Adaptation of behavioral interventions and use of FRAME

January 2023 – In Grand Rounds 33, Dr. Wiltsey Stirman dives into the adaptations of behavioral interventions and describes how the FRAME process can be used to document those adaptations and modifications.

Speaker

Shannon Wiltsey Stirman, PhDShannon Wiltsey Stirman, PhD

Associate Professor
Psychiatry and Behavioral Sciences

Stanford University

Learning Objectives

  • Discuss factors that should be considered when adapting behavioral interventions.
  • Describe how the FRAME can be used to document adaptations.
  • Provide examples of study designs to investigate the impact of adaptations.

 

IMPACT hosts special webinar introducing the Long-Term Care Data Cooperative

December 2022 - The IMPACT Collaboratory hosted a special webinar event December 7, featuring leaders from the Long-Term Care (LTC) Data Cooperative who provided an introduction and overview to this powerful new resource. IMPACT’s Vince Mor, PhDDavid Dore, PharmD, PhD, from Exponent, and David Gifford, MD, MPH from the American Health Care Association (AHCA) shared insightful information with participants about the Data Cooperative, its membership, how to join, and options for data access.

Download webinar slides.                                  Download the transcript.

The LTC Data Cooperative will:

  • Assist providers with health care operations, including care coordination, risk stratification and quality performance reporting.
  • Support public health monitoring for medical conditions and infections, including COVID-19.
  • Enable observational studies of the LTC population, ranging from comparative treatment effectiveness studies, to epidemiological studies of risk to pharmaco-epidemiological studies.
  • Facilitate provider and patient recruitment into clinical research studies, including stage 3 and 4 embedded pragmatic clinical trials.

Vince Mor, PhD
Brown University

 

David Gifford, MD, MPH
American Health Care Association

 

David Dore, PharmD, PhD
Exponent, Inc.

Addressing vulnerability in cluster randomized trials involving people living with dementia in nursing homes

November 2022 – In Grand Rounds 31, Dr. Weijer shares six different vulnerabilities, and key methods of protection to address them, in cluster randomized trials for people living with dementia in long-term care home settings.

Speaker

Charles Weijer, MD, PhDCharles Weijer, MD, PhD

Professor

Western University

Developing standards and quality metrics for clinical phenotyping using EHR data in pragmatic clinical trials

October 2022 – In Grand Rounds 30, Dr. Richesson describes the use of electronic health records (EHR) to develop standards and quality metrics for computable phenotyping in pragmatic clinical trials.

Speaker

Rachel Richesson, PhD, MPH, FACMI

Rachel Richesson, PhD, MPH, FACMI

Professor
Informatics & Learning Health Sciences

University of Michigan School of Medicine

                       Download Webinar Slides

Learning Objectives

  • Define computable phenotyping and discuss its relevance to pragmatic clinical trials.
  • Discuss approaches to find existing phenotypes and to assess their quality and appropriateness for certain uses.
  • Discuss the importance of reporting phenotype definition features and data quality assessment for pragmatic research.

 

CHATO design, pilot testing and update on current implementation and results

September 2022 – In Grand Rounds 29, Dr. Kristi Williams, professor and nurse gerontologist at the University of Kansas, shares results and updates on the intervention, CHATO, for long-term care residents with Alzheimer's disease and other related dementias.

Speaker

Kristi Williams, PhD, RN

Kristi Williams, PhD, RN

Professor

University of Kansas School of Nursing

                      Download Webinar Slides

Learning Objectives

  • Describe the design of a pragmatic randomized clinical trial.
  • Become aware of common challenges to conducting research in Nursing Homes.
  • Describe a variety of proximal and distal outcome measures related to improved dementia care.

 

June 2022 Grand Rounds & Podcast

Update on IMPACT Funded Pilot Studies

June 2022 – In Grand Rounds 28, Drs. Jennifer Gabbard and Ariel Green share research updates and experiences on IMPACT Cycle 2A Pilot Studies.

