Technical Data

IMPACT Collaboratory announces two new resources to aid in the design of ePCTs

Posted on by Sonya Sutton

Two IMPACT Collaboratory cores have developed new tools to assist in the design of embedded pragmatic trials (ePCTs) for people living with dementia.

The Design and Statistics Core has developed statistical tools and novel methodology to aid in the design and analyses of ePCTs for people living with dementia. These methods, manuscripts, statistical programs, and interactive web applications are now available to help researchers calculate sample sizes, intra-cluster correlations, and power for stepped wedge and cluster randomized trials.

The content can be accessed in IMPACT’s new Statistical Tools web page. The tools will be updated as new statistical resources become available.

The Technical Data Core has generated prevalence estimates of Alzheimer’s disease and related dementias (ADRD) for the Medicare population by geographic regions (e.g., state, hospital referral regions) and settings of care (hospitals, emergency departments, skilled nursing facilities). These data include the total number of Medicare beneficiaries, total number of beneficiaries with ADRD, and key demographic characteristics (age, sex, race, dual eligibility). Data from 2020 and 2021 are available for Medicare Advantage and Traditional Medicare populations. The prevalence data are available with consultation to help investigators planning ePCTs for people living with dementia in these settings of care.

Learn more about United States Dementia Prevalence Estimates among Medicare Beneficiaries. Interested investigators may request a consultation with an expert.

 

 

CAPRA Data Brief | health care use patterns among older adults with dementia

Posted on by Sonya Sutton

IMPACT’s Cameron Gettel, MD and Julie Bynum, MD, MPH are among the authors of the CAPRA Data Brief on health care use patterns among older adults with dementia. The brief was developed by the Center to Accelerate Population Research on Alzheimer’s (CAPRA) at the University of Michigan.

Authors demonstrated the use of Medicare claims to examine healthcare use patterns among older adults with ADRD using datasets provided by the Impact Collaboratory. The brief cites the increase in emergency care, hospitalization, and skilled nursing facility admissions for Medicare recipients and an increased need for planning and care for people with Alzheimer’s Disease and Related Dementias (ADRD) in the U.S.

Read the brief here.

Is Learning Worth the Trouble? — Improving Health Care System Participation in Embedded Research

Posted on by Sonya Sutton

Is Learning Worth the Trouble? — Improving Health Care System Participation in Embedded Research

July 1, 2021

A paper about the importance of embedded pragmatic clinical trials (ePCTs) in generating real-world evidence without the limitations associated with observational studies or the time, expense, and lack of generalizability that are barriers to conducting conventional randomized clinical trials. The authors’ experience working in the coordinating center of the National Institutes of Health (NIH) Health Care Systems Research Collaboratory has demonstrated the feasibility of conducting innovative multicenter ePCTs for various conditions. Read the full article here.