology

Healthcare-Generated Data to Identify People Living with Dementia for Embedded Pragmatic Trials

January 2022 – In Grand Rounds 23, Dr. Bynum describes the use of data to identify people living with dementia as well as strengths, challenges and potential equity gaps when using a healthcare-generated data approach in pragmatic clinical trials.

Speaker

Julie Bynum, MD, MPH

Julie Bynum, MD, MPH

Margaret Terpenning Professor of Medicine

University of Michigan

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Learning Objectives

  • Understand the use of data to achieve pragmatic study aims
  • Identify strengths & challenges when use Healthcare-generated data (billing or electronic health record data) for participant identification
  • Identify threats to Health Equity and Generalizability related to choices about data use.

 

Partnering with People Living with Dementia and Care Partners in Embedded Pragmatic Clinical Trials

December 2021 – Grand Rounds 22 features a panel of participants sharing their experiences in stakeholder engagement in ePCTs for people living with AD/ADRD and their care partners. Perspectives shared include that of a researcher, a stakeholder engagement expert and people living with dementia.

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Speakers

Gary Epstein-Lubow, MD

Gary Epstein-Lubow, MD
Team Leader, IMPACT Engaging Partners Team
Associate Professor of Psychiatry and Human Behavior
Associate Professor of Medical Science, Alpert Medical School of Brown University
Associate Professor of Health Services, Policy and Practice, Brown University School of Public Health

 


Heidi GilHeidi Gil
Executive Committee Member,
IMPACT Engaging Partners Team

Chief Strategy Officer, LiveWell

Learning Objectives

    • Understand the need/benefits of engaging people living with dementia and care partners in every aspect of dementia care research
    • Identify how all stakeholders can be empowered and engaged as co-partners in research
    • Explore lessons learned and resources available to conduct research differently