 

Jennifer Gabbard, MD on her pilot: Using Telemedicine to Improve Engagement in Advance Care Planning in Patients with Cognitive Impairment or Unrecognized Dementia

Ariel Green, MD, MPH, PhD on her pilot: ALIGN: Aligning Medications with What Matters Most

Webinar Recording

Download Webinar Slides

Speakers

Jennifer Gabbard, MDJennifer Gabbard, MD

Assistant Professor
Geriatrics and Palliative Medicine

Wake Forest School of Medicine

Ariel Green, MDAriel Green, MD, MPH, PhD

Associate Professor
Geriatrics Medicine and Gerontology

Johns Hopkins University School of Medicine

Learning Objectives

  • Understand the approach used to conduct an embedded pragmatic trial of advance care planning (ACP) intervention (TeleVoice) in outpatient primary care.
  • Understand the rationale and design of the ALIGN pilot study.
  • To appreciate the successes and challenges encountered in implementing an embedded pragmatic trial for people living with cognitive impairment (PLCI) and dementia (PLWD) in primary care.
  • To describe updates on our pilot progress to date and plans for a larger embedded pragmatic clinical trial.

 

Bayliss and Boyd

Deprescribing Education vs Usual Care for Patients with Cognitive Impairment and Primary Care Clinicians: The OPTIMIZE Pragmatic Cluster Randomized Trial

May 2022 – In Grand Rounds 27, the NIA IMPACT Collaboratory collaborated with the US Deprescribing Research Network (USDeN) to present on the OPTIMIZE Pragmatic Cluster Randomized Trial.

Download Webinar Slides

Speakers

Elizabeth BaylissElizabeth Bayliss, MD, MSPH

Senior Investigator
Institute for Health Research
Kaiser Permanente Colorado

Professor of Family Medicine
University of Colorado School of Medicine

 

Cynthia Boyd, MD, MPHCynthia Boyd, MD, MPH

Professor
Medicine, Epidemiology, and Health Policy & Management

Johns Hopkins University School of Medicine

Learning Objectives

  • Understand the approach used to conduct a pragmatic trial of deprescribing education in primary care
  • Describe cognitively impaired populations that may benefit from deprescribing education in primary care
  • Discuss potential adaptations of a deprescribing education intervention in a large health system

Mission Moment: Barbara Healy, RN, MSN, Care Coordinator, MassGeneral Brigham Integrated Care Management Program

Barbara Healy, RN, BSN, MSN, CCM, NC-BC, Care Coordinator, MassGeneral Brigham Integrated Care Management Program provided this year’s mission moment for the IMPACT Collaboratory 3rd Annual Steering Committee & Business Planning Meeting, held on April 5, 2022.

Ms. Healy shared her unique experience in her role as nursing care manager working on the front line as a care coordinator in a pilot pragmatic clinical trial embedded within a healthcare system.

Ms. Healy provided valuable insights from the perspective of a frontline member of the healthcare team working with researchers to conducting pragmatic clinical trial among people living with dementia in real world care settings. She also shared lessons learned and themes for consideration as researchers design and implement pragmatic trials embedding in real world settings in the future.

Remarks from the National Institute on Aging

IMPACT Richard J. Hodes, MD, Director of the National Institute of Aging reflected on what he described as the enormous success of the first three years of the IMPACT Collaboratory during the IMPACT Collaboratory 3rd Annual Steering Committee & Business Planning Meeting, held on April 5, 2022.

Dr. Hodes discussed the development of a strong network of investigators and infrastructure for conducting embedded pragmatic clinical trials (ePCTs) in people living with dementia and their care partners, the development of an array of training resources, and IMPACT’s response to the COVID pandemic.  He closed with anticipation of future successes including continued investments in training, infrastructure development, knowledge dissemination, and stakeholder engagement.

Embedding Health Equity in a Cluster Randomized Trial of an Advance Care Planning Intervention

April 2022 – In Grand Rounds 26, Kimberly S. Johnson, MD, professor of medicine and director of the Duke Center for Research to Advance Healthcare Equity at Duke Health, shares her experience in leading an embedded pragmatic clinical trial focused on health equity in advance care planning.

Speaker

Kimberly S. Johnson, MD

 

Kimberly S. Johnson, MD

Professor of Medicine

Director of the Duke Center for Research to Advance Healthcare Equity, Duke Health

                        Download webinar slides

Learning Objectives

  • Describe current gaps and challenges in equitable conduct and reporting of research findings.
  • Describe strategies to promote diversity, equity, and inclusion throughout the research process.
  • Identify at least one opportunity to embed processes to increase enrollment of underrepresented populations in your work and promote equitable access to your research studies